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450 AED

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S100 Immunohistochemistry Test in Dubai | 450 AED | DNA Labs UAE

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
  • Secure Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval for archival FFPE blocks and biopsy slides.
  • Clinical Guidance: Complimentary Telephonic Post-Test Clinical Guidance in Result Interpretation.
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The S100 Immunohistochemistry (IHC) Test identifies S100 protein expression in formalin-fixed paraffin-embedded (FFPE) tissue or biopsy specimens, serving as a critical diagnostic tool for differentiating melanoma, schwannoma, and various mesenchymal tumors. The assay employs standardized antigen retrieval with validated monoclonal antibodies on automated IHC platforms, ensuring reproducible results across all tissue types.

Feature Our S100 IHC Test Closest Alternative
Diagnostic Precision 99.9% Sensitivity, ISO 9001:2015 Certified Variable, non-standardized reporting
Methodology Advanced IHC with standardized antigen retrieval Conventional IHC without QA protocols
Turnaround Time 5–7 working days for complex tissue 7–10 days

Physician Insight & Safety Protocols

“S100 immunoreactivity must be interpreted within the full morphologic and clinical context. A spindle cell neoplasm positive for S100 may require additional markers such as Melan-A or SOX-10 to definitively confirm melanoma. Correlation with histologic features is non-negotiable prior to final diagnosis.”

— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology (DHA Registration ID: 61713011)

Advisory & Safety Precautions

⚠️ Important Notice: This test does not replace a comprehensive clinical evaluation by your treating physician. Do not alter or discontinue any prescribed therapy without direct consultation with your healthcare provider. The immunohistochemical findings must be integrated with the complete histopathologic assessment.

Exclusion Criteria & Patient Safety

  • Specimen Exclusion: Inadequate tissue sample (insufficient size, extensive necrosis) or improper fixation using non-formalin-based fixatives renders the specimen unsuitable for IHC analysis.
  • Emergency Red Flag: Rapid tumor enlargement, surface ulceration, or active bleeding associated with the lesion requires immediate emergency evaluation.
  • Pediatric Consent: For minors under 18 years, mandatory written consent from a parent or legal guardian is required per Federal Decree-Law No. 4 of 2016 on Medical Liability.
  • Data Privacy: All specimens are processed in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.

Patient FAQ & Clinical Guidance

1. What is an S100 immunohistochemistry test and why is it ordered?

The S100 IHC test is a specialized staining procedure that detects S100 protein expression in tissue specimens. It is ordered when a pathologist needs to differentiate melanocytic neoplasms (such as melanoma), peripheral nerve sheath tumors (such as schwannoma), and certain sarcomas from other spindle cell lesions. The result guides oncologic treatment planning and prognostic assessment.

2. Why must I provide my histopathology report and clinical history?

The histopathology report and clinical history are mandatory because accurate interpretation of S100 staining patterns depends entirely on morphologic correlation. Without prior H&E slides and relevant clinical data (age, lesion site, growth pattern), the IHC result cannot be rendered clinically actionable.

3. How is the sample collected and what is the delivery timeline?

Sample collection requires a tumor tissue specimen obtained via biopsy or surgical excision, preserved as a formalin-fixed paraffin-embedded (FFPE) block or unstained slides. All archival tissue specimens are retrieved via Secure Medical Courier Solid Tissue Specimen Retrieval. Reports are delivered within 5–7 working days from receipt of adequate tissue.

4. Will my insurance cover the cost of the S100 IHC test?

Coverage varies by insurance provider and policy. DNA Labs UAE offers direct billing verification via WhatsApp at +971 54 548 8731. Our billing team can check your eligibility and provide an upfront cost estimate prior to specimen submission.

UAE Regulatory & Data Privacy Adherence

Regulatory Compliance Framework: DNA Labs UAE operates under DHA Facility License Number 1143 (Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE). All laboratory testing adheres to ISO 9001:2015 quality management standards (Cert: INT/EGQ/2509DA/3139). Patient data handling strictly follows Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Specimen handling and clinical consent procedures comply with Federal Decree-Law No. 4 of 2016 on Medical Liability.

Clinical & Logistical Metadata

Test Name S100 Immunohistochemistry (IHC) Test
Price (AED) 450
Turnaround Time 5–7 working days
Sample Type / Matrix FFPE Tissue Block or Unstained Biopsy Slides
Methodology Used Immunohistochemistry (IHC) with standardized antigen retrieval and automated staining platform
ICD-10-CM Code C43.9
LOINC Code 10462-5
DHA Facility License & Address License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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