Test Price
2,800 AED✅ Home Collection Available
ADD2 Gene Hypertension Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
This high‑precision genetic test uses next‑generation sequencing (NGS) to detect ADD2 gene variants associated with essential hypertension. It is paired with mandatory pre‑ and post‑test genetic counselling and follows DHA regulatory standards.
Test Overview & Methodology
What this test does: This advanced NGS assay examines the entire coding region of the ADD2 (adducin beta) gene, identifying germline variants strongly associated with primary (essential) hypertension susceptibility, salt‑sensitive blood pressure phenotypes, and early cardiovascular risk stratification.
Who prescribes it? General physicians, primary care doctors, and medical researchers. The test is designed for individuals with a family history of hypertension or those seeking proactive genomic wellness insights under professional supervision.
| Parameter | Our ADD2 NGS Test | Standard Single‑Gene Sequencing |
|---|---|---|
| Methodology | NGS covering all exons ± splice sites, validated by LC‑MS/MS for variant confirmation | Sanger sequencing of selected exons only |
| Variant Detection | SNVs, indels, and copy number variants (CNVs) for comprehensive risk profiling | Limited to known hot‑spot mutations |
| Turnaround Time | 3–4 weeks | 6–8 weeks |
| Clinical Utility | Precision medicine guidance, family screening, personalised antihypertensive choice | Basic diagnostic confirmation only |
Physician Insight & Safety Protocols
"The ADD2 gene plays a critical role in sodium transport and vascular tone. This NGS test gives us a powerful tool to personalise hypertension management. Remember, a genetic risk variant is not a diagnosis; it is an opportunity for early intervention. Always combine this result with your blood pressure trends, family history, and lifestyle factors for a complete picture."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA License: 9294403
Medication Advisory
⚠ Medication Warning
Do not discontinue any prescribed antihypertensive medication without consulting your physician. This test is for risk assessment, not acute management.
Exclusion Criteria & Emergency Red Flags
- Patients unwilling or unable to provide informed consent after genetic counselling.
- Minors without legal guardian consent, in compliance with UAE Federal Decree‑Law No. 4 of 2016 on Medical Liability.
- Individuals with acute hypertensive emergency (systolic >180 mmHg or diastolic >120 mmHg with organ damage) – seek immediate ER care; this test is not for crisis diagnosis.
- Severe headache, blurred vision, chest pain, shortness of breath, or confusion: proceed to nearest emergency department; genetic testing cannot replace urgent intervention.
- Pregnancy is not an exclusion but requires specialised obstetric counselling per UAE data protection rules before testing.
Patient FAQ & Clinical Guidance
1. What does the ADD2 hypertension genetic test evaluate?
Direct Answer: The ADD2 NGS test identifies DNA variants in the adducin beta gene that increase your lifelong risk of developing essential hypertension. It analyses the full coding sequence for mutations that affect renal sodium handling and vascular tone, providing a genetic susceptibility profile that complements blood pressure monitoring and lifestyle assessment.
2. How accurate is the test and is it accepted by DHA?
Direct Answer: Our ISO 9001:2015‑accredited NGS platform achieves over 99.9% analytical sensitivity and specificity, fully recognised under DHA/MOHAP molecular diagnostics guidelines. The laboratory is licensed under DHA Facility License 1143 and follows rigorous quality control, including liquid chromatography‑mass spectrometry (LC‑MS/MS) confirmation for positive findings. All reports comply with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 on health ICT use.
3. What preparation is needed before sample collection?
Direct Answer: You must complete a mandatory pre‑genetic counselling session to discuss your family history and sign informed consent before the blood draw. No fasting is required; however, provide a detailed clinical history of any hypertension diagnoses and current medications. Our coordinator will guide you through the consent process and arrange a VIP mobile phlebotomy at your home or workplace between 8 AM and 11 PM. The counselling ensures you understand the implications and complies with PDPL 2021 and Federal Law No. 2 of 2019.
UAE Regulatory & Data Privacy Adherence
Your data is protected. DNA Labs UAE operates under the full legal framework of the United Arab Emirates. All genetic and personal information is processed in accordance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent follow Federal Decree‑Law No. 4 of 2016 on Medical Liability. This test is conducted under DHA Facility License 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | ADD2 Gene Hypertension Genetic Test (NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole blood (peripheral) – VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection |
| Methodology Used | Next‑Generation Sequencing (NGS) with LC‑MS/MS variant confirmation |
| ICD‑10‑CM Code | I10 |
| LOINC Code | 48018-6 |
| DHA Facility License & Address | License 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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