What is the CD79B gene test used for?

This NGS-based genetic test examines the CD79B gene for disease-causing mutations that lead to agammaglobulinemia type 6, a primary immunodeficiency. It is essential for confirming the molecular diagnosis and guiding appropriate immunotherapy management.

What does the test methodology involve?

The test utilizes Next-Generation Sequencing (NGS) for comprehensive full-exon coverage and bioinformatics analysis. This provides high diagnostic precision compared to alternative methods like Sanger Sequencing.

Is genetic counselling included?

Yes, telephonic post-test genetic counselling is included in the service to help interpret the results and discuss implications for the patient and their family members.

Genetics → Inherited Immunodeficiency Disorders

Also known as: CD79B Gene for Agammaglobulinemia Type 6 (NGS)

Results: 15–21 Business Days Sample: Peripheral Whole Blood or FTA Card

Test Price

2,800 AED

✅ Home Collection Available

📋 Results in 15–21 Business Days

CD79B Gene Agammaglobulinemia Type 6, Autosomal Recessive Genetic Test in UAE | 2800 AED

Q: How long does it take to get the results?

Results are delivered within 15 to 21 business days. A genetic counselling session is included to explain the findings and their impact on family health.

Executive Summary & Core Metrics

Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Next-Generation Sequencing (NGS) Processing.
Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy. Available daily from 8 AM to 11 PM.
Clinical Guidance: Telephonic Post-Test Genetic Counselling included in the service for result interpretation.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

This advanced genetic test screens the CD79B gene for mutations responsible for autosomal recessive agammaglobulinemia type 6, a severe primary immunodeficiency characterized by absent B cells and low immunoglobulins. The test utilizes Next-Generation Sequencing (NGS) for comprehensive full-exon coverage and bioinformatics analysis, delivering high diagnostic precision.

Feature	Our CD79B NGS Test	Sanger Sequencing (Alternative)
Precision	>99.9% analytical sensitivity	~95% for single gene
Methodology	NGS with full exon coverage & advanced bioinformatics	Sanger dideoxy sequencing, limited to targeted regions
Turnaround	15–21 Business Days	4–6 weeks

Physician Insight & Safety Protocols

Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403) notes:

"Identifying a CD79B mutation via NGS confirms the molecular diagnosis of agammaglobulinemia type 6, but must be correlated with clinical and immunological findings. A negative NGS result still warrants broader genetic or immunological workup. I always advise post-test counselling to discuss implications for family members."

Advisory & Safety Protocol

⚠️ Medication Warning: Do not discontinue any prescribed immunoglobulin therapy or prophylactic antibiotics without consulting your physician.

Exclusion Criteria & Red Flags

Safety Exclusion Criteria & Red Flags:

Exclude individuals with acute febrile illness or active systemic infection until resolution.
Minors (<18 years) require consent from legal guardian, in compliance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
If experiencing severe respiratory distress, high fever >39°C, or signs of sepsis, proceed directly to emergency care; genetic testing is not emergent.

Patient FAQ & Clinical Guidance

1. What is the CD79B gene test, and why is it performed?

This NGS-based genetic test examines the CD79B gene for disease-causing mutations that lead to agammaglobulinemia type 6, a primary immunodeficiency characterized by absent B cells and low immunoglobulins. It is essential for confirming the molecular diagnosis and guiding appropriate immunotherapy management.

2. How is the sample collected, and is it painful?

A certified phlebotomist collects a small blood sample (3-5 mL) from a vein in your arm, or a painless finger-prick for an FTA card, all in the comfort of your home via our VIP Mobile Phlebotomy service.

3. What is the turnaround time, and will I receive counselling?

Results are delivered within 15 to 21 business days, and a genetic counselling session is included to explain the findings and their impact on family health.

UAE Regulatory & Data Privacy Adherence

This service is provided in strict adherence to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent protocols are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE is ISO 9001:2015 Certified.

Clinical & Logistical Metadata

Test Name	CD79B Gene for Agammaglobulinemia Type 6 (NGS)
Price (AED)	2,800
Turnaround Time	15–21 Business Days (3–4 weeks)
Sample Type / Matrix	Peripheral Whole Blood or FTA Card
Methodology Used	Next-Generation Sequencing (NGS), Full Exon Coverage with Bioinformatics
ICD-10-CM Code	D80.0
LOINC Code	21641-6
DHA Facility License & Laboratory Address	Facility License 1143 \| Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE \| DNA Labs UAE

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Preparation Required

["No specific fasting required", "Inform lab of any current medications"]

Medically Reviewed by Dr. Lina Osama Zaki Quteineh

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