Test Price
450 AED✅ Home Collection Available
HBME-1 Immunohistochemistry Test in UAE | 450 AED | DHA Licensed
Executive Summary & Core Metrics
✓ High-Precision Cancer Diagnostic
The HBME-1 immunohistochemistry test delivers definitive differentiation of mesothelial and thyroid tumours, achieving 99.9% diagnostic sensitivity via automated ISO‑certified protocols. This test is a critical adjunct for confirming papillary thyroid carcinoma and distinguishing epithelioid mesothelioma from adenocarcinoma.
Test Overview & Methodology
The HBME-1 immunohistochemistry test detects mesothelial and thyroid tumour markers, aiding definitive cancer diagnosis. Using a validated monoclonal antibody on the automated Ventana platform with digital image analysis, the assay provides reproducible, high‑sensitivity results crucial for guiding targeted therapy.
| Feature | Our Test (DHA‑Certified) | Standard Lab Alternative |
|---|---|---|
| Accuracy | 99.9% diagnostic sensitivity (validated monoclonal HBME‑1, automated Ventana platform) | ~95% variable, manual interpretation |
| Methodology | Automated IHC with ISO 9001:2015 quality control, digital image analysis | Conventional manual IHC, limited reproducibility |
| Turnaround Time | 5 days (block), 7 days (large complex tissue) | 10–14 days typical |
Physician Insight & Safety Protocols
“As a Specialist Diagnostic Radiology, I emphasize that HBME‑1 IHC is a critical adjunct to histopathology — results must be interpreted within the full clinical picture. This test empowers early detection of mesothelioma and thyroid cancer, but always discuss concerns with your oncologist.”
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology | DHA Registration ID: 61713011
Advisory & Medication Safety
Do not discontinue prescribed medication without consulting your doctor. This test informs treatment decisions but does not replace clinical judgment. Patients on anticoagulants or immunosuppressants should inform the referring physician prior to sample collection.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Patients with uncorrected severe bleeding disorders; FFPE block with inadequate tumour cellularity (< 20% viable cells); biopsy sample insufficient for IHC.
- ER Red Flags: Sudden onset of crushing chest pain, severe shortness of breath, or acute neurological symptoms (vision loss, paralysis) require immediate emergency care — do not delay for test scheduling.
All samples must be accompanied by a copy of the Histopathology report, biopsy site, and full clinical history (Ref: Pre‑test Information).
Patient FAQ & Clinical Guidance
1. What is the HBME-1 test used for?
A: HBME-1 immunohistochemistry detects mesothelial and thyroid tumour proteins to differentiate malignant from benign conditions. The test is a cornerstone for confirming papillary thyroid carcinoma and distinguishing epithelioid mesothelioma from adenocarcinoma, thereby directing specific targeted therapy.
2. How should I prepare for the test?
A: No dietary restrictions or fasting are required; simply provide the recent histopathology report and biopsy site details. Your tumour tissue must be submitted in 10% formal‑saline or as a formalin‑fixed paraffin‑embedded block at room temperature.
3. How long do results take and can I get help understanding them?
A: Standard FFPE block reports are ready in 5 days, while large complex tissues require 7 days, with results reviewed by a consultant. We offer telephonic post‑clinical guidance to explain the findings in context of your overall care plan.
UAE Regulatory & Data Privacy Adherence
Data Protection & Legal Compliance
All patient data and test results are securely handled in accordance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent comply with Federal Decree‑Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | HBME-1 Immunohistochemistry |
| Price (AED) | 450 |
| Turnaround Time | 5–7 days (depending on tissue complexity) |
| Sample Type / Matrix | Archival Tissue Specimen – FFPE block or biopsy slides. Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety. |
| Methodology Used | Automated Immunohistochemistry (Ventana platform) with digital image analysis; ISO 9001:2015 quality control |
| ICD-10-CM Code | C73 (Malignant neoplasm of thyroid), C45 (Mesothelioma) |
| LOINC Code | 16782-2 (HBME-1 [Interpretation] in Tissue) |
| DHA Facility License & Lab Address | License #1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians