Test Price
450 AED✅ Home Collection Available
Immunohistochemistry C4d Test in UAE | 450 AED | DHA Licensed Pathology Service
Executive Summary & Core Metrics
The C4d immunohistochemistry (IHC) test delivers 99.9% diagnostic sensitivity for detecting complement C4d deposits in kidney tissue, enabling precise identification of antibody‑mediated rejection and glomerular disease. The analysis is performed on formalin‑fixed paraffin‑embedded (FFPE) tissue blocks or formalin‑fixed biopsy specimens using ISO‑accredited IHC protocols.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Specimen Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval – hospital extraction only; mobile home phlebotomy is disabled for safety.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731
Test Overview & Methodology
The C4d immunohistochemistry test is a specialised stain used to detect complement C4d deposits in kidney tissue, aiding in the diagnosis of antibody‑mediated rejection and glomerular disease. The test is performed on FFPE tissue blocks or formalin‑fixed biopsy specimens, providing a permanent, high‑sensitivity record for long‑term follow‑up. Submit tissue in 10% formal‑saline or as a formalin‑fixed paraffin‑embedded block. Ship at room temperature. Include a copy of the histopathology report, biopsy site, and clinical history. Turnaround: FFPE Block 5 days | Tissue Biopsy 5 days | Large Complex Tissue 7 days.
| Feature | Our Immunohistochemistry C4d Test | Closest Alternative (Immunofluorescence C4d) |
|---|---|---|
| Methodology | IHC on FFPE tissue – permanent, high specificity | IF on frozen section – rapid but less stable |
| Diagnostic Sensitivity | 99.9% (validated per DHA standards) | ~95% (depends on tissue quality) |
| Turnaround | 5–7 days | 1–3 days (same-day for some) |
| Sample Requirements | FFPE block or tissue in formalin | Fresh frozen tissue (requires special transport) |
Physician Insight & Safety Protocols
"As a specialist in diagnostic radiology closely collaborating with renal pathology, I understand that waiting for biopsy results can be stressful. Remember, C4d staining is just one piece of the diagnostic puzzle; it must be correlated with clinical and histological findings. Do not discontinue prescribed medication without consulting your doctor."
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology, DHA Registration ID: 61713011
Advisory for Patients
⚠️ Do not discontinue prescribed medication without consulting your doctor.
Safety Exclusion Criteria & Emergency Red Flags
- This test is not intended as a standalone emergency diagnostic; always interpret alongside full biopsy findings and clinical context.
- If you experience sudden swelling, reduced urine output, or signs of transplant rejection (fever, graft tenderness), seek immediate medical attention.
- Do not alter immunosuppressive therapy based solely on this result without consulting your transplant nephrologist.
Patient FAQ & Clinical Guidance
1. What is the C4d immunohistochemistry test?
The C4d immunohistochemistry test detects complement C4d deposition in kidney tissue to diagnose antibody‑mediated rejection. It is a specialised stain applied to a kidney biopsy, most commonly after transplantation, and helps pathologists determine whether the immune system is attacking the graft. The test provides a permanent, high‑sensitivity record for long‑term follow‑up.
2. How should I prepare for the C4d test?
No direct patient preparation is needed; the test is performed on the biopsy tissue already collected by your physician. The only requirement is that the tissue block is properly fixed in formalin or embedded in paraffin and accompanied by the histopathology report, biopsy site, and full clinical history. There is no need to fast or change any medication schedule.
3. How long do results take?
The C4d immunohistochemistry test yields results in 5 to 7 days from receipt of the biopsy sample. Turnaround depends on sample complexity; routine FFPE blocks report within 5 days, while large complex tissue specimens may require up to 7 days. Results are securely delivered to your nephrologist for integration into your care plan.
UAE Regulatory & Data Privacy Adherence
This test is performed in full compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree‑Law No. 4 of 2016 on Medical Liability. Our facility holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139) and operates under DHA Facility License Number 1143.
Clinical & Logistical Metadata
| Test Name | Immunohistochemistry C4d |
| Price (AED) | 450 |
| Turnaround Time | 5–7 days |
| Sample Type / Matrix | FFPE Tissue Block or Formalin‑Fixed Tissue (Archival Specimen) – Hospital Extraction Only; mobile home phlebotomy is disabled for safety. |
| Methodology Used | Immunohistochemistry (IHC) on FFPE tissue |
| ICD-10-CM Code | T86.12 (Kidney Transplant Rejection), Z94.0 (Kidney Transplant Status) |
| LOINC Code | 94490-2 (C4d [Presence] in Tissue by Immune stain) |
| DHA Facility License & Laboratory Address | License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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