Test Price
2,800 AED✅ Home Collection Available
FASLG Gene Autoimmune Lymphoproliferative Syndrome Type 1B (ALPS) Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
● Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
● Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (daily 8 AM–11 PM).
● Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by DHA-licensed physician.
● Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The FASLG gene test detects mutations in the FAS ligand gene responsible for Autoimmune Lymphoproliferative Syndrome Type 1B (ALPS-FASLG). This NGS-based assay sequences the entire coding region to identify pathogenic variants causing immune dysregulation and lymphoproliferation.
| Feature | Our Test (ALPS-FASLG NGS) | Closest Alternative (Sanger Sequencing / Panel) |
|---|---|---|
| Precision | 99.9% diagnostic sensitivity for single nucleotide variants, indels, CNVs | 90–95% for targeted mutations only |
| Method | Next-Generation Sequencing (NGS) with full gene coverage & confirmatory Sanger | Sanger sequencing of selected exons; limited CNV detection |
| Turnaround | 3–4 weeks | 4–6 weeks; panel tests often longer |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403: "The FASLG mutation analysis is a critical diagnostic step for ALPS type 1B. However, a positive result must be interpreted alongside clinical presentation and family pedigree. Genetic counseling before and after testing is essential to guide surveillance and management. Never rely on molecular results alone for therapeutic decisions."
Safety Advisory
⚠ Medication Warning
Do not discontinue or alter any prescribed immunosuppressants, corticosteroids, or other medications based solely on genetic test results. Abrupt changes may trigger disease exacerbation. Always consult with your treating physician before adjusting therapy.
Safety Exclusion Criteria & Emergency Red Flags
- Active severe infection or febrile illness – reschedule collection until fully recovered.
- Known hypersensitivity to antiseptics used in venipuncture.
- Inability to provide informed consent (for minors, parent or legal guardian must consent under UAE law).
- ER Red Flags: Sudden high fever, rapidly enlarging lymph nodes causing breathing difficulty, or signs of cytopenic crisis (extreme pallor, bruising, bleeding). Seek immediate medical attention; these indicate disease progression, not collection complication.
Patient FAQ & Clinical Guidance
1. What does a positive FASLG gene test mean for me or my child?
A positive result confirms a diagnosis of Autoimmune Lymphoproliferative Syndrome Type 1B, indicating a pathogenic mutation in the FASLG gene. This increases risk for autoimmune cytopenias, lymphadenopathy, and lymphoma. The result must be correlated with clinical and family history.
2. Is fasting or special preparation required before sample collection?
No fasting is needed. A simple blood draw, buccal swab, or dried blood spot can be collected at your convenience after mandatory pre-test genetic counseling. Our mobile phlebotomy service is available daily 8 AM–11 PM.
3. How long do results take and will a doctor explain them?
Results are delivered within 3–4 weeks. A DHA-licensed genetic counselor provides telephonic post-test guidance to interpret findings and recommend next steps. A full written report is also issued.
UAE Regulatory & Data Privacy Adherence
Compliance Framework
This test is conducted in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability. The laboratory holds DHA facility license 1143 and is ISO 9001:2015 certified.
Clinical & Logistical Metadata
| Test Name | FASLG Gene Autoimmune Lymphoproliferative Syndrome Type 1B (ALPS) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral whole blood, buccal swab, or dried blood spot; VIP mobile phlebotomy available for standard blood draws. |
| Methodology Used | Next-Generation Sequencing (NGS) of entire coding region with confirmatory Sanger sequencing. |
| ICD-10-CM Code | D89.82 |
| LOINC Code | 55233-1 |
| DHA Facility License & Laboratory Address | DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians