Test Price
450 AED✅ Home Collection Available
Immunohistochemistry Neurofilament Polypeptide Test in UAE | 450 AED | DHA Licensed
Executive Summary & Core Metrics
Precision immunohistochemistry testing for neural crest tumors and neuroendocrine malignancies with accredited laboratory processing and expert clinical guidance.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Specimen Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval for FFPE blocks and archival tissue.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by DHA-licensed specialists.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The Immunohistochemistry (IHC) Neurofilament Polypeptide Test uses highly specific monoclonal antibodies to detect neurofilament protein expression in formalin-fixed, paraffin-embedded (FFPE) tissue. It is a cornerstone in the diagnostic workup of neural crest-derived malignancies, neuroendocrine tumors, and small round blue cell tumors, directly informing precision oncology decisions. Automated IHC on Benchmark platforms with DAB detection and internal positive and negative controls ensures standardized, reproducible results with digital image analysis for objective scoring.
| Feature | Our IHC Neurofilament Test | Closest Alternative (Standard IHC) |
|---|---|---|
| Precision & Sensitivity | 99.9% sensitivity; validated monoclonal antibody clones with digital image analysis | Variable sensitivity; manual scoring; risk of inter-observer variability |
| Methodology | Automated IHC on Benchmark platforms; DAB detection; internal positive/negative controls | Manual IHC; often lacks standardized external controls |
| Turnaround Time | 5 working days (block); up to 7 days for complex resections | 7–10 working days |
Physician Insight & Safety Protocols
“As a DHA-registered Specialist Diagnostic Radiology consultant, I want you to know that this IHC marker is a powerful diagnostic ally, but it must be interpreted together with the complete histopathological context and clinical presentation. A positive neurofilament result guides us toward targeted therapies, yet no single test replaces the full clinical picture. Your safety is our priority, and I encourage you to discuss every result with your treating oncologist.”
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology, DHA Registration ID: 61713011
⚠️ Important Advisory: Do Not Alter Medications Without Consultation
Do not discontinue any prescribed medication or modify your treatment plan based solely on this test result without prior discussion with your treating physician. This IHC report is one component of a comprehensive diagnostic workup and must be reviewed in conjunction with clinical history, imaging, and molecular findings.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Inadequate or non-representative tissue samples (e.g., <5% tumor cellularity, extensive necrosis); missing histopathology report or clinical history.
- Emergency Red Flags (seek immediate care): Rapidly progressive neurological deficits (severe headache, vision loss, limb weakness), signs of spinal cord compression, uncontrolled pain, or new-onset seizures. Do not wait for test results in these situations.
Patient FAQ & Clinical Guidance
1. What is the purpose of the IHC neurofilament test?
Immunohistochemistry for neurofilament distinguishes neurogenic tumors from carcinomas, guiding targeted therapy decisions with high precision. It is routinely used to classify small round blue cell tumors, confirm neuroendocrine differentiation, and support diagnoses such as neuroblastoma, medulloblastoma, and paraganglioma. The result shapes chemotherapy and surgical planning.
2. How should I prepare for the neurofilament test?
Provide the FFPE tissue block and histopathology report; no fasting, medication changes, or special preparation is needed. Simply ensure the biopsy specimen is submitted in 10% formalin-saline or as a formalin-fixed paraffin block. Include a copy of the original histopathology report and the precise biopsy site. Our logistics team arranges secure courier retrieval of the solid tissue specimen at your convenience.
3. What do my results mean?
Positive neurofilament IHC indicates neural or neuroendocrine origin, often in neuroblastoma, paraganglioma, or medullary carcinoma, impacting therapy. A positive result points toward tumors of the sympathetic nervous system, neural crest, or neuroendocrine system. A negative result suggests alternative diagnoses such as lymphoma or Ewing sarcoma. Your oncologist will combine this with imaging and molecular tests for a definitive plan.
4. Is the test covered by insurance?
Coverage depends on your specific insurance policy and the clinical indication determined by your referring physician. Our team can verify your direct billing eligibility via WhatsApp at +971 54 548 8731. We recommend contacting us prior to sample submission to confirm coverage details and any required pre-authorization.
UAE Regulatory & Data Privacy Adherence
All patient information and clinical data are handled in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent and clinical safety protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE maintains rigorous data encryption, access controls, and audit trails to safeguard your health information throughout the testing lifecycle.
Clinical & Logistical Metadata
| Test Name | Immunohistochemistry Neurofilament Polypeptide Test |
| Price (AED) | 450 |
| Turnaround Time | 5-7 Working Days |
| Sample Type / Matrix | Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Block |
| Methodology Used | Automated Immunohistochemistry (IHC) with DAB Detection |
| ICD-10-CM Code | C47.9 (Malignant neoplasm of peripheral nerves and autonomic nervous system, unspecified) |
| LOINC Code | 104432-1 (Neurofilament protein [Presence] in Tissue by Immunohistochemistry) |
| DHA Facility License & Laboratory Address | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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