Test Price
200 AED✅ Home Collection Available
Immunohistochemistry pS2 Test in UAE | 200 AED | DHA Licensed Laboratory
Executive Summary & Core Metrics
Clinical Accuracy
99.9% Diagnostic Sensitivity via ISO 15189:2012 Accredited Processing.
Specimen Retrieval
Secure Medical Courier Solid Tissue Specimen Retrieval for FFPE blocks or tissue biopsies.
Post-Test Tele-Guidance
Complimentary clinical interpretation call with DHA-licensed pathologist.
Insurance Verification
Direct Billing Check via WhatsApp: +971 54 548 8731
The pS2 Immunohistochemistry test is a high-precision tissue-based assay quantifying trefoil factor 1 (TFF1) expression in breast tumor specimens. This biomarker supports prognostic stratification and endocrine therapy decision-making, delivered under DHA-regulated quality standards at DNA Labs UAE.
Test Overview & Methodology
The Immunohistochemistry pS2 Test quantifies trefoil factor 1 protein expression in breast tumor tissue, a critical prognostic and predictive marker for estrogen receptor-positive carcinomas. Elevated pS2 indicates favorable response to endocrine therapy, guiding oncologists toward personalized treatment protocols while ruling out aggressive subtypes. The assay is performed on formalin-fixed paraffin-embedded (FFPE) tissue blocks or fresh biopsy specimens using automated digital image analysis for objective scoring.
| Feature | Our pS2 IHC Test | Alternative (ER/PR Only) |
|---|---|---|
| Methodology | Quantitative Immunohistochemistry + Automated Digital Image Analysis | Semi-quantitative light microscopy |
| Turnaround Time | 5–7 business days (FFPE Block) | 7–10 business days |
| Guideline Alignment | DHA/MOHAP & ASCO/CAP Standards | Varies, often outdated |
Physician Insight & Safety Protocols
“As a DHA-licensed specialist in diagnostic radiology, I emphasize that the pS2 result must be interpreted in the full context of histopathology, ER/PR/HER2 status, and clinical staging. It is a complementary tool, not a standalone diagnostic, and should never replace multidisciplinary tumor board review.” — Mr. Prabhakar Reddy Kalathoor, DHA Registration ID: 61713011
Important Advisory
- Do not discontinue any prescribed medication, especially hormone therapy, without consulting your oncologist.
- This test is not validated for pediatric patients (age <18) without explicit guardian consent in accordance with UAE medical liability regulations.
- Urgent symptoms (e.g., new palpable mass, acute pain, or discharge) require immediate clinical evaluation, not elective biomarker testing.
- Patients on anticoagulant therapy must inform the referring clinician; biopsy site healing must be confirmed before sample collection.
Exclusion Criteria
- Insufficient tissue volume or necrotic biopsy samples are not suitable for reliable pS2 IHC analysis.
- Specimens with prior chemical or decalcification processing may compromise antigen detection.
- Patients with known allergy to mouse monoclonal antibodies or detection system components should inform the laboratory.
Patient FAQ & Clinical Guidance
1. What exactly does the pS2 test measure in breast cancer?
The test measures the expression level of trefoil factor 1 protein, a marker associated with well-differentiated, hormone-responsive breast tumors that typically carry a more favorable prognosis.
2. What does a low pS2 level in my report indicate?
A low pS2 expression may suggest a more aggressive tumor phenotype or potential resistance to endocrine therapy. The finding must be discussed with your oncologist to formulate a tailored treatment plan.
3. Is home sample collection available for this test and is it reliable?
Yes, we provide ISO-certified cold-chain transport for FFPE blocks or tissue biopsies from your location; a DHA-licensed pathologist oversees the entire logistics chain to guarantee specimen integrity identical to in-lab collection.
UAE Regulatory & Data Privacy Adherence
Data Protection & Health Information Governance
DNA Labs UAE operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient health records, test results, and genomic data are encrypted, access-controlled, and processed exclusively within UAE data centers. Clinical safety and patient consent protocols follow Federal Decree-Law No. 4 of 2016 on Medical Liability to ensure ethical and legally compliant care delivery.
Our DHA-licensed facility (License No. 1143) maintains ISO 15189:2012 accreditation for laboratory quality management, with regular external audits to guarantee data integrity and diagnostic accuracy.
Clinical & Logistical Metadata
| Test Name | Immunohistochemistry pS2 (TFF1) – Breast Tumor Tissue |
| Price (AED) | 200 AED |
| Turnaround Time | 5–7 business days from receipt of FFPE block or biopsy |
| Sample Type / Matrix | Formalin-fixed paraffin-embedded (FFPE) tissue block or fresh tissue biopsy (archival solid tissue specimen) |
| Methodology Used | Quantitative Immunohistochemistry with Automated Digital Image Analysis |
| ICD-10-CM Code | C50.9 |
| LOINC Code | 69006-3 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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