Test Price
2,800 AED✅ Home Collection Available
NAGS Gene (N-Acetylglutamate Synthase) Deficiency Genetic Test in UAE | 2,800 AED | DHA Licensed
Executive Summary & Core Metrics
- 99.9% Diagnostic Sensitivity – ISO‑certified NGS with orthogonal confirmation protocols.
- Premium Logistics: Hospital‑grade home collection via cold‑chain transport, available 8 AM – 11 PM (VIP phlebotomy).
- Clinical Guidance: Post‑test telephonic interpretation by a DHA‑licensed genetic counsellor included.
- Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The NAGS Genetic Test utilises Next‑Generation Sequencing to detect pathogenic mutations in the N‑acetylglutamate synthase gene that impair the urea cycle and cause life‑threatening hyperammonemia. This assay is critical for early newborn screening, family risk assessment, and proactive metabolic health management.
| Feature | Our NAGS NGS Test | Standard Biochemical / Sanger |
|---|---|---|
| Methodology | Next‑Generation Sequencing (full gene coverage) | Enzyme assay or single‑exon Sanger |
| Turnaround Time | 3 – 4 weeks | 4 – 6 weeks (often requiring repeat samples) |
| Clinical Sensitivity | >99.9% for all reported point mutations and CNVs | ~85% (limited to common variants) |
| ISO Accreditation | ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) | Variable |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics, I emphasise that this NGS test provides definitive molecular diagnosis for NAGS deficiency. However, clinical correlation with ammonia levels, plasma amino acids, and metabolic status is mandatory. A negative result does not rule out other urea cycle disorders; ongoing consultation with a metabolic specialist is essential.”
— Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
Critical Advisory & Medication Safety
Medication Warning:
Do not discontinue any prescribed ammonia‑lowering therapy, carglumic acid, or dietary modifications without consulting your managing specialist. This test is a diagnostic aid, not a substitute for ongoing treatment.
Exclusion Criteria for Sample Collection
- Samples that are clotted, hemolyzed, or drawn >48 hours before arrival; FTA cards contaminated with chemicals.
- Active severe infection or acute metabolic decompensation – clinical stabilisation required prior to elective genetic testing.
- If the patient (especially infant) develops sudden lethargy, projectile vomiting, seizures, or coma – seek emergency medical care immediately, regardless of test status.
- A detailed three‑generation pedigree and formal genetic counselling must be completed before testing.
Patient FAQ & Clinical Guidance
1. What is NAGS gene deficiency and who should be tested?
NAGS deficiency is a rare autosomal recessive urea cycle disorder that prevents safe ammonia detoxification, leading to hyperammonemia; testing is indicated for newborns with unexplained lethargy, vomiting, and developmental delay, as well as for siblings and family planning carriers.
2. How is the test performed and what is the turnaround time?
The test requires a simple blood sample collected on an FTA card or EDTA tube, subjected to full NGS analysis of the NAGS gene, with results typically delivered within 3 to 4 weeks from sample receipt.
3. Is home sample collection available in Dubai and how do I schedule?
Yes, our DHA‑licensed phlebotomists perform hospital‑grade home collection across Dubai and Northern Emirates from 8 AM to 11 PM; simply send your Emirates ID and referral via WhatsApp to +971 54 548 8731 for instant confirmation and insurance pre‑approval.
UAE Regulatory & Data Privacy Adherence
- Full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Clinical testing safety and patient consent governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
- All genetic data processed on encrypted servers with zero cross-border transfer without explicit consent.
- ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | NAGS Gene (N-Acetylglutamate Synthase) Deficiency Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 – 4 weeks |
| Sample Type / Matrix | Whole blood (FTA card or EDTA tube) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM – 11 PM |
| Methodology Used | Next-Generation Sequencing (full gene coverage) |
| ICD-10-CM Code | E72.29, E72.2, Z13.79 |
| LOINC Code | 79353-1 |
| DHA Facility License & Laboratory Address | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians