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HLA Single Antigen Bead Assay for Class I IgG Antibodies DSA-SAB Class I Test

5,150 د.إ

-10%

The HLA Single Antigen Bead Assay for Class I IgG Antibodies, commonly referred to as the DSA-SAB Class I Test, is a highly specialized laboratory procedure designed to detect and identify specific donor-specific antibodies (DSAs) against Class I HLA antigens. These antibodies can play a significant role in the rejection of transplanted organs and are crucial markers for assessing the compatibility between organ donors and recipients. The test employs a sophisticated technique that uses microbeads coated with purified HLA antigens to accurately identify the presence and specificity of IgG antibodies targeting HLA Class I molecules.

Conducted at DNA Labs UAE, this test is pivotal for patients undergoing or considering organ transplantation, as the presence of DSAs can significantly affect the outcome and longevity of the transplant. By identifying these antibodies, healthcare providers can make informed decisions about donor selection, immunosuppressive therapy, and post-transplant management to improve transplant success rates and patient outcomes.

The cost of the DSA-SAB Class I Test at DNA Labs UAE is 5150 AED. This investment in testing is crucial for ensuring the best possible match between donor and recipient, thereby enhancing the chances of transplant success and long-term health benefits for patients requiring organ transplants.

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HLA SINGLE ANTIGEN BEAD ASSAY FOR CLASS I IgG ANTIBODIES DSA-SAB CLASS I Test

Test Name: HLA SINGLE ANTIGEN BEAD ASSAY FOR CLASS I IgG ANTIBODIES DSA-SAB CLASS I Test

Components: Price: 5150.0 AED

Sample Condition: 2 mL (1 mL min) serum from 1 SST. Ship refrigerated or frozen. Please provide a brief clinical history.

Report Delivery: 10-12 days

Method: Luminex X-Map technology

Test Type: Transplantation

Doctor: Nephrologist

Test Department:

Pre Test Information: Please provide a brief clinical history.

Test Details:

The HLA single antigen bead assay for class I IgG antibodies is a diagnostic test used to identify the presence of donor-specific antibodies (DSA) in patients who have received organ transplants. This test is based on the detection of antibodies against human leukocyte antigens (HLA), which are proteins found on the surface of cells that play a critical role in the immune response.

The HLA single antigen bead assay involves the use of microbeads that are coated with specific HLA antigens. These beads are incubated with the patient’s serum, and any antibodies present in the serum will bind to the corresponding HLA antigen on the bead. The beads are then washed to remove any unbound antibodies, and a fluorescently labeled secondary antibody is added to detect the bound antibodies. The level of fluorescence on each bead is measured using a flow cytometer, and the results are analyzed to determine the presence and strength of DSA.

The assay can detect antibodies against multiple HLA antigens simultaneously, allowing for a comprehensive assessment of the patient’s immune response. The HLA single antigen bead assay for class I IgG antibodies is considered a highly sensitive and specific test for the detection of DSA and is commonly used in clinical practice to monitor transplant patients for signs of rejection.

The test can also be used to identify potential donors who are compatible with the patient’s immune system and to guide the selection of immunosuppressive therapies to prevent rejection.

Test Name HLA SINGLE ANTIGEN BEAD ASSAY FOR CLASS I IgG ANTIBODIES DSA-SAB CLASS I Test
Components
Price 5150.0 AED
Sample Condition 2 mL (1 mL min) serum from 1 SST . Ship refrigerated or frozen. Give brief clinical history.
Report Delivery 10-12 days
Method Luminex X-Map technology
Test type Transplantation
Doctor Nephrologist
Test Department:
Pre Test Information Give brief clinical history.
Test Details

The HLA single antigen bead assay for class I IgG antibodies is a diagnostic test used to identify the presence of donor-specific antibodies (DSA) in patients who have received organ transplants. This test is based on the detection of antibodies against human leukocyte antigens (HLA), which are proteins found on the surface of cells that play a critical role in the immune response.

The HLA single antigen bead assay involves the use of microbeads that are coated with specific HLA antigens. These beads are incubated with the patient’s serum, and any antibodies present in the serum will bind to the corresponding HLA antigen on the bead. The beads are then washed to remove any unbound antibodies, and a fluorescently labeled secondary antibody is added to detect the bound antibodies.

The level of fluorescence on each bead is measured using a flow cytometer, and the results are analyzed to determine the presence and strength of DSA. The assay can detect antibodies against multiple HLA antigens simultaneously, allowing for a comprehensive assessment of the patient’s immune response.

The HLA single antigen bead assay for class I IgG antibodies is considered a highly sensitive and specific test for the detection of DSA, and is commonly used in clinical practice to monitor transplant patients for signs of rejection. The test can also be used to identify potential donors who are compatible with the patient’s immune system, and to guide the selection of immunosuppressive therapies to prevent rejection.