Test Price
1,500 AED✅ Home Collection Available
PD-L1 SP142 Immunohistochemistry Test in UAE | 1500 AED
Executive Summary & Core Metrics
- ✓Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified IHC Protocols, validated against international proficiency standards.
- ✓Premium Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval (Archival) – FFPE tissue blocks and slides collected via temperature-controlled courier; express drop-off available.
- ✓Clinical Guidance: Complimentary Post-Test Telephonic Consultation with a DHA-Licensed Specialist to interpret your PD-L1 status and next steps.
- ✓Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731. We work with major UAE networks.
Test Overview & Methodology
The PD-L1 SP142 Immunohistochemistry Test semi‑quantitatively measures programmed death‑ligand 1 expression on tumor cells and tumour‑infiltrating immune cells. This clone‑specific assay is pivotal for identifying patients who may benefit from atezolizumab (Tecentriq) immunotherapy, particularly in non‑small cell lung cancer, urothelial carcinoma, and triple‑negative breast cancer. The results provide a dual score (TC and IC) used by oncologists to tailor personalized treatment plans.
| Feature | Our Test (SP142 IHC) | Alternative (Standard IHC, 22C3/28-8) |
|---|---|---|
| Clinical Precision | Specifically validated for atezolizumab; dual scoring (TC & IC) | Primarily scored for pembrolizumab/nivolumab; single TC scoring |
| Methodology | Immunohistochemistry with SP142 antibody clone, ISO‑accredited | IHC using different clones (22C3, 28-8); variable lab accreditation |
| Report Turnaround | 5–7 working days (Faster for FFPE blocks) | Often 7–10 days |
Physician Insight & Safety Protocols
A clinical note from Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology (DHA Registration ID: 61713011): “As a DHA-licensed diagnostic radiologist with deep experience in oncology imaging and biomarker interpretation, I understand the importance of this assay. PD-L1 SP142 IHC provides a critical piece of your personalized treatment puzzle, but it must be interpreted within the full clinical picture. I strongly recommend that you discuss these results with your treating oncologist before initiating or modifying any therapy.”
Medication Advisory
Do not discontinue prescribed medication or alter your treatment plan without consulting your doctor. This test is a diagnostic aid and should not replace professional medical judgment.
Safety Exclusion Criteria & ER Red Flags
- Exclusion: Severe coagulopathy, active infection at the biopsy site, or inability to provide adequate tissue sample.
- Exclusion: Patients who cannot safely discontinue anticoagulants per physician instruction (if required for biopsy).
- ER Red Flag: Seek urgent medical attention if you experience fever >38°C, unrelenting pain, or pus/discharge at the biopsy site after the procedure.
- ER Red Flag: Rapid swelling or bleeding that does not stop with gentle pressure.
Patient FAQ & Clinical Guidance
1. What is PD-L1 SP142 testing and why is it performed?
PD-L1 SP142 immunohistochemistry evaluates tumor PD-L1 expression to predict response to atezolizumab immunotherapy in advanced cancers. This provides a quantitative score (TC and IC) that oncologists use to determine eligibility for targeted treatment, improving the chance of a positive outcome.
2. How should I prepare for the biopsy and sample submission?
No special patient preparation is needed, but you must arrange for a fresh tumor biopsy or FFPE block, provide a copy of your histopathology report, and note your biopsy site and relevant clinical history. Our secure courier service will transport the sample under strict cold‑chain protocols.
3. When will I receive my results and who will explain them?
Routine FFPE block reports are ready in 5 working days; large complex specimens take up to 7 days. A complimentary telephonic consultation with a DHA-licensed specialist is included to guide you through the PD-L1 scoring and its therapeutic implications.
UAE Regulatory & Data Privacy Adherence
Data Protection & Health Information Governance: All patient data is handled in strict adherence to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
Accreditation: ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).
For insurance verification or sample collection booking, WhatsApp +971 54 548 8731 (8 AM – 11 PM daily).
Clinical & Logistical Metadata
| Test Name | PD-L1 SP142 Immunohistochemistry Test |
| Price (AED) | 1,500 |
| Turnaround Time | 5–7 working days |
| Sample Type / Matrix | FFPE tissue block or biopsy slide (Archival Solid Tissue) |
| Methodology Used | Immunohistochemistry (IHC) with SP142 antibody clone |
| ICD-10-CM Code | Z85.118 |
| LOINC Code | 90512-7 |
| DHA Facility License & Laboratory Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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