Test Price
450 AED✅ Home Collection Available
Immunohistochemistry Cytokeratin (Pan-Cytokeratin) Test in UAE | 450 AED | DNA Labs UAE
Executive Summary & Core Metrics
- ✓ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- ✓ Premium Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval (available daily from 8 AM to 11 PM).
- ✓ Clinical Guidance: Telephonic Post-Test Result Interpretation with a DHA-Licensed Specialist.
- ✓ Insurance & Billing: Direct Billing Verification via WhatsApp: +971 54 548 8731.
Test Overview & Methodology
The Immunohistochemistry Cytokeratin (Pan-Cytokeratin) Test is a gold‑standard tissue‑based assay that uses a cocktail of monoclonal antibodies (AE1/AE3) to detect epithelial cytokeratin proteins, confirming carcinoma origin and guiding oncologic management. This test is essential when a tumor's cell lineage remains ambiguous after routine histopathological evaluation, enabling precise differentiation between epithelial cancers and mesenchymal tumors, lymphomas, or melanomas.
| Feature | Our Pan-Cytokeratin IHC Test | Standard Histopathology Alone |
|---|---|---|
| Methodology | Automated IHC with AE1/AE3 primary antibody cocktail | H&E staining, may miss subtle epithelial differentiation |
| Diagnostic Sensitivity | Greater than 99% for carcinomas of all primary sites | Variable; often requires additional IHC markers for confirmation |
| Turnaround Time | 5–7 business days (block/biopsy/complex specimens) | 3–5 days for basic morphological assessment only |
| Clinical Relevance | Essential for carcinoma diagnosis, metastatic workup, and therapy selection | Limited to morphological classification without lineage-specific confirmation |
Physician Insight & Safety Protocols
"Accurate tissue diagnosis is the cornerstone of effective cancer management. The Pan-Cytokeratin IHC test provides critical clarity in identifying epithelial carcinomas, directly influencing therapeutic strategies. I encourage patients to review their comprehensive report with their primary oncologist. Our team is available for a complimentary telephonic consultation to discuss any questions regarding the findings."
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology, DHA License: 61713011
Advisory on Treatment Continuity
Maintain All Prescribed Therapies: This test provides diagnostic information only. Do not alter or discontinue any medications, cancer treatments, or therapies without explicit guidance from your supervising physician.
Exclusion Criteria & Red Flags
- Inadequate Sample: Tissue with extensive necrosis, calcification, or decalcification may yield inconclusive results.
- Insufficient Tumor Cells: Biopsy containing mainly normal tissue cannot be processed for Pan-Cytokeratin IHC.
- Pregnancy & Biopsy Risks: Invasive biopsy in pregnant patients requires multidisciplinary evaluation; contact our clinical team prior to sample collection.
- Emergency Indicator: If rapid clinical deterioration or signs of metastatic crisis are present, do not wait for immunohistochemical results—seek immediate emergency oncology consultation.
Patient FAQ & Clinical Guidance
1. What is the Pan-Cytokeratin IHC test used for?
The Pan-Cytokeratin Immunohistochemistry test detects cytokeratin proteins in tissue to confirm carcinoma origin and guide targeted cancer therapy. It is routinely ordered when a tumor's cell lineage is unclear on routine histology, helping to distinguish epithelial cancers from mesenchymal tumors, lymphomas, or melanomas.
2. How is the test performed, and what sample is required?
The test requires a tumor tissue sample, either a formalin-fixed paraffin-embedded (FFPE) block or unstained biopsy slides. A small piece of the tumor is obtained during biopsy or surgery, fixed in 10% formalin, and sent to our ISO-accredited laboratory via a secure medical courier. A copy of the initial histopathology report, biopsy site details, and clinical history must be provided to ensure accurate interpretation.
3. What do the results mean, and how quickly can I get them?
Positive Pan-Cytokeratin staining indicates epithelial differentiation and supports a diagnosis of carcinoma. Negative results suggest non-epithelial tumors, requiring further immunohistochemical workup with markers such as vimentin or S100. Results are available within 5 business days for standard blocks and up to 7 days for large complex specimens. Your comprehensive report includes clear guidance on the next steps.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Our clinical laboratory maintains DHA Facility License 1143 and ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139). All tissue specimens are handled under protocols aligned with Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring patient safety and diagnostic integrity are never compromised.
Clinical & Logistical Metadata
| Test Name | Immunohistochemistry Cytokeratin (Pan-Cytokeratin) |
| Price (AED) | 450 |
| Turnaround Time | 5–7 business days |
| Sample Type / Matrix | Formalin-fixed paraffin-embedded (FFPE) tissue block or biopsy slides |
| Methodology Used | Automated IHC with AE1/AE3 monoclonal antibody cocktail |
| ICD-10-CM Code | C80.1, Z85.9 |
| LOINC Code | 21585-5 |
| DHA Facility License & Laboratory Address | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | License: 1143 |
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