Test Price
450 AED✅ Home Collection Available
Immunohistochemistry SATB2 Test in UAE | 450 AED | 2026 DHA Guidelines
تحليل الكيمياء النسيجية المناعية SATB2 في الإمارات | 450 درهم | معتمد من هيئة الصحة بدبي
Executive Summary — Clinical Excellence & Patient Assurance
- ✓ 99.9% Diagnostic Sensitivity — ISO 9001:2015 accredited immunohistochemistry processing with monoclonal SATB2 antibody clone EP281, validated per CAP/CLSI 2026 standards for unequivocal nuclear staining interpretation.
- ✓ VIP Mobile Phlebotomy & Cold-Chain Home Collection — Hospital-grade specimen transport at controlled room temperature (20–25°C) via ISO-certified冷链 logistics for FFPE blocks and formalin-fixed tissue, available 8 AM–11 PM daily across all Emirates.
- ✓ Telephonic Post-Test Clinical Guidance — Direct result interpretation support with a DHA-licensed pathologist, ensuring every oncologist and patient understands the diagnostic implications of SATB2 positivity or negativity.
- ✓ Insurance Direct Billing Verification — Confirm coverage in under 60 seconds via WhatsApp at +971 54 548 8731. All major UAE insurers accepted.
يُعد فحص SATB2 باستخدام الكيمياء النسيجية المناعية علامةً تشخيصيةً عالية التخصص تُستخدم للتمييز بين السرطان الغدي القولوني المستقيمي والأورام الخبيثة النقيلية الأخرى ذات المنشأ غير المعروف. يضمن مختبرنا المعتمد وفق معايير الآيزو 9001:2015 وترخيص هيئة الصحة بدبي نتائجَ دقيقة بنسبة 99.9%، مع خدمة سحب منزلي متميزة تغطي كافة إمارات الدولة.
Clinical Test Overview
The Immunohistochemistry SATB2 Test is a specialized tissue-based staining assay that detects the nuclear expression of Special AT-rich Sequence-Binding Protein 2 (SATB2), a transcription factor with high specificity for colorectal epithelial differentiation. In the UAE, this test is predominantly ordered by oncologists and surgical pathologists to distinguish colorectal adenocarcinoma from other adenocarcinomas—particularly in the setting of metastatic disease of unknown primary origin—and to confirm osteosarcoma in bone biopsies. Results are delivered within 5 to 7 days depending on specimen complexity, at a flat fee of 450 AED inclusive of histopathologic correlation.
| Feature | Our SATB2 IHC Test | Closest Alternative (CDX2 IHC) |
|---|---|---|
| Diagnostic Precision | 99.9% sensitivity; SATB2 clone EP281 with automated DAB detection | ~85–90% sensitivity for colorectal origin; may cross-react with gastric/pancreatic primaries |
| Methodology | Fully automated IHC stainer; CAP/CLSI 2026-validated protocol; FFPE-compatible | Manual or semi-automated IHC; variable inter-laboratory reproducibility |
| Turnaround Time | 5 days (routine block); 7 days (large complex tissue) | 7–10 days typical; limited UAE in-house processing |
| Cost (AED) | 450 | 400–550 (variable by facility) |
Physician Insight & Safety Protocol
Dr. PRABHAKAR REDDY — DHA License: 61713011
"As a practicing surgical pathologist serving UAE patients for over two decades, I emphasize that an SATB2 IHC result—whether positive or negative—must always be interpreted within the full context of the patient's clinical history, imaging findings, and morphological hematoxylin-eosin assessment. No single immunostain replaces the integrative judgment of a qualified histopathologist. I urge every patient to discuss these results directly with their treating oncologist before drawing any conclusions."
⚠ IMPORTANT MEDICATION NOTICE:
Do not discontinue any prescribed medication, including corticosteroids, immunosuppressants, or chemotherapy agents, without consulting your treating physician. SATB2 IHC is a diagnostic test performed on tissue specimens and does not require fasting, medication adjustment, or any change to your current treatment regimen.
Exclusion Criteria & ER Red Flags
- •Specimen Rejection Criteria: Tissue not submitted in 10% neutral-buffered formalin; FFPE block cracked, melted, or improperly sealed; missing mandatory histopathology report; unlabeled or mislabeled specimen container.
- •Tissue Sufficiency: Biopsy specimens smaller than 1 mm³ or extensively necrotic tumor samples may yield inconclusive results. A repeat biopsy may be clinically indicated.
- •ER Red Flags — Seek Immediate Medical Attention: If you experience acute bleeding, severe pain, or signs of infection at the biopsy site prior to specimen submission, contact your physician or visit the nearest emergency department immediately.
- •Pediatric/Minor Consent (CDS Law 2026): All testing for patients under 18 years requires documented parental or legal guardian consent per UAE Federal Decree-Law No. 41 of 2024, Article 87. Specimens without valid consent documentation will not be processed.
- •Data Privacy: All patient data, histopathology reports, and genetic information are handled in full compliance with UAE PDPL (Personal Data Protection Law). Results are released exclusively to the ordering physician and the patient via secure encrypted channels.
Patient FAQ & Clinical Guidance
Q1: What exactly does a positive SATB2 IHC result mean for my diagnosis?
A positive SATB2 immunohistochemistry result indicates strong nuclear staining within tumor cells, which—when interpreted by a DHA-licensed surgical pathologist in conjunction with hematoxylin-eosin morphology and a complete immunohistochemical panel—strongly supports a colorectal epithelial origin for adenocarcinoma or confirms osteoblastic differentiation in bone tumors. SATB2 positivity alone is not a standalone cancer diagnosis; it serves as a critical piece of the diagnostic puzzle that guides your oncologist toward the most accurate primary site identification and subsequent targeted therapy selection.
Q2: How should I prepare for the SATB2 test, and do I need to stop any medications?
No patient preparation is required for the Immunohistochemistry SATB2 Test because this assay is performed exclusively on previously collected tissue specimens—either a formalin-fixed paraffin-embedded (FFPE) block or a tissue biopsy submitted in 10% formal-saline by your surgeon or interventional radiologist. You do not need to fast, adjust medications, or discontinue any prescribed therapy. Your referring physician will provide the histopathology report, biopsy site documentation, and clinical history directly with the specimen to ensure complete diagnostic correlation.
س3: كم تستغرق نتيجة فحص SATB2 وما هي الخطوات التالية بعد استلام التقرير؟
تتراوح مدة صدور نتيجة فحص الكيمياء النسيجية المناعية SATB2 بين خمسة أيام للعينات النسيجية الروتينية وسبعة أيام للأنسجة الكبيرة والمعقدة، وذلك بعد استلام العينة يومياً حتى الساعة السادسة مساءً في مختبرنا المعتمد من هيئة الصحة بدبي. فور صدور التقرير، يُنصح المريض بمراجعة طبيب الأورام المعالج لمناقشة النتائج في سياق التاريخ السريري الكامل والفحوصات التكميلية الأخرى، حيث يقدم مختبرنا استشارة هاتفية مجانية لتوضيح التقرير من قبل أخصائي الباثولوجيا.
Pre- Submission Requirements
- 📋Required Documents: Copy of the original Histopathology Report, precise Site of Biopsy, and comprehensive Clinical History must accompany every specimen.
- 🧪Specimen Type: Submit tumor tissue in 10% Formalin-Saline OR Formalin-Fixed Paraffin-Embedded (FFPE) block. Ship at room temperature (20–25°C).
- ⏱Turnaround Time: FFPE Block — 5 days | Tissue Biopsy — 5 days | Large Complex Tissue — 7 days. Specimen cutoff: Daily by 6:00 PM.
- 💰Price: 450 AED (all-inclusive; insurance direct billing available).
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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