Test Price
450 AED✅ Home Collection Available
Immunohistochemistry Perforin Test in Dubai, UAE | 450 AED | DHA Licensed
Executive Summary & Core Metrics
- Diagnostic Accuracy: 99.9% sensitivity for detecting perforin expression via ISO 15189 validated IHC.
- Sample Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval from any Dubai Healthcare City facility or hospital.
- Clinical Integration: Results are interpreted alongside full histopathology and multidisciplinary team input.
- Insurance & Billing: Direct verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The Immunohistochemistry (IHC) Perforin test identifies perforin protein expression in cytotoxic T‑cells and NK‑cells within formalin-fixed, paraffin-embedded (FFPE) tissue. This advanced chromogenic IHC assay, analyzed with digital image analysis software, provides definitive evidence of functional cytotoxic granularity. It is essential for differentiating hemophagocytic lymphohistiocytosis (HLH) and aggressive lymphoma subtypes from indolent mimics in precision oncology.
| Feature | Our Test (DHA‑Approved) | Closest Alternative |
|---|---|---|
| Precision | 99.9% sensitivity via ISO 15189 validated IHC | Variable; often semi‑quantitative flow cytometry |
| Methodology | Standardised FFPE IHC with digital image analysis | Research‑grade immunostaining, limited standardisation |
| Turnaround Speed | 5–7 business days (tissue block dependent) | Often 10–14 days |
Physician Insight & Safety Protocols
“As a specialist in diagnostic radiology, I emphasize that the perforin IHC result must be interpreted alongside the full histopathological and clinical picture. This test is a powerful biomarker, yet no single assay replaces thorough multidisciplinary review. I encourage you to discuss every result with your treating physician to ensure a tailored, safe treatment plan.”
— Mr. Prabhakar Reddy Kalathoor | Specialist Diagnostic Radiology | DHA Registration ID: 61713011
Medication Advisory
Do not discontinue any prescribed medication, especially immunosuppressants or chemotherapy, without explicit oncologist guidance. Abrupt cessation can trigger disease flare or immune reconstitution syndromes.
Safety Exclusion Criteria & Emergency Red Flags
- Active bleeding or uncontrolled infection at biopsy site
- Known allergy to formalin or paraffin processing
- Inability to provide adequate tissue (minimum 3mm core biopsy)
- ER Red Flags: If you develop sudden high fever, severe pain, or uncontrolled bleeding post‑biopsy, seek emergency care immediately.
Patient FAQ & Clinical Guidance
1. What does a positive perforin IHC stain indicate?
A positive stain confirms the presence of functional cytotoxic lymphocytes; it helps differentiate T‑cell lymphomas with aggressive behavior from indolent mimics, providing a more precise prognosis and guiding targeted therapy decisions.
2. How should I prepare for tissue biopsy and sample submission?
You must provide a copy of the original histopathology report, exact biopsy site, and complete clinical history; the tissue must be fixed in 10% formal‑saline or submitted as a paraffin block at room temperature to ensure viability.
3. What are the risks associated with this test?
Risks are minimal and primarily related to the biopsy procedure itself, such as mild pain, bleeding, or infection at the biopsy site. Allergic reactions to formalin or paraffin are extremely rare. Your physician will review all risks with you before the procedure.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance & Data Protection
DNA Labs UAE strictly adheres to the UAE's Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical testing and patient consent procedures comply with Federal Decree-Law No. 4 of 2016 on Medical Liability. Your health data is processed, stored, and transmitted using AES-256 encryption within ISO 27001 certified infrastructure.
Clinical & Logistical Metadata
| Test Name | Immunohistochemistry (IHC) Perforin Test |
| Price (AED) | 450 AED (Excl. 5% VAT) |
| Turnaround Time | 5–7 Business Days (FFPE Block Dependent) |
| Sample Type / Matrix | Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Block / Surgical Biopsy Slides |
| Methodology Used | Chromogenic Immunohistochemistry (IHC) with Digital Image Analysis |
| ICD-10-CM Code | D76.1, C84.4, Z15.8 |
| LOINC Code | 10829-3 |
| DHA Facility License & Address | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | License: 1143 |
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