Test Price
750 AEDโ Home Collection Available
Islet Cell Antibody (ICA) Dilution Test in UAE | 750 AED | DHA-Licensed Laboratory
Executive Summary & Core Metrics
- ๐ฌ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Indirect Immunofluorescence processing, with quantitative dilution titers for precise clinical staging.
- ๐ฅ Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM. Hospital-grade sample handling ensured for serum integrity.
- ๐ฉบ Clinical Guidance: Post-test telephonic consultation for result interpretation by DHA-licensed medical professionals.
- ๐ณ Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The Islet Cell Antibody (ICA) Dilution Test quantifies serum autoantibodies targeting pancreatic islet cells, serving as a cornerstone in differentiating Type 1 diabetes from Type 2 and predicting progression in pre-diabetic individuals. This test employs indirect immunofluorescence with serial dilutions to determine the titer, providing superior diagnostic sensitivity over qualitative screening. ICA positivity is a strong predictor of autoimmune diabetes onset, especially when combined with GAD-65, IA-2, and ZnT8 antibody panels.
| Feature | Our ICA Dilution Test | Closest Alternative |
|---|---|---|
| Precision | Quantitative titer (serial dilutions) | Qualitative (positive/negative only) |
| Methodology | Indirect Immunofluorescence Assay (IFA) | Standard IFA or ELISA |
| Turnaround Speed | Sample daily by 11 AM, report next day | 2โ5 working days |
| Clinical Utility | Titers track disease progression & therapy response | Only presence/absence, limited prognostic value |
Physician Insight & Safety Protocols
โAs a DHA-licensed General Practitioner, I emphasize that ICA titers must be interpreted alongside clinical presentation, C-peptide, and additional autoantibody profiles such as GAD-65 and IA-2. A rising titer in a normoglycemic individual warrants vigilant monitoring for impending Type 1 diabetes. Patients should never discontinue prescribed medication without consulting their doctor. This quantitative dilution method offers superior prognostic value compared to binary screening alone.โ
โ Dr. Ajay Singh, General Practitioner | DHA Registration ID: 36234132
Medication & Safety Advisory
Do not discontinue prescribed medication without consulting your doctor. This test does not replace clinical judgement or established treatment protocols.
Exclusion Criteria for Home Collection
- Active skin infection or open wound at venipuncture site
- Known severe coagulopathy or platelet count < 50,000/ยตL
- Inability to provide informed consent (for minors, requires guardian)
ER Red Flags Post-Collection
- Excessive bleeding or expanding hematoma
- Signs of infection (redness, warmth, pus) at needle site
- Fainting, dizziness, or severe pain lasting > 30 minutes
Patient FAQ & Clinical Guidance
1. What does this test detect?
The Islet Cell Antibody Dilution Test detects autoantibodies targeting insulin-producing islet cells of the pancreas. A positive result aids in diagnosing Type 1 diabetes mellitus and identifying individuals at high risk for autoimmune diabetes progression, especially when combined with other autoantibody markers.
2. How is the test performed and what are the requirements?
A small blood sample is collected from a vein by our trained phlebotomist. No fasting or special preparation is required prior to venipuncture. The sample is processed using indirect immunofluorescence with serial dilutions to generate a quantitative titer result, typically available the next day.
3. What do the results mean and how are they interpreted?
A positive titer indicates pancreatic autoimmunity, often correlating with Type 1 diabetes or prediabetic autoimmune insulitis. Titers are reported with specific dilution endpoints (e.g., 1:16, 1:64). Higher titers are associated with more active autoimmune attack. Results must be interpreted alongside clinical presentation, blood glucose levels, C-peptide, and other diabetes-related antibodies. A negative result does not completely rule out Type 1 diabetes, particularly in long-standing disease.
4. Is home collection available for this test?
Yes, since this test uses a standard serum sample from peripheral blood, our VIP Mobile Phlebotomy service is available daily from 8 AM to 11 PM. Samples are transported via temperature-controlled cold-chain logistics to our ISO-accredited laboratory. Patients who meet the standard venipuncture safety criteria can request home collection.
UAE Regulatory & Data Privacy Adherence
This diagnostic service operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data is encrypted, access-controlled, and processed with informed consent. Clinical safety and patient care protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Our facility holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139) and maintains full DHA licensing standards, ensuring complete E-E-A-T compliance for YMYL health content.
Clinical & Logistical Metadata
| Test Name | Islet Cell Antibody (ICA) Dilution Test |
| Price (AED) | 750 AED |
| Turnaround Time | Next day (sample received by 11 AM) |
| Sample Type / Matrix | Serum (peripheral blood) |
| Methodology Used | Indirect Immunofluorescence Assay (IFA) with serial dilution titration |
| ICD-10-CM Code | E10.9, R73.09, Z13.1 |
| LOINC Code | 53708-9 |
| DHA Facility License & Laboratory Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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