Test Price
450 AED✅ Home Collection Available
Immunohistochemistry Cytokeratin (Pan-Cytokeratin) Test in UAE | 450 AED | 2026 DHA Guidelines
تحليل الكيمياء النسيجية المناعية للسيتوكيراتين (سيتوكيراتين شامل) في الإمارات | 450 درهم | معتمد من هيئة الصحة بدبي
الملخص التنفيذي: تحليل نسيجي مناعي دقيق للسيتوكيراتين الشامل لتشخيص الأورام الظهارية وفق بروتوكولات هيئة الصحة بدبي.
- ✓ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- ✓ Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain & VIP Mobile Phlebotomy (8 AM – 11 PM).
- ✓ Clinical Guidance: Telephonic Post-Test Result Interpretation with a DHA-Licensed Specialist.
- ✓ Insurance & Billing: Direct Billing Verification via WhatsApp: +971 54 548 8731.
Clinical Test Overview
The Immunohistochemistry Cytokeratin (Pan-Cytokeratin) Test is a gold-standard tissue‑based assay that uses a cocktail of monoclonal antibodies (AE1/AE3) to detect epithelial cytokeratin proteins, confirming carcinoma origin and guiding oncologic management. يكشف اختبار الكيمياء النسيجية المناعية الشامل للسيتوكيراتين بروتينات الخلايا الظهارية لتأكيد السرطانات الظهارية، وهو معتمد من هيئة الصحة بدبي وفق أحدث إرشادات 2026.
| Feature | Our Pan-Cytokeratin IHC Test | Standard Histopathology Alone |
|---|---|---|
| Methodology | Automated IHC with AE1/AE3 primary antibody cocktail | H&E staining, may miss subtle epithelial differentiation |
| Diagnostic Sensitivity | >99% for carcinomas of all primary sites | Variable; often requires additional IHC markers |
| Turnaround Time | 5–7 days (block/biopsy/complex) | 3–5 days for basic morphology only |
| Clinical Relevance | Essential for carcinoma diagnosis, metastatic workup, and therapy selection | Limited to morphological classification |
Physician Insight & Safety Protocol
“Every cancer journey begins with an accurate tissue diagnosis. This test, when interpreted alongside your full clinical history and imaging, provides a critical foundation for personalized treatment planning. I encourage you to discuss all results in detail with your treating oncologist—we offer complimentary telephonic guidance to clarify any questions.”
— Dr. PRABHAKAR REDDY, DHA License: 61713011, Consultant Histopathologist
⚠️ Medication Warning: Do not discontinue any prescribed medication or modify your treatment plan based on this test result without consulting your doctor.
Exclusion Criteria & Red Flags
- Inadequate Sample: Tissue with extensive necrosis, calcification, or decalcification may yield inconclusive results.
- Insufficient Tumor Cells: Biopsy containing mainly normal tissue cannot be processed for Pan-Cytokeratin IHC.
- Pregnancy & Biopsy Risks: Invasive biopsy in pregnant patients requires multidisciplinary evaluation; contact our clinical team prior to sample collection.
- Emergency Indicator: If rapid clinical deterioration or signs of metastatic crisis are present, do not wait for immunohistochemical results—seek immediate emergency oncology consultation.
Patient FAQ & Clinical Guidance
What is the Pan-Cytokeratin IHC test used for?
Snippet: The Pan-Cytokeratin Immunohistochemistry test detects cytokeratin proteins in tissue to confirm carcinoma origin and guide targeted cancer therapy.
It is routinely ordered when a tumor’s cell lineage is unclear on routine histology, helping to distinguish epithelial cancers (carcinomas) from mesenchymal tumors, lymphomas, or melanomas.
ما هو استخدام اختبار السيتوكيراتين الشامل؟
يكشف اختبار الكيمياء النسيجية المناعية للسيتوكيراتين الشامل بروتينات السيتوكيراتين في الأنسجة لتأكيد أصل السرطان الظهاري وتوجيه العلاج الموجه، وهو ضروري قبل البدء بأي علاج كيميائي أو جراحي.
How is the test performed, and what sample is required?
Snippet: The test requires a tumor tissue sample, either a biopsy fixed in formalin or a paraffin block, processed via automated IHC staining.
A small piece of the tumor is obtained during a biopsy or surgery, placed immediately in 10% formal‑saline, and sent to our ISO‑accredited lab. We also accept formalin‑fixed paraffin‑embedded (FFPE) blocks. A copy of the histopathology report, biopsy site, and clinical history must be provided to ensure accurate interpretation.
كيف يتم إجراء الاختبار وما العينة المطلوبة؟
يتطلب الاختبار عينة نسيجية من الورم، إما خزعة مثبتة في الفورمالين أو كتلة شمعية، وتُعالج بواسطة التلوين الكيميائي المناعي الآلي في مختبرنا الحاصل على شهادة الأيزو.
What do the results mean, and how quickly can I get them?
Snippet: Positive Pan-Cytokeratin staining indicates epithelial carcinoma; negative results suggest non-epithelial tumors, requiring further immunohistochemical workup.
Results are available within 5 days for standard blocks/biopsies and up to 7 days for large complex specimens. A positive result confirms epithelial differentiation and supports a diagnosis of carcinoma, while a negative result warrants additional markers (e.g., vimentin, S100) to identify sarcoma, lymphoma, or melanoma. Our specialists provide a comprehensive report with guidance on the next steps.
ماذا تعني النتائج وما مدة الحصول عليها؟
النتيجة الإيجابية لتلوين السيتوكيراتين الشامل تؤكد وجود سرطان ظهاري، أما السلبية فتشير إلى أورام غير ظهارية وتستدعي فحوصات مناعية إضافية، وتصدر التقارير خلال 5 إلى 7 أيام.
Pre‑ Requirements
- Provide a copy of the initial histopathology report (mandatory).
- Indicate the exact site of biopsy and laterality if applicable.
- Submit a detailed clinical history, including any prior chemotherapy or radiotherapy.
- Tissue must be fixed in 10% neutral-buffered formalin or submitted as an FFPE block shipped at room temperature.
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