IMMUNOPHENOTYPING BY FLOW CYTOMETRY KAPPA and LAMBDA LIGHT CHAINS Test
Test Cost: AED 910.0
Introduction
Immunophenotyping by flow cytometry is a laboratory test that analyzes and identifies different types of cells in a sample, such as blood or tissue, based on the expression of specific proteins on their surface. The Kappa and Lambda light chains test is a specific type of immunophenotyping test that focuses on the analysis of Kappa and Lambda light chains, which are components of immunoglobulins (antibodies) produced by B cells.
Test Components
- Sample Condition: 3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tube AND 3 mL (2 mL min.) whole blood in 1 Green Top (Sodium Heparin) tube OR 2 mL (1 mL min.) Bone marrow in 1 Green Top (Sodium heparin) tube. Ship immediately at 18-22°C. DO NOT REFRIGERATE OR FREEZE. Specify time, date, and clinical details on the test request form.
Report Delivery
Sample Daily by 9 am; Report Same day
Method
Flow Cytometry
Test Type
Cancer
Doctor
Oncologist, Hematologist
Test Department
FLOW CYTOMETRY
Pre Test Information
Give brief clinical history.
Test Details
The Kappa and Lambda light chains test aims to determine the ratio of Kappa to Lambda light chains in B cells, helping to diagnose and monitor diseases such as lymphomas or multiple myeloma. Abnormal results in the Kappa and Lambda light chains test may indicate a clonal expansion of B cells, which can be indicative of a lymphoma or multiple myeloma. Further diagnostic tests, such as bone marrow biopsy or genetic analysis, may be necessary to confirm the diagnosis and determine the specific subtype of the disease.
Test Name | IMMUNOPHENOTYPING BY FLOW CYTOMETRY KAPPA and LAMBDA LIGHT CHAINS Test |
---|---|
Components | |
Price | 910.0 AED |
Sample Condition | 3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tubeAND 3 mL (2 mL min.) whole blood in 1 Green Top (Sodium Heparin) tube OR 2 mL (1 mL min.) Bone marrow in 1 Green Top (Sodium heparin) tube. Ship immediately at 18\u0192??22?\u00f8C. DO NOT REFRIGERATE OR FREEZE. Specify time, date and clinical details on test request form. |
Report Delivery | Sample Daily by 9 am; Report Same day |
Method | Flow Cytometry |
Test type | Cancer |
Doctor | Oncologist, Hematologist |
Test Department: | FLOW CYTOMETRY |
Pre Test Information | Give brief clinical history. |
Test Details | Immunophenotyping by flow cytometry is a laboratory test that is used to analyze and identify different types of cells in a sample, such as blood or tissue, based on the expression of specific proteins on their surface. The Kappa and Lambda light chains test is a specific type of immunophenotyping test that focuses on the analysis of Kappa and Lambda light chains, which are components of immunoglobulins (antibodies) produced by B cells. In normal conditions, B cells produce immunoglobulins with a balanced ratio of Kappa and Lambda light chains. However, in certain diseases, such as lymphomas or multiple myeloma, this balance can be disrupted, leading to an overproduction or underproduction of one of the light chains. The Kappa and Lambda light chains test aims to determine the ratio of Kappa to Lambda light chains in B cells, helping to diagnose and monitor these diseases. The test involves staining the cells with fluorescently-labeled antibodies specific to Kappa and Lambda light chains, and then analyzing them using flow cytometry. By comparing the fluorescence intensity of Kappa and Lambda, the test can determine the ratio of these light chains in the cells. Abnormal results in the Kappa and Lambda light chains test may indicate a clonal expansion of B cells, which can be indicative of a lymphoma or multiple myeloma. Further diagnostic tests, such as bone marrow biopsy or genetic analysis, may be necessary to confirm the diagnosis and determine the specific subtype of the disease. |