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HLA Pre-Transplant Workup Sensitized Recipient Panel 4 Test

Original price was: 15,600 د.إ.Current price is: 14,040 د.إ.

-10%

The “HLA Pre-Transplant Workup Sensitized Recipient Panel 4 Test” is a specialized diagnostic procedure conducted at DNA Labs UAE, designed to evaluate potential transplant recipients for sensitization to human leukocyte antigens (HLA). This test is crucial for identifying individuals who have developed antibodies against HLA, which can significantly impact the success rate of organ transplants. Sensitization can occur due to previous transplants, blood transfusions, or pregnancies, making it essential to assess the compatibility between donor and recipient to minimize the risk of organ rejection.

The test involves a comprehensive analysis of the recipient’s immune response to various HLA antigens, providing invaluable information for the medical team to make informed decisions regarding transplantation strategies. The cost of this detailed and critical assessment is 14,040 AED, reflecting the sophisticated technology and expertise required to conduct the test and interpret its results. Conducted at DNA Labs UAE, a facility known for its state-of-the-art technology and highly qualified professionals, this test is a vital step in the pre-transplant evaluation process, ensuring the highest possible success rates for organ transplants by identifying and addressing potential challenges related to HLA sensitization.

Description

HLA PRE-TRANSPLANT WORKUP SENSITIZED RECIPIENT PANEL 4 Test

Test Name: HLA PRE-TRANSPLANT WORKUP SENSITIZED RECIPIENT PANEL 4 Test

Components:

HLA DNA Typing for Kidney / Liver transplant, High resolution NGS
HLA T & B cell lymphocyte cross match vs potential donor
HLA T & B cell lymphocyte flow cytometry cross match vs potential donor
HLA Panel Reactive IgG antibodies (PRA) Screen Luminex
Single antigen bead (SAB) IgG Class I & II Luminex

Price: 14040.0 AED

Sample Condition:

RECIPIENT: 6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube AND 9 mL (6 mL min.) serum from 3 SST’s AND 4 mL (2 mL min.) whole blood in 1 Lavender top (EDTA) tube AND 4 mL (2 mL min.) whole blood in 1 Green Top (Sodium Heparin) tube.
Collect specimen preferably 48 hours after dialysis.
Ship at 18-22°C. DO NOT REFRIGERATE OR FREEZE.
Doctor’s prescription on the letterhead with 1 photograph each of recipient and donor duly stamped AND Consent form for HLA Typing for Solid organ transplant (Form 33) is mandatory.

Report Delivery: 10-12 days

Method: Complement Dependent Cytotoxicity with DTT treatment, Reverse SSOP – Luminex, Luminex X-Map technology, Flow cytometry, Sequence based Typing (SBT)

Test Type: Transplantation

Doctor: Nephrologist

Test Department:

Pre Test Information: Doctor’s prescription on the letterhead with 1 photograph each of recipient and donor duly stamped AND Consent form for HLA Typing for Solid organ transplant (Form 33) is mandatory.

Test Details:

The sensitized recipient panel 4 (SRP4) test is a blood test that is used to determine the level of antibodies in a potential organ transplant recipient’s blood. This test is typically performed as part of the pre-transplant workup for individuals who have been sensitized to human leukocyte antigens (HLA). HLA are proteins that are found on the surface of cells in the body. These proteins help the immune system distinguish between “self” cells and “foreign” cells. When a person receives a blood transfusion or an organ transplant, their immune system may recognize the HLA on the donor cells as foreign and mount an immune response against them. This immune response can lead to rejection of the transplanted organ.

The SRP4 test is used to determine the level of antibodies in the recipient’s blood that may react with the donor’s HLA. This information can help the transplant team select a donor organ that is less likely to be rejected by the recipient’s immune system. The SRP4 test is performed using a panel of HLA antigens that are commonly found in the population. The recipient’s blood is mixed with the HLA antigens, and any antibodies in the recipient’s blood that react with the antigens are detected using a special technique called flow cytometry.

The results of the SRP4 test are reported as a percentage of the panel that the recipient is sensitized to. For example, if the recipient is sensitized to 50% of the panel, it means that they have antibodies that react with half of the HLA antigens tested. The transplant team will use the results of the SRP4 test, along with other factors such as the recipient’s medical history and the availability of donor organs, to determine the best course of treatment for the individual. In some cases, the transplant may be postponed or the recipient may be treated with medications to reduce their antibody levels before the transplant can take place.

Test Name	HLA PRE-TRANSPLANT WORKUP SENSITIZED RECIPIENT PANEL 4 Test
Components	Recipient : HLA DNA Typing for Kidney / Liver transplant,High resolution NGS HLA T & B cell lymphocyte cross match vs potential donor* HLA T & B cell lymphocyte flow cytometry cross match vs potential donor HLA Panel Reactive IgG antibodies (PRA) Screen Luminex Single antigen bead (SAB) IgG Class I & II Luminex
Price	14040.0 AED
Sample Condition	RECIPIENT: 6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube AND 9 mL (6 mL min.) serum from 3 SST’s AND 4 mL (2 mL min.) whole blood in 1 Lavender top (EDTA) tube AND 4 mL (2 mL min.) whole blood in 1 Green Top (Sodium Heparin) tube. Collect specimen preferably 48 hours after dialysis. Ship at 18\u0192??22?\u00f8C. DO NOT REFRIGERATE OR FREEZE.Doctor’s prescription on the letter head with 1 photograph each of recipient and donor duly stamped AND Consent form for HLA Typing for Solid organ transplant (Form 33) is mandatory.
Report Delivery	10-12 days
Method	Complement Dependent Cytotoxicity with DTT treatment, Reverse SSOP – Luminex, Luminex X-Map technology, Flow cytometry, Sequence based Typing (SBT)
Test type	Transplantation
Doctor	Nephrologist
Test Department:
Pre Test Information	Doctor’s prescription on the letter head with 1 photograph each of recipient and donor duly stamped AND Consent form for HLA Typing for Solid organ transplant (Form 33) is mandatory.
Test Details	The sensitized recipient panel 4 (SRP4) test is a blood test that is used to determine the level of antibodies in a potential organ transplant recipient’s blood. This test is typically performed as part of the pre-transplant workup for individuals who have been sensitized to human leukocyte antigens (HLA). HLA are proteins that are found on the surface of cells in the body. These proteins help the immune system distinguish between “self” cells and “foreign” cells. When a person receives a blood transfusion or an organ transplant, their immune system may recognize the HLA on the donor cells as foreign and mount an immune response against them. This immune response can lead to rejection of the transplanted organ. The SRP4 test is used to determine the level of antibodies in the recipient’s blood that may react with the donor’s HLA. This information can help the transplant team select a donor organ that is less likely to be rejected by the recipient’s immune system. The SRP4 test is performed using a panel of HLA antigens that are commonly found in the population. The recipient’s blood is mixed with the HLA antigens, and any antibodies in the recipient’s blood that react with the antigens are detected using a special technique called flow cytometry. The results of the SRP4 test are reported as a percentage of the panel that the recipient is sensitized to. For example, if the recipient is sensitized to 50% of the panel, it means that they have antibodies that react with half of the HLA antigens tested. The transplant team will use the results of the SRP4 test, along with other factors such as the recipient’s medical history and the availability of donor organs, to determine the best course of treatment for the individual. In some cases, the transplant may be postponed or the recipient may be treated with medications to reduce their antibody levels before the transplant can take place.