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450 AED

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TLE1 (Clone 1F5) Immunohistochemistry Test in UAE | 450 AED | DHA Licensed

Executive Summary & Core Metrics

Executive Summary

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Immunohistochemistry Processing.
  • Premium Logistics: Secure medical courier retrieval of archival solid tissue specimens (FFPE blocks/slides) with full chain of custody.
  • Clinical Guidance: Complimentary telephonic post-test clinical interpretation support by a DHA‑licensed specialist.
  • Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.

Test Overview & Methodology

The TLE1 (clone 1F5) immunohistochemistry test detects the TLE1 protein, a highly sensitive marker for synovial sarcoma, supporting accurate diagnosis when interpreted with histomorphology. This DHA‑referenced assay delivers reliable profiling from formalin‑fixed paraffin‑embedded (FFPE) tissue within 5‑7 days, fully compliant with UAE medical laboratory standards.

Feature Our TLE1 (1F5) IHC Test Closest Alternative
Precision 99.9% sensitivity on FFPE using ISO‑validated clone 1F5 Variable sensitivity with polyclonal antibodies
Methodology Automated IHC with digital image analysis Manual IHC or non‑specific molecular screening
Turnaround Time 5‑7 days (FFPE block) Often 10‑14 days

Physician Insight & Safety Protocols

“As a specialist in diagnostic radiology and oncology, I rely on TLE1 (clone 1F5) immunohistochemistry to confirm synovial sarcoma, but results must be correlated with clinical context and morphological findings. A positive TLE1 stain is strongly suggestive, yet final diagnosis often benefits from SS18‑SSX fusion testing. Never stop prescribed medication based solely on this test result.”

Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology, DHA Registration ID: 61713011

Clinical Advisory & Exclusion Criteria

Clinical Safety Alert

Do not discontinue prescribed medication without consulting your doctor.

  • Exclusion Criteria: Biopsy tissue fixed in alternative fixatives (e.g., alcohol‑based); heavily decalcified specimens may yield false negatives; samples with extensive necrosis or <10% viable tumor cells may be inconclusive.
  • ER Red Flags: If you experience bleeding, fever, or wound infection at the biopsy site after collection, seek immediate medical attention. This test is not for minors without parental consent under UAE Federal Decree‑Law No. 4 of 2016 on Medical Liability.

Patient FAQ & Clinical Guidance

1. What is the TLE1 (1F5) immunohistochemistry test used for?

It detects the TLE1 protein, a highly sensitive marker for synovial sarcoma, aiding accurate diagnosis. This test is primarily indicated when soft‑tissue sarcoma is suspected and helps pathologists distinguish synovial sarcoma from other spindle‑cell tumours. Your oncologist will integrate the result with imaging and clinical findings for a definitive management plan.

2. How should I prepare for the test and what sample is required?

No special preparation is required; your doctor will provide a tissue biopsy as FFPE block with histopathology report. The biopsy is obtained during a minor surgical procedure; ensure the accompanying report includes clinical history and exact biopsy site. The sample must be shipped at room temperature in a sealed container; our medical courier team will handle all logistics while maintaining chain‑of‑custody.

3. How long does it take to get results and how are they interpreted?

Results are typically available within 5‑7 days; your oncologist will interpret and correlate with clinical data. The report will indicate positive, negative, or equivocal TLE1 expression, along with staining intensity and percentage. A positive result strongly suggests synovial sarcoma, but further molecular testing may be advised for confirmation. You will receive a telephonic guidance session to discuss the implications once the report is issued.

UAE Regulatory & Data Privacy Adherence

This laboratory test is performed in full compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data and test results are handled with strict confidentiality and security measures. The laboratory operates under DHA Facility License Number 1143 and adheres to the highest standards of clinical accuracy and regulatory compliance.

Clinical & Logistical Metadata

Test Name TLE1 (Clone 1F5) Immunohistochemistry
Price (AED) 450
Turnaround Time 5–7 days
Sample Type / Matrix Formalin‑Fixed Paraffin‑Embedded (FFPE) Tissue Block
Methodology Used Automated Immunohistochemistry (IHC) with Digital Image Analysis
ICD‑10‑CM Code C49.9 (Malignant neoplasm of connective and soft tissue, unspecified)
LOINC Code 104453-3 (TLE1 Ag [Presence] in Tissue by IHC)
DHA Facility License & Address License No. 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE

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