Test Price
450 AED✅ Home Collection Available
CD20 Immunohistochemistry (IHC) Test – DHA Licensed | 450 AED | DNA Labs UAE
Executive Summary & Core Metrics
Executive Summary
- Test: CD20 Immunohistochemistry (IHC) – 450 AED
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing
- Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval – archival paraffin blocks or fresh tissue biopsy. Home phlebotomy is not applicable for tissue specimens.
- Clinical Guidance: Telephonic Post-Test Guidance for result interpretation
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731
- Facility: DHA License 1143 – DNA Labs UAE, Dubai Healthcare City
Test Overview & Methodology
The CD20 IHC test identifies the CD20 surface antigen on B‑lymphocytes within tumour tissue using a monoclonal antibody and DAB chromogen detection. This enables precise classification of B‑cell non‑Hodgkin lymphomas and guides targeted therapy with monoclonal antibodies (e.g., Rituximab). The test preserves tissue architecture, allowing direct correlation with histology.
| Feature | Our CD20 IHC Test | Flow Cytometry (Alternative) |
|---|---|---|
| Target | CD20 protein in tissue architecture | CD20 on dissociated cells |
| Method | Monoclonal antibody + DAB chromogen (IHC) | Laser‑based fluorescence |
| Turnaround Time | 5 – 7 days (block/biopsy) | 24 – 48 hours |
| Morphological Context | Preserved – correlates directly with histology | Lost – cells in suspension |
| Regulatory Compliance | DHA‑approved, ISO 9001:2015, UAE PDPL | Variable |
Physician Insight & Safety Protocols
“CD20 IHC provides critical lineage information for B-cell lymphomas, but it must always be interpreted alongside histomorphology, CD3, Ki-67, and clinical findings. Treatment decisions, especially with monoclonal antibodies, require a complete lymphoma immunophenotyping panel and multidisciplinary input.”
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology, DHA Registration ID: 61713011
⚠️ Important Medication Advisory
Do not discontinue prescribed anticoagulants, immunosuppressants, or oncologic therapy without consulting your doctor.
Altering medication based solely on IHC findings may lead to thromboembolic events, disease flare, or treatment resistance.
Patient Safety: Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Active bleeding disorder, platelet count < 50×10⁹/L, anticoagulation that cannot be safely interrupted, severe local infection at biopsy site.
- Emergency Red Flags (seek immediate care): Rapidly enlarging mass, unexplained fever >38°C, drenching night sweats, unintentional weight loss >10% in 6 months, new neurological deficits suggesting spinal cord compression.
- Post‑biopsy warning: Persistent bleeding, purulent discharge, or worsening pain at the biopsy site requires urgent medical review.
Patient FAQ & Clinical Guidance
1. What does a positive CD20 IHC result mean for lymphoma diagnosis?
A positive CD20 IHC result confirms that the tumour cells are of B‑cell origin, essential for diagnosing most B‑cell lymphomas including diffuse large B‑cell lymphoma and follicular lymphoma. This finding must be interpreted alongside histology, CD3 (T‑cell marker), and proliferation index (Ki‑67) to accurately subclassify the lymphoma and guide targeted therapy.
2. How should I prepare for the CD20 IHC test – is it a blood draw or biopsy?
CD20 IHC requires a tissue sample, not a blood draw. A biopsy (needle or excision) is taken and fixed in formalin to preserve cell architecture. Our logistics team coordinates with your referring physician to obtain archival paraffin blocks or arranges a fresh tissue biopsy at a DHA‑licensed facility. Please provide a copy of the histopathology report, biopsy site, and clinical history.
3. Are there any dietary or medication restrictions before the test?
No specific dietary restrictions are required before a CD20 IHC biopsy. However, certain medications like anticoagulants or antiplatelet agents must be reviewed for safety. Always inform your doctor about all prescription, over‑the‑counter, and herbal supplements. Never stop any medication without medical clearance, especially blood thinners or immunosuppressants.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance Framework
All procedures and data handling comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety, patient consent, and medical liability adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
Our laboratory is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139) and operates under DHA License 1143. Patient data is encrypted and processed in accordance with UAE privacy regulations.
Clinical & Logistical Metadata
| Test Name | CD20 Immunohistochemistry (IHC) |
| Price (AED) | 450 |
| Turnaround Time | 5–7 Business Days |
| Sample Type / Matrix | Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Block or Biopsy Slide |
| Methodology Used | Immunohistochemistry (IHC) – Monoclonal Antibody with DAB Chromogen Detection |
| ICD-10-CM Code | C85.90 |
| LOINC Code | 74627-7 |
| DHA Facility License & Laboratory Address | DHA License 1143 – DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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