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450 AED✅ Home Collection Available
HMB-45 Immunohistochemistry (IHC) Test in UAE | 450 AED | 2026 DHA Guidelines
تحليل HMB-45 بالكيمياء المناعية في الإمارات | 450 درهم | معتمد من هيئة الصحة بدبي
ملخص تنفيذي: يكتشف هذا الفحص النسيجي المتطور مستضد HMB-45 بدقة تشخيصية 99.9% عبر معالجة ISO 9001:2015 المعتمدة. نقدّم خدمة جمع العينات المنزلية الفاخرة على مدار الساعة، وإرشاد طبي هاتفي بعد النتيجة، والتحقق الفوري من التغطية التأمينية عبر واتساب.
Executive Summary: 99.9% diagnostic accuracy – ISO-certified home collection – post-test clinical guidance – instant insurance check via WhatsApp +971 54 548 8731.
Test Overview
The HMB-45 IHC test identifies the melanosome-specific glycoprotein in tissue biopsies, providing definitive evidence for malignant melanoma and distinguishing melanocytic lesions from non-melanocytic tumors. This targeted immunostain is essential for oncologists and surgical pathologists to tailor precision oncology strategies and prognostic assessments.
| Parameter | Our HMB-45 IHC Test | Closest Alternative (S-100 IHC) |
|---|---|---|
| Diagnostic Precision | High specificity for melanosomes (melanoma marker) | Excellent sensitivity but lower specificity; stains many neural/connective tissue tumors |
| Methodology | Monoclonal HMB-45 antibody IHC on FFPE tissue | Polyclonal S-100 antibody IHC |
| Turnaround Time | 5–7 days (based on block/size) | 3–5 days typical |
| Clinical Utility | Confirms melanocytic origin; crucial for melanoma-targeted therapy eligibility | Screening marker; must be paired with melanocyte-specific stains |
Regulatory & Accreditation Compliance
Operated under Federal Decree-Law No. 41 of 2024 (Art. 87), UAE PDPL data protection, and ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139). All pathology processing follows DHA/MOHAP standards. Minors require legal guardian consent per UAE CDS Law 2026.
Physician Insight & Safety Protocol
"HMB-45 immunostaining is a powerful tool for confirming melanocytic differentiation, but it must be integrated with full histomorphology and clinical context. A positive result requires correlation with tumor architecture and may be seen in some non-melanocytic lesions; negative staining does not exclude melanoma, and a panel including Melan-A or MITF is often needed for diagnostic confidence."
– Dr. PRABHAKAR REDDY, Consultant Pathologist, DHA License: 61713011
Medication Warning: Do not discontinue any prescribed medication without consulting your doctor. Biopsy and test results must be interpreted by a qualified oncologist or pathologist.
Patient Safety & Exclusion Criteria
- Exclusion: Active infection at biopsy site, severe coagulopathy (INR >2.0, platelets <50,000/µL), inability to provide informed consent (minors require guardian consent per UAE CDS Law 2026).
- Biopsy ER Red Flags: Post-procedure fever >38°C, excessive bleeding, pus discharge, or progressive swelling at site – seek immediate medical attention.
- Sample Integrity: Tissue must be fixed in 10% formal-saline or provided as FFPE block; inadequate fixation may compromise staining accuracy.
- Clinical History: A copy of the histopathology report, biopsy site, and full clinical history are mandatory; failure to provide may delay results or lead to incomplete interpretation.
Patient FAQ & Clinical Guidance
Q: What is the HMB-45 IHC test and why is it done?
A: The HMB-45 IHC test identifies melanosome antigen in biopsy tissue to confirm melanoma, differentiate from other cancers, and guide therapy. اختبار HMB-45 بالكيمياء المناعية يكشف المستضد الميلانيني لتأكيد تشخيص الميلانوما وتمييزها عن الأورام الأخرى، مما يساعد في توجيه العلاج الدقيق.
Q: How should I prepare for the biopsy needed for this test?
A: No special preparation is required, but inform your doctor if you take blood thinners or have a bleeding disorder to avoid complications. لا حاجة لتحضيرات خاصة، لكن يجب إخبار الطبيب إذا كنت تستخدم مميعات الدم أو تعاني من اضطرابات نزف لتجنب المضاعفات.
Q: When will I receive my results and what do they mean?
A: Results are typically available within 5–7 working days; a positive HMB-45 stain supports melanocytic origin and melanoma diagnosis when correlated with histopathology. تظهر النتائج عادة خلال 5–7 أيام عمل؛ والنتيجة الإيجابية تدعم تشخيص الميلانوما عند ربطها بالفحص النسيجي والسريري.
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