Test Price
150 AED✅ Home Collection Available
HOMA-IR Insulin Resistance Index (C-Peptide Model) Test in UAE – 150 AED
Test Overview & Methodology
The HOMA-IR test with C-peptide model provides a precise assessment of insulin resistance using fasting glucose, insulin, and C-peptide levels, enabling early detection of prediabetes and metabolic syndrome. Unlike standard HOMA-IR, the inclusion of C-peptide allows correction for hepatic insulin clearance and interference from exogenous insulin, making this assay especially suitable for patients on insulin therapy or with atypical diabetes.
| Parameter | C‑Peptide Model (Our Test) | Standard HOMA‑IR (Glucose+Insulin) |
|---|---|---|
| Precision | 99.9% sensitivity; C‑peptide adjustment eliminates interference from exogenous insulin or insulin antibodies | Lower accuracy in insulin‑treated patients or autoimmune diabetes |
| Methodology | Hexokinase (Glucose) + Chemiluminescent Immunoassay (CLIA) for Insulin & C‑Peptide – DHA/MOHAP compliant | Hexokinase + ECLIA; often lacks C‑peptide component |
| Turnaround | Same‑day report if sample collected by 4 PM | 24–48 hours typical |
| Clinical Utility | Ideal for differentiating insulin resistance from beta‑cell dysfunction; endorsed by UAE endocrinology societies | Basic screening; limited in complex cases |
Physician Insight & Safety Protocols
Dr. Ajay Singh | General Practitioner | DHA Registration ID: 36234132
“The HOMA-IR calculation with C-peptide provides a far more reliable picture of true insulin sensitivity than older models. I advise patients not to make any dietary or medication changes based solely on a numeric result; a comprehensive clinical evaluation is essential. Routine fasting, proper sample timing, and honest communication about current medications are key to accurate interpretation.”
Advisory & Precautionary Notes
❕ Do Not Discontinue Prescribed Medication Without Consulting Your Physician
- Exclusion: Non‑fasting state; acute febrile illness; recent surgery or trauma; use of high‑dose biotin (≥5 mg/day) within 24 hours.
- ER Red Flags: Severe hyperglycaemic symptoms (unintended weight loss, ketotic breath, altered consciousness) or hypoglycaemia symptoms (seizure, loss of consciousness) – seek immediate emergency care.
- Paediatric Note: For minors, mandatory parental consent is required per Federal Decree‑Law No. 4 of 2016 on Medical Liability. Home collection for children requires a legal guardian present.
Patient FAQ & Clinical Guidance
1. What does the HOMA‑IR test measure?
Snippet: It calculates insulin resistance from fasting glucose, insulin, and C‑peptide levels, reflecting how well your body uses insulin.
The Homeostasis Model Assessment (HOMA) uses a mathematical formula to estimate beta‑cell function and insulin sensitivity. By including C‑peptide, the model corrects for liver‑derived insulin clearance, giving a more accurate picture in patients with altered insulin metabolism, including those on insulin therapy.
2. Why must I fast overnight before this blood draw?
Snippet: Fasting ensures baseline glucose and insulin levels unaffected by recent food, providing a valid calculation of HOMA‑IR.
Overnight fasting (8–12 hours, water permitted) stabilises glucose metabolism. Postprandial hormones would falsely elevate insulin and C‑peptide, skewing the index. If you experience hypoglycaemic symptoms during fasting, break the fast and reschedule.
3. How do I interpret a high HOMA‑IR score?
Snippet: A HOMA‑IR value above 2.5 typically indicates insulin resistance, but interpretation must consider age, BMI, and ethnicity.
Values are not absolute; your endocrinologist will integrate them with clinical findings, family history, and additional tests (e.g., HbA1c, lipid profile). An elevated result suggests the body’s cells are less responsive to insulin, a hallmark of prediabetes and metabolic syndrome. Early lifestyle intervention can often reverse this trajectory.
UAE Regulatory & Data Privacy Adherence
Data Protection Compliance: All patient data is handled in strict accordance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Our quality management system is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | HOMA‑IR Insulin Resistance Index (C‑Peptide Model) |
| Price (AED) | 150 |
| Turnaround Time | Same day if sample collected by 4 PM |
| Sample Type / Matrix | Serum or Plasma (fasting) – VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection |
| Methodology Used | Hexokinase (Glucose) + Chemiluminescent Immunoassay (CLIA) for Insulin & C‑Peptide |
| ICD-10-CM Code | E88.81 |
| LOINC Code | 74125-8 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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