Test Price
450 AED✅ Home Collection Available
Anti-PLA2R (Phospholipase A2 Receptor) Immunohistochemistry Test in UAE | 450 AED | DHA Licensed
Executive Summary & Core Metrics
The Anti-PLA2R Immunohistochemistry (IHC) test is the gold-standard tissue biomarker for diagnosing primary membranous nephropathy (pMN) with 99.9% diagnostic sensitivity. Performed under ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139), this test detects phospholipase A2 receptor deposits in kidney biopsy tissue. Secure Medical Courier Solid Tissue Specimen Retrieval is available for previously collected FFPE blocks or slides. Post-test teleconsultation with a specialist physician for result interpretation is included. Direct insurance verification is available via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The Anti-PLA2R IHC test is performed on formalin-fixed paraffin-embedded (FFPE) kidney tissue sections using a validated immunohistochemistry protocol. It provides definitive localization of PLA2R antigen within glomerular deposits, distinguishing primary membranous nephropathy from secondary causes. The result is interpreted by a board-certified pathologist in correlation with the full histopathology report and clinical history.
| Feature | Anti-PLA2R IHC Test (Tissue) | Serum Anti-PLA2R ELISA (Alternative) |
|---|---|---|
| Clinical Precision | Tissue‑localized antibody detection – definitive for primary MN | Circulating antibody – may miss tissue‑restricted disease |
| ISO-Certified Method | Immunohistochemistry (IHC) – ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) | ELISA – not routinely ISO‑accredited for tissue correlation |
| Report Turnaround | 5–7 days from block receipt | Typically 3–5 days, but lacks tissue context |
Physician Insight & Safety Protocols
“As a specialist in diagnostic radiology with focus on renal pathology, I consider the PLA2R IHC test on kidney tissue the cornerstone for confirming primary membranous nephropathy. Results must always be correlated with the full histopathology report and clinical context. This test should never replace a thorough nephrological evaluation.”
— Mr. Prabhakar Reddy Kalathoor, DHA License 61713011
Medication Advisory
⚠️ Medication Warning
Do not discontinue prescribed medication, including immunosuppressive therapy, without consulting your doctor. This test does not replace treatment decisions made by your nephrologist. Always report any new symptoms to your healthcare provider.
Safety Exclusion Criteria & Emergency Red Flags
Important Safety Information
- Sample Submission Only: This test is performed exclusively on previously collected FFPE tissue blocks or slides. No new invasive biopsy procedure is conducted by our service.
- If a new renal biopsy is required at a DHA‑licensed facility, patients with uncorrected coagulopathy or active anticoagulant therapy must inform the nephrologist prior to the procedure.
- Emergency Red Flags: Sudden severe flank pain, gross hematuria, or inability to pass urine after any biopsy warrants immediate emergency care.
- Patients under 18 years require parental or guardian consent for sample submission. All procedures comply with Federal Decree-Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What is the Anti-PLA2R IHC test, and why is it ordered?
Anti-PLA2R IHC testing detects phospholipase A2 receptor deposits in kidney tissue to diagnose primary membranous nephropathy. This test is ordered when a renal biopsy shows features of membranous nephropathy and the clinician needs to determine whether the disease is primary (autoimmune) or secondary to other conditions such as malignancy or infection. The result directly influences treatment decisions including the use of immunosuppressive therapy.
2. How should I provide the tissue sample for this test?
Submit an FFPE tissue block or unstained slides along with the histopathology report and clinical history. The sample must be packed securely at room temperature. Our secure medical courier service can arrange pickup from your location (available daily 8 AM – 11 PM). No special patient preparation is required. A copy of the biopsy report and anatomical site details are essential for accurate interpretation.
3. What do positive PLA2R results mean for my kidney health?
A positive PLA2R result indicates primary membranous nephropathy, which may require immunosuppressive therapy guided by your nephrologist. It confirms the autoimmune nature of the disease, often sparing patients from extensive work‑up for secondary causes. Long‑term monitoring of kidney function and proteinuria remains essential even after treatment.
UAE Regulatory & Data Privacy Adherence
Your health data is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical information is processed confidentially, stored securely, and never shared without your explicit consent. This test is performed at a DHA-licensed laboratory under strict quality standards. For any data privacy concerns, contact our Data Protection Officer at privacy@dnalabs.ae.
Clinical & Logistical Metadata
| Test Name | Anti-PLA2R (Phospholipase A2 Receptor) Immunohistochemistry Test |
| Price (AED) | 450 |
| Turnaround Time | 5–7 days from receipt of tissue block/slides |
| Sample Type / Matrix | FFPE tissue block, unstained slides, or formalin-fixed tissue |
| Methodology Used | Immunohistochemistry (IHC) – ISO 9001:2015 certified |
| ICD-10-CM Code | N04.2 (Nephrotic syndrome with diffuse membranous glomerulonephritis) |
| LOINC Code | 96367-5 (Phospholipase A2 receptor antibody [Interpretation] in Tissue) |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians