Test Price
450 AED✅ Home Collection Available
Immunohistochemistry SATB2 Test – Dubai Healthcare City | 450 AED
Executive Summary & Core Metrics
- ✓ 99.9% Diagnostic Sensitivity — ISO 9001:2015 accredited immunohistochemistry processing with monoclonal SATB2 antibody clone EP281, validated per CAP/CLSI standards for unequivocal nuclear staining interpretation.
- ✓ Secure Medical Courier Solid Tissue Specimen Retrieval — Temperature-controlled transport for FFPE blocks and formalin-fixed tissue, available 8 AM–11 PM daily across all Emirates.
- ✓ Telephonic Post-Test Clinical Guidance — Direct result interpretation support with a DHA-licensed specialist, ensuring every oncologist and patient understands the diagnostic implications of SATB2 positivity or negativity.
- ✓ Insurance Direct Billing Verification — Confirm coverage in under 60 seconds via WhatsApp at +971 54 548 8731. All major UAE insurers accepted.
Test Overview & Methodology
The Immunohistochemistry SATB2 Test is a specialized tissue-based staining assay that detects the nuclear expression of Special AT-rich Sequence-Binding Protein 2 (SATB2), a transcription factor with high specificity for colorectal epithelial differentiation. In the UAE, this test is predominantly ordered by oncologists and surgical pathologists to distinguish colorectal adenocarcinoma from other adenocarcinomas—particularly in the setting of metastatic disease of unknown primary origin—and to confirm osteosarcoma in bone biopsies. Results are delivered within 5 to 7 days depending on specimen complexity, at a flat fee of 450 AED inclusive of histopathologic correlation.
Pre-Submission Requirements
- 📋Required Documents: Copy of the original Histopathology Report, precise Site of Biopsy, and comprehensive Clinical History must accompany every specimen.
- 🧪Specimen Type: Submit tumor tissue in 10% Formalin-Saline OR Formalin-Fixed Paraffin-Embedded (FFPE) block. Ship at room temperature (20–25°C).
- ⏱Turnaround Time: FFPE Block — 5 days | Tissue Biopsy — 5 days | Large Complex Tissue — 7 days. Specimen cutoff: Daily by 6:00 PM.
- 💰Price: 450 AED (all-inclusive; insurance direct billing available).
| Feature | Our SATB2 IHC Test | Closest Alternative (CDX2 IHC) |
|---|---|---|
| Diagnostic Precision | 99.9% sensitivity; SATB2 clone EP281 with automated DAB detection | ~85–90% sensitivity for colorectal origin; may cross-react with gastric/pancreatic primaries |
| Methodology | Fully automated IHC stainer; CAP/CLSI-validated protocol; FFPE-compatible | Manual or semi-automated IHC; variable inter-laboratory reproducibility |
| Turnaround Time | 5 days (routine block); 7 days (large complex tissue) | 7–10 days typical; limited UAE in-house processing |
| Cost (AED) | 450 | 400–550 (variable by facility) |
Physician Insight & Safety Protocols
Mr. Prabhakar Reddy Kalathoor — Specialist Diagnostic Radiology | DHA Registration ID: 61713011
"As a practicing diagnostic radiologist serving UAE patients for over two decades, I emphasize that an SATB2 IHC result—whether positive or negative—must always be interpreted within the full context of the patient's clinical history, imaging findings, and morphological hematoxylin-eosin assessment. No single immunostain replaces the integrative judgment of a qualified histopathologist. I urge every patient to discuss these results directly with their treating oncologist before drawing any conclusions."
Medication Advisory
⚠ Important Medication Notice
Do not discontinue any prescribed medication, including corticosteroids, immunosuppressants, or chemotherapy agents, without consulting your treating physician. SATB2 IHC is a diagnostic test performed on tissue specimens and does not require fasting, medication adjustment, or any change to your current treatment regimen.
Exclusion Criteria & Safety Red Flags
- •Specimen Rejection Criteria: Tissue not submitted in 10% neutral-buffered formalin; FFPE block cracked, melted, or improperly sealed; missing mandatory histopathology report; unlabeled or mislabeled specimen container.
- •Tissue Sufficiency: Biopsy specimens smaller than 1 mm³ or extensively necrotic tumor samples may yield inconclusive results. A repeat biopsy may be clinically indicated.
- •ER Red Flags — Seek Immediate Medical Attention: If you experience acute bleeding, severe pain, or signs of infection at the biopsy site prior to specimen submission, contact your physician or visit the nearest emergency department immediately.
- •Pediatric/Minor Consent: All testing for patients under 18 years requires documented parental or legal guardian consent per UAE Federal Decree-Law No. 4 of 2016 on Medical Liability. Specimens without valid consent documentation will not be processed.
- •Data Privacy: All patient data, histopathology reports, and genetic information are handled in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Results are released exclusively to the ordering physician and the patient via secure encrypted channels.
Patient FAQ & Clinical Guidance
1. What exactly does a positive SATB2 IHC result mean for my diagnosis?
A positive SATB2 immunohistochemistry result indicates strong nuclear staining within tumor cells, which—when interpreted by a DHA-licensed surgical pathologist in conjunction with hematoxylin-eosin morphology and a complete immunohistochemical panel—strongly supports a colorectal epithelial origin for adenocarcinoma or confirms osteoblastic differentiation in bone tumors. SATB2 positivity alone is not a standalone cancer diagnosis; it serves as a critical piece of the diagnostic puzzle that guides your oncologist toward the most accurate primary site identification and subsequent targeted therapy selection.
2. How should I prepare for the SATB2 test, and do I need to stop any medications?
No patient preparation is required for the Immunohistochemistry SATB2 Test because this assay is performed exclusively on previously collected tissue specimens—either a formalin-fixed paraffin-embedded (FFPE) block or a tissue biopsy submitted in 10% formal-saline by your surgeon or interventional radiologist. You do not need to fast, adjust medications, or discontinue any prescribed therapy. Your referring physician will provide the histopathology report, biopsy site documentation, and clinical history directly with the specimen to ensure complete diagnostic correlation.
3. How long does the SATB2 result take, and what are the next steps after receiving the report?
Turnaround time ranges from five days for routine tissue specimens to seven days for large or complex tissue samples, measured from specimen receipt at our DHA-licensed laboratory (daily cutoff at 6:00 PM). Once the report is issued, patients are advised to consult their treating oncologist to discuss results within the full clinical context. Our laboratory provides a complimentary telephonic consultation with a specialist pathologist to help clarify the report findings.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance: This diagnostic service is provided in full accordance with UAE Federal Decree-Law No. 4 of 2016 on Medical Liability, Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL), and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data, histopathology reports, and genetic information are processed through encrypted channels and released exclusively to the ordering physician and the patient.
Accreditation: ISO 9001:2015 Quality Management System — Certificate No. INT/EGQ/2509DA/3139. All laboratory processes are validated per CAP (College of American Pathologists) and CLSI guidelines.
Support: WhatsApp +971 54 548 8731 | Secure Courier Retrieval Available 8 AM – 11 PM Daily | All Emirates Covered.
Clinical & Logistical Metadata
| Test Name | Immunohistochemistry SATB2 Test |
| Price (AED) | 450 |
| Turnaround Time | 5–7 business days |
| Sample Type / Matrix | Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Block / Archival Tissue Specimen |
| Methodology Used | Automated Immunohistochemistry (IHC) – Monoclonal SATB2 Clone EP281 with DAB Chromogen Detection |
| ICD-10-CM Code | C18.9, C80.1, Z12.11 |
| LOINC Code | 94445-5 |
| DHA Facility License & Laboratory Address Invariants | DHA License No. 1143 | DNA Labs UAE | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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