Test Price
1,200 AED✅ Home Collection Available
Immunohistochemistry Microsatellite Instability (MSI) Panel in UAE | 1200 AED | 2026 DHA Guidelines
تحليل لوحة عدم استقرار السواتل الميكروية بالكيمياء المناعية النسيجية (MSI) في الإمارات | ١٢٠٠ درهم | معتمد من هيئة الصحة بدبي
Executive Summary
ضمان دقة تشخيصية بنسبة 99.9% عبر معالجة معتمدة بمعايير ISO، وجمع عينات منزلية بمستوى المستشفيات عبر خدمة الفصد المتنقلة، مع استشارة سريرية هاتفية بعد النتائج.
- ✔️ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- ✔️ Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy.
- ✔️ Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- ✔️ Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Overview
The Immunohistochemistry Microsatellite Instability (MSI) Panel is a combined immunohistochemical and molecular test that evaluates mismatch repair (MMR) protein expression (MLH1, MSH2, MSH6, PMS2) and microsatellite instability status — a critical biomarker for Lynch syndrome screening, colorectal and endometrial cancer prognosis, and immunotherapy (PD-1/PD-L1) eligibility. لوحة MSI توفر تحليلًا مناعيًا نسيجيًا وجزيئيًا لتحديد قابلية الأورام للعلاج المناعي وتقييم خطر متلازمة لينش.
| Feature | Our MSI Panel (Next‑Gen) | Standard IHC Only |
|---|---|---|
| Precision | IHC + confirmatory PCR‑STR fragment analysis | IHC staining only; risk of false‑negatives |
| Method | Monoclonal antibodies + capillary electrophoresis (Bethesda panel markers) | Immunoperoxidase DAB detection |
| Turnaround | 5–7 days (block/tissue) with digital report | 3–5 days, often without MSI confirmation |
Physician Insight & Safety Protocol
“The MSI panel result should always be interpreted alongside the patient’s clinical history, family cancer profile, and histopathology to guide Lynch syndrome surveillance, chemotherapy, or immunotherapy decisions. A positive MSI‑high result in colorectal or endometrial tumours can redefine treatment pathways and hereditary risk counselling. I encourage patients to discuss all findings with their treating oncologist or genetic counsellor.”
— Dr. PRABHAKAR REDDY, DHA License 61713011, Consultant Molecular Pathologist
⚠️ Medication Safety & Clinical Warning
Do not discontinue prescribed medication without consulting your doctor. MSI testing does not require alteration of current therapies; however, results may inform future treatment decisions that should be managed by your oncology team.
Exclusion Criteria & Red Flags
- No patient exclusions for the test itself; however, the biopsy site must be fully healed before sample submission.
- Inadequate or improperly fixed tissue (e.g., decalcified specimens) may yield indeterminate results.
- Emergency Red Flags: If you experience fever, excessive bleeding, swelling, or severe pain at the biopsy site, seek immediate medical attention.
Patient FAQ & Clinical Guidance
What is an MSI panel and why is it needed?
The MSI panel determines whether a tumour exhibits microsatellite instability, a genomic hallmark that can indicate Lynch syndrome, predict response to immunotherapy, and guide chemotherapy decisions in colorectal and endometrial cancers.
تحدد لوحة MSI عدم استقرار السواتل الميكروية في الورم مما يساعد على كشف متلازمة لينش وتوجيه العلاج المناعي.
How is the sample collected and what preparation is needed?
A tumour tissue sample (FFPE block or biopsy in formalin) is required; no fasting or medication changes are needed. Please provide a copy of the histopathology report, biopsy site details, and clinical history.
يتم جمع عينة من نسيج الورم (كتلة شمعية أو خزعة في الفورمالين) مع تقرير الأنسجة وتفاصيل الخزعة.
How long until I receive my results?
Results are ready in 5 days for FFPE blocks, 5 days for tissue biopsies, and up to 7 days for large/complex specimens, with a digital report and optional teleconsultation.
تظهر النتائج خلال 5 أيام للكتل الشمعية والخزعات، و7 أيام للعينات الكبيرة، مع تقرير رقمي واستشارة هاتفية.
Pre‑ requirements: Submit tumor tissue in 10% formal‑saline or a formalin‑fixed paraffin‑embedded (FFPE) block; ship at room temperature. Always attach a copy of the histopathology report, biopsy site, and clinical history.
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