STS Gene (X-Linked Ichthyosis) Genetic Test in UAE | 2800 AED | DHA Licensed

Executive Summary & Core Metrics

Clinical Precision & Service Excellence

Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Next Generation Sequencing.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Home Collection (8 AM – 11 PM, daily).
Clinical Guidance: Post-test telephonic counseling by a Consultant Medical Geneticist.
Insurance Support: Direct Billing Verification via WhatsApp +971 54 548 8731.

Call Now: +971 54 548 8731 WhatsApp Inquiry

Test Overview & Methodology

The STS gene (Steroid Sulfatase) NGS test identifies pathogenic variants causing X-linked ichthyosis, a hereditary skin disorder characterized by dry, scaly skin. This advanced genetic test enables precise diagnosis, family risk assessment, and personalized management for patients in the UAE. The test uses Next Generation Sequencing (NGS) to analyze the entire coding region and splice sites of the STS gene, achieving greater than 99.9% sensitivity and specificity.

Feature	Our Test (NGS)	Alternative (Enzyme Assay)
Precision	>99.9% sensitivity & specificity	~80-90%, may miss deletions
Method	Next Generation Sequencing (full gene coverage)	Biochemical steroid sulfatase activity
Speed	3–4 weeks	2–3 weeks (less informative)
Clinical Relevance	Identifies specific mutation, carrier status, familial risk	Confirms enzyme deficiency only

Physician Insight & Safety Protocols

“As a Consultant Medical Geneticist in the UAE, I emphasize that this genetic test provides critical insights into X-linked ichthyosis but must always be interpreted alongside clinical findings and family history. Early diagnosis can guide effective skincare regimens and reduce psychological burden. Please continue all prescribed treatments and consult your doctor before any changes.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Important Advisory for Patients

Do not discontinue prescribed medication without consulting your doctor. This genetic test does not replace ongoing dermatological care. All sample collection and genetic testing procedures adhere to the safety and consent requirements of Federal Decree-Law No. 4 of 2016 on Medical Liability. Pre-test genetic counseling is strongly recommended.

Contraindications & Exclusion Criteria

Do NOT proceed without physician approval if:

Minor without formal parental consent and pre-test genetic counseling.
Active skin infection or cellulitis at intended venipuncture site.
Severe coagulopathy (e.g., hemophilia, warfarin therapy) without clearance.
Refusal to undergo pre-test genetic counseling and pedigree charting.

Seek immediate medical attention if:

Sudden blistering, ulceration, or severe pain after sample collection.
Signs of systemic allergic reaction (rash, difficulty breathing, swelling).
Fever >38.5°C or uncontrolled bleeding from puncture site.

Patient FAQ & Clinical Guidance

1. What is the purpose of this test?

Quick Answer: The STS X-linked ichthyosis Genetic Test identifies steroid sulfatase gene mutations, confirming diagnosis and guiding family planning.

This test detects deletions or pathogenic variants in the STS gene responsible for X-linked ichthyosis. It helps differentiate it from other forms of ichthyosis, assess carrier status in females, and inform genetic counseling for relatives. In the UAE, early genetic diagnosis allows personalized dermatologic management and psychosocial support.

2. How is the test performed?

Quick Answer: A blood sample is collected via a painless venipuncture by a certified phlebotomist in your home or office.

Our certified phlebotomist visits your home or office (8 AM – 11 PM) in a temperature-controlled vehicle. A small amount of blood is drawn, or an FTA card can be used for a finger-prick drop. The sample is transported in a validated cold chain to our ISO 9001:2015 lab for NGS analysis. Results are available in 3–4 weeks with optional telephonic genetic counseling.

3. What do the results mean?

Quick Answer: A positive result confirms X-linked ichthyosis, while a negative result may require further dermatology evaluation.

A positive finding indicates a disease-causing mutation in STS, confirming the diagnosis and allowing inheritance counseling. A negative result might suggest other ichthyosis types or non-genetic causes. All reports are interpreted by a board-certified geneticist and genetic counselor. You will receive a comprehensive, DHA-compliant report in English.

UAE Regulatory & Data Privacy Adherence

Data Protection: All patient data is handled in compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent is mandatory before any personal or genomic data processing.
Clinical Safety: Sample collection and testing follow the provisions of Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring patient safety and informed consent.
ISO 9001:2015 Certification: Certificate No. INT/EGQ/2509DA/3139 – Quality Management System for Genetic Diagnostics.
DHA Facility License: 1143 — Accredited by Dubai Health Authority, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.

Clinical & Logistical Metadata

Test Name	STS Gene (X-Linked Ichthyosis) NGS Genetic Test
Price (AED)	2,800 AED
Turnaround Time	3–4 weeks (21–28 business days)
Sample Type / Matrix	Peripheral Whole Blood – VIP Mobile Phlebotomy & Temperature-Controlled Home Collection
Methodology Used	Next Generation Sequencing (NGS) – Full Gene Coverage
ICD-10-CM Code	Q80.1 (X-linked ichthyosis)
LOINC Code	94222-4 (STS gene mutation analysis)
DHA Facility License & Address	DHA License No: 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE