Test Price
450 AED✅ Home Collection Available
CD21 Immunohistochemistry Test in the UAE – 450 AED – DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: ISO‑Certified Room‑Temperature Transport for FFPE Blocks & Formalin‑Fixed Tissue; Secure Medical Courier Solid Tissue Specimen Retrieval.
- Clinical Guidance: Telephonic Post‑Test Clinical Interpretation by DHA‑Licensed Pathologists.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The CD21 Immunohistochemistry Test precisely identifies CD21 (complement receptor 2) expression on follicular dendritic cells and B‑cell lymphomas in formalin‑fixed paraffin‑embedded (FFPE) tissue. This test is essential for classifying lymphoid neoplasms and distinguishing between reactive and neoplastic follicular patterns.
| Feature | Our CD21 IHC Test | Closest Alternative (Flow Cytometry CD21) |
|---|---|---|
| Precision | Morphological context, 1‑cell resolution on FFPE | Single‑cell suspension; may lose architecture |
| Method | Immunohistochemistry (IHC) – DAB chromogen, automated | Multiparametric flow cytometry (fresh tissue) |
| Turnaround Time | 5–7 days (block / large complex) | 2–3 days (requires viable cells) |
Physician Insight & Safety Protocols
“CD21 IHC is a critical tool for delineating follicular dendritic cell meshworks in lymphomas and reactive conditions. The result must always be interpreted alongside the H&E morphology and clinical context; a positive CD21 pattern alone does not constitute a diagnosis. I strongly advise clinicians to correlate these findings with the full immunophenotypic panel and patient history.”
— Mr. Prabhakar Reddy Kalathoor | Specialist Diagnostic Radiology | DHA Registration ID: 61713011
Medication Advisory
⚠️ Medication Warning: Do not discontinue any prescribed medication, including corticosteroids or immunosuppressants, without direct consultation with your treating physician. An IHC result is complementary, not directive.
Clinical Exclusion Criteria & Emergency Red Flags
- Tissue specimen fixed in alternative fixatives (e.g., Bouin’s, alcohol) may yield false‑negative CD21 staining — resubmission with 10% neutral buffered formalin required.
- Insufficient tumour content (<5%) on the block; a repeat biopsy or deeper sections may be necessary.
- Patients experiencing acute anaphylaxis, uncontrolled bleeding at biopsy site, or sudden dyspnea must seek emergency care immediately; do not wait for immunohistochemistry results.
- Minors require guardian consent in compliance with Federal Decree‑Law No. 4 of 2016 on Medical Liability; no direct‑to‑consumer IHC without physician referral.
Patient FAQ & Clinical Guidance
1. What does the CD21 immunohistochemistry test detect, and why is it ordered?
CD21 immunohistochemistry staining detects follicular dendritic cells and helps diagnose mantle cell lymphoma and other B-cell neoplasms in tissue biopsies. This test is typically requested by oncologists and surgical pathologists when a lymphoma or an unusual reactive condition is suspected on histopathology. The presence and pattern of CD21+ follicular dendritic cell networks can distinguish between types of B‑cell lymphomas and reactive hyperplasia, guiding targeted therapy decisions.
2. How should I prepare and submit my sample for the CD21 IHC test?
Submit the formalin‑fixed, paraffin‑embedded tissue block or a container with tumor tissue in 10% neutral buffered formalin at room temperature, along with the original histopathology report and clinical history. No fasting or medication changes are required for this tissue‑based test. Our logistics team can arrange a dedicated courier for block retrieval from your hospital or pathology lab, ensuring chain‑of‑custody and ISO‑compliant handling. Include the site of biopsy and a brief clinical note for accurate interpretation.
3. What is the turnaround time and how will I receive my CD21 result?
The report is available within 5 days for FFPE blocks, 5 days for tissue biopsies, and 7 days for large complex specimens after daily receipt by 6 pm. Results are delivered via a secure, DHA‑compliant digital portal, and you also receive a telephonic consultation with a pathologist who explains the clinical significance. All data is protected under UAE PDPL and Federal Law No. 2 of 2019, ensuring absolute confidentiality.
UAE Regulatory & Data Privacy Adherence
UAE Regulatory Compliance: Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
Facility License: DHA Facility License No. 1143 | ISO 9001:2015 Certificate INT/EGQ/2509DA/3139
Patient Support: +971 54 548 8731 (8 AM – 11 PM, WhatsApp & Courier Coordination)
Clinical & Logistical Metadata
| Test Name | CD21 Immunohistochemistry |
| Price (AED) | 450 |
| Turnaround Time | 5–7 Business Days |
| Sample Type / Matrix | Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Block |
| Methodology Used | Automated Immunohistochemistry (IHC) with DAB Chromogen |
| ICD-10-CM Code | C83.30 |
| LOINC Code | 49469-8 |
| DHA Facility License & Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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