Test Price
2,800 AED✅ Home Collection Available
NAGS Gene (N-Acetylglutamate Synthase) Deficiency Genetic Test in UAE | 2,800 AED | 2026 DHA Guidelines
تحليل جين NAGS (نقص N-أسيتيل غلوتامات سينثاز) في الإمارات | 2,800 درهم | معتمد من هيئة الصحة بدبي 2026
Executive Summary – الملخص التنفيذي
- 99.9% Diagnostic Sensitivity – ISO‑certified NGS with orthogonal confirmation protocols, compliant with 2026 DHA genomic requirements.
- Premium Logistics: Hospital‑grade home collection via cold‑chain transport, available 8 AM – 11 PM (VIP phlebotomy).
- Clinical Guidance: Post‑test telephonic interpretation by a DHA‑licensed genetic counsellor included.
- Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
ملخص تنفيذي: نقص جين NAGS هو اضطراب نادر في دورة اليوريا يُكشف عنه بواسطة التسلسل الجيني المتقدم بدقة تشخيصية 99.9%. مختبرنا المعتمد آيزو في دبي يقدم خدمة سحب منزلي مع نقل مبرد وإرشاد هاتفي بعد الفحص.
Comprehensive Overview
The NAGS Genetic Test utilises Next‑Generation Sequencing to detect pathogenic mutations in the N‑acetylglutamate synthase gene that impair the urea cycle and cause life‑threatening hyperammonemia. This assay is critical for early newborn screening, family risk assessment, and proactive metabolic health management. يكشف هذا الاختبار الجيني المتطور عن الطفرات المسببة لاضطراب دورة اليوريا الناتج عن نقص إنزيم N-أسيتيل غلوتامات سينثاز.
| Feature | Our NAGS NGS Test | Standard Biochemical / Sanger |
|---|---|---|
| Methodology | Next‑Generation Sequencing (full gene coverage) | Enzyme assay or single‑exon Sanger |
| Turnaround Time | 3 – 4 weeks | 4 – 6 weeks (often requiring repeat samples) |
| Clinical Sensitivity | >99.9% for all reported point mutations and CNVs | ~85% (limited to common variants) |
| ISO Accreditation | ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) | Variable |
Physician Insight & Safety Protocol
Dr. PRABHAKAR REDDY, DHA License: 61713011
“As a clinical geneticist, I want to reassure families that this test provides unparalleled clarity, but results must always be correlated with ammonia levels, plasma amino acids, and clinical presentation. A negative NGS result does not exclude other inborn errors of metabolism; please maintain close follow‑up with your metabolic physician.”
⚠️ Medication Warning: Do not discontinue any prescribed ammonia‑lowering therapy, carglumic acid, or dietary modifications without consulting your managing specialist.
Critical Safety & Exclusion Criteria
- Exclusion: Samples that are clotted, hemolyzed, or drawn >48 hours before arrival; FTA cards contaminated with chemicals.
- Exclusion: Active severe infection or acute metabolic decompensation – clinical stabilisation required prior to elective genetic testing.
- ER Red Flags: If the patient (especially infant) develops sudden lethargy, projectile vomiting, seizures, or coma – seek emergency medical care immediately, regardless of test status.
- Pre‑Test Requirement: A detailed three‑generation pedigree and formal genetic counselling must be completed.
Patient FAQ & Clinical Guidance
What is NAGS gene deficiency and who should be tested?
NAGS deficiency is a rare autosomal recessive urea cycle disorder that prevents safe ammonia detoxification, leading to hyperammonemia; testing is indicated for newborns with unexplained lethargy, vomiting, and developmental delay, as well as for siblings and family planning carriers.
نقص جين NAGS هو اضطراب وراثي نادر في دورة اليوريا يمنع التخلص من الأمونيا، مما يستدعي الفحص للمواليد الجدد الذين يعانون من أعراض عصبية غير مفسرة وللتخطيط العائلي.
How is the test performed and what is the turnaround time?
The requires a simple blood sample collected on an FTA card or EDTA tube, subjected to full NGS analysis of the NAGS gene, with results typically delivered within 3 to 4 weeks from sample receipt.
يتم جمع عينة دم على بطاقة FTA أو أنبوبة EDTA وتحليلها بتقنية التسلسل الجيني الكامل، وتصدر النتائج خلال 3 إلى 4 أسابيع.
Is home sample collection available in Dubai and how do I schedule?
Yes, our DHA‑licensed phlebotomists perform hospital‑grade home collection across Dubai and Northern Emirates from 8 AM to 11 PM; simply send your Emirates ID and referral via WhatsApp to +971 54 548 8731 for instant confirmation and insurance pre‑approval.
نعم، نوفر خدمة السحب المنزلي بواسطة ممرضين مرخصين من هيئة الصحة في دبي والإمارات الشمالية من 8 صباحاً حتى 11 مساءً، راسلونا عبر واتساب مع الهوية الإماراتية والتحويلة للتأكيد الفوري.
UAE Legislative & Clinical Compliance
- Full adherence to Federal Decree‑Law No. 41 of 2024 (Art. 87), governing genetic testing, confidentiality, and informed consent.
- Strict compliance with CDS Law 2026 – parental/legal guardian consent mandatory for minors.
- Data processed under UAE PDPL, with encrypted servers and zero cross‑border transfer without explicit consent.
- Facility License: 9834453 – ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139). LOINC: 79353‑1 (NAGS gene sequencing).
- Top ICD‑10‑CM Codes (2026): E72.29 – Other disorders of urea cycle metabolism; E72.2 – Disorder of urea cycle metabolism, unspecified; Z13.79 – Encounter for screening for other suspected genetic disorders.
- Clinical intent mapped to specialists: General Physician (initial hyperammonemia work‑up), Medical & PhD Researchers (cohort validation), Anti‑Aging Specialists (preventive metabolic screening).
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التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians