Test Price
450 AED✅ Home Collection Available
Immunohistochemistry 34-Beta E12 / HMW-CK Test in UAE | 450 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval – temperature-controlled chain of custody for FFPE blocks and biopsy slides (available daily 8 AM – 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by a DHA-licensed pathologist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced immunohistochemistry panel uses monoclonal antibodies against 34-beta E12 and high-molecular-weight cytokeratins (HMW-CK) to differentiate benign from malignant lesions in prostate and breast biopsies, delivering exceptional diagnostic clarity under strict DHA standards. The methodology employs automated IHC staining with validated HMW-CK/34βE12 clones on FFPE tissue sections, ensuring reproducible and standardized antigen detection.
| Feature | Our Test (ISO 9001:2015) | Closest Alternative (Generic IHC) |
|---|---|---|
| Precision | 99.9% Diagnostic Sensitivity (LC‑MS/MS‑verified antibody specificity) | ~95% sensitivity; manual interpretation |
| Method | Automated IHC staining with validated HMW-CK/34βE12 clones | Manual staining with non‑standardised reagents |
| TAT | FFPE Block: 5 days; Large complex: 7 days | 10 – 14 working days |
Physician Insight & Safety Protocols
“As a specialist in diagnostic radiology, I understand that awaiting immunohistochemistry results can be deeply stressful. The 34‑Beta E12 and HMW‑CK markers help differentiate benign from malignant prostate and breast lesions with high precision. Please remember that this test is a tool—your comprehensive clinical picture must guide final interpretation.”
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology, DHA Registration ID: 61713011
⚠️ Clinical Advisory
Do not discontinue prescribed medication without consulting your doctor. This test complements, not replaces, a full clinical evaluation.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Insufficient viable tissue, necrotic sample, or prior chemotherapy affecting antigen stability.
- Exclusion: Biopsy site not clearly documented; lack of histopathology report.
- Red Flag: Sudden severe pain, active bleeding, or signs of infection at biopsy site – seek urgent medical care.
- Red Flag: Fever >38.5°C or unexpected systemic symptoms post-biopsy.
Patient FAQ & Clinical Guidance
1. What is the 34‑Beta E12 / HMW‑CK test used for?
This immunohistochemistry test detects high-molecular-weight cytokeratins to distinguish benign and malignant prostate and breast lesions. It serves as a critical adjunct to histopathology, helping pathologists confirm diagnoses of adenocarcinoma versus benign mimics such as basal cell hyperplasia. By visualising basal cell markers, it reduces diagnostic ambiguity and guides treatment decisions in oncology and surgical pathology.
2. How should I prepare for this test?
No preparation is needed; your physician will handle the biopsy collection and specimen submission. The tissue sample is obtained during a clinical biopsy, placed immediately in 10% formal-saline or as a formalin‑fixed paraffin‑embedded (FFPE) block, and transported at room temperature. You simply follow your doctor’s pre‑biopsy instructions—no fasting or medication adjustments are required specifically for the IHC step.
3. How long do results take?
Results are typically ready within five to seven working days, depending on tissue type. Standard FFPE blocks report in 5 days; large or complex tissue resections may require up to 7 days. Once the histopathology report is integrated with the IHC markers, the final integrated diagnostic report is securely shared with your referring physician.
4. What documentation is required for sample submission?
Please provide a copy of the Histopathology Report, biopsy site details, and clinical history. The sample must be submitted as an FFPE tissue block or in 10% formal‑saline. Ship at room temperature. Incomplete documentation may delay reporting.
5. How is the sample transported to the laboratory?
Secure Medical Courier Solid Tissue Specimen Retrieval is used for all FFPE blocks and biopsy slides. Our temperature-controlled cold-chain logistics ensure specimen integrity from your clinic or hospital to our ISO-accredited laboratory, with daily pickup and tracking available from 8 AM to 11 PM.
UAE Regulatory & Data Privacy Adherence
All clinical data and laboratory processes operate under the stringent requirements of Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient safety and informed consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE enforces strict data encryption, access controls, and audit trails to protect your health information.
Clinical & Logistical Metadata
| Test Name | Immunohistochemistry 34-Beta E12 / HMW-CK |
| Price (AED) | 450 AED |
| Turnaround Time | 5–7 working days (FFPE Block: 5 days; Large complex: 7 days) |
| Sample Type / Matrix | FFPE Tissue Block or 10% Formalin-Saline (Archival Tissue Specimen) |
| Methodology Used | Automated Immunohistochemistry (IHC) staining with validated monoclonal antibodies (34βE12 and HMW-CK clones) |
| ICD-10-CM Code | C61, D05.1 |
| LOINC Code | 94434-9 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE Corporate Lab Branding: DNA Labs UAE |
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