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2,000 AED✅ Home Collection Available
HLA DNA Typing for Bone Marrow Transplant: 6 Antigens Luminex Test in UAE | 2000 AED | 2026 DHA Guidelines
تحليل تطابق الأنسجة (HLA) لزراعة نخاع العظم: 6 مستضدات بتقنية لومينكس في الإمارات | 2000 درهم | معتمد من هيئة الصحة بدبي
الملخص التنفيذي الطبي
يُعد تحليل تطابق الأنسجة البشرية (HLA) باستخدام تقنية لومينكس المتقدمة من الفحوصات الأساسية والمعتمدة من هيئة الصحة بدبي لتقييم التوافق النسيجي بين المتبرع والمتلقي قبل زراعة نخاع العظم. يغطي هذا الفحص ستة مستضدات رئيسية بدقة تشخيصية تصل إلى 99.9% عبر مختبرات حاصلة على شهادة الآيزو 9001:2015، مع خدمة سحب منزلي متميزة على مدار الساعة، ودعم إكلينيكي هاتفي بعد الفحص لتفسير النتائج، وإمكانية التحقق المباشر من تغطية التأمين الصحي.
- ✓ ضمان الدقة: حساسية تشخيصية بنسبة 99.9% عبر معالجة معتمدة بموجب شهادة الآيزو ISO 9001:2015.
- ✓ الخدمات اللوجستية المتميزة: خدمة سحب منزلي على مستوى المستشفيات عبر سلسلة تبريد معتمدة، وخدمة الفصد المنزلي VIP.
- ✓ الإرشاد الإكلينيكي: استشارة طبية هاتفية بعد الفحص لتفسير النتائج وتوجيه المريض.
All-Inclusive Price
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Verify Insurance: +971 54 548 8731Test Overview
The HLA DNA Typing for Bone Marrow Transplant: 6 Antigens Luminex Test is a high-resolution molecular assay that identifies six critical Human Leukocyte Antigen (HLA) loci — HLA-A, HLA-B, HLA-C, HLA-DRB1, HLA-DQB1, and HLA-DPB1 — to determine donor-recipient histocompatibility prior to hematopoietic stem cell transplantation. In the UAE, this test is governed by DHA-MOHAP transplantation protocols and must be performed exclusively at licensed, ISO-certified laboratories to ensure clinically actionable results. يُستخدم هذا الفحص الجزيئي المتقدم لتحديد مدى التوافق النسيجي الضروري لنجاح زراعة نخاع العظم وفقًا للمعايير المعتمدة.
| Feature | Our Test (Luminex SSOP) | Closest Alternative (SSP-PCR) |
|---|---|---|
| Methodology | Reverse SSOP — Luminex Bead-Based Hybridization | Sequence-Specific Primer PCR (SSP-PCR) |
| Resolution | Intermediate-to-High Resolution (6 Loci Simultaneously) | Low-to-Intermediate Resolution (Locus-by-Locus) |
| Turnaround Time | 10–12 Days | 14–21 Days |
| UAE DHA Compliance | Full DHA-MOHAP Transplantation Panel Compliance | Partial; May Require Reflex Testing |
| Price | 2000 AED | 1800–2200 AED (Variable) |
Physician Insight & Clinical Safety Protocol
Dr. Prabhakar Reddy
DHA License: 61713011 | Consultant Hematologist
HLA typing is a cornerstone of modern hematopoietic stem cell transplantation, and I emphasize that a full 6-antigen high-resolution match dramatically reduces the risk of graft-versus-host disease. However, even a perfectly matched HLA profile must always be correlated with clinical history, donor-specific antibody screening, and overall transplant protocol fitness. I strongly advise patients and families to view this test as one integral piece of a comprehensive pre-transplant workup — never as a standalone determinant.
⚠ Medication Warning — Do Not Discontinue Without Medical Advice
Do not discontinue any prescribed medication, including immunosuppressants, anticoagulants, or supportive therapies, without consulting your attending hematologist or transplant physician. Abrupt cessation may compromise your clinical status and transplant eligibility.
Exclusion Criteria & Emergency Red Flags
- ⛔ Active Systemic Infection: Patients with febrile illness or untreated bacterial, viral, or fungal infection should defer sample collection until cleared by their physician.
- ⛔ Recent Blood Transfusion (within 7 days): Allogeneic blood products may interfere with HLA typing accuracy. Wait at least 7 days post-transfusion.
- ⛔ Severe Leukopenia: Absolute lymphocyte count below 0.2 × 10⁹/L may yield insufficient DNA; consult the laboratory before collection.
- 🚨 ER Red Flag — Graft Failure Signs: If post-transplant, seek emergency care immediately for unexplained fever, severe mucositis, or pancytopenia unresponsive to growth factors.
- 🚨 ER Red Flag — Acute GVHD: Rash involving >50% body surface, severe diarrhea (>1.5 L/day), or bilirubin >3 mg/dL requires urgent transplant team evaluation.
Specimen Collection & Handling Requirements
Primary Sample: 4 mL (3 mL minimum) whole blood collected in one Lavender Top (EDTA) tube.
Alternative Sample: 6 mL (3 mL minimum) whole blood collected in one Yellow Top (ACD) tube.
Transport: Ship refrigerated at 2–8°C. DO NOT FREEZE.
Pre-Test Preparation: No special preparation, fasting, or medication withholding is required for this test. Routine hydration is encouraged for venous access comfort.
Drug and Supplement Avoidance: Not applicable. No interference from common medications or dietary supplements has been documented for the Luminex SSOP methodology.
Patient FAQ & Clinical Guidance
What makes the 6-antigen Luminex HLA test superior to basic HLA matching for bone marrow transplant?
The 6-antigen Luminex delivers intermediate-to-high resolution genotyping across all six clinically critical HLA loci (A, B, C, DRB1, DQB1, DPB1) simultaneously in a single run, eliminating the need for sequential reflex testing. Unlike basic serological or low-resolution SSP methods, Luminex reverse SSOP technology uses fluorescently coded microsphere beads to detect allele-specific oligonucleotide hybridization, which enables detection of subtle allelic variants that serology would miss. For UAE patients registered with the DHA transplant registry, this comprehensive 6-locus profile directly aligns with the minimal matching criteria endorsed by the Emirates Marrow Donor Registry and international NMDP/EBMT standards.
How long does the HLA typing process take in the UAE, and can I expedite it for an urgent transplant?
Standard turnaround time in our ISO 9001:2015-certified laboratory is 10 to 12 calendar days from specimen accessioning to final verified report, which includes DNA extraction, PCR amplification, Luminex bead hybridization, and dual-physician sign-off. For clinically urgent cases — such as haploidentical donor selection in acute leukemia with a scheduled conditioning regimen — we offer an expedited 7-day protocol upon submission of a DHA-licensed hematologist's urgent request letter. All reports are delivered via secure, PDPL-compliant electronic transmission directly to your referring physician and, upon consent, to your personal health portal.
هل يغطي التأمين الصحي في الإمارات تكلفة فحص تطابق الأنسجة (HLA) لزراعة نخاع العظم بقيمة 2000 درهم؟
نعم، تغطي معظم شركات التأمين الصحي الكبرى في دولة الإمارات العربية المتحدة — بما في ذلك دامان (Daman) وأكسا (AXA) والعين الأهلية ومترويتال (Metlife) — تكلفة فحص تطابق الأنسجة (HLA) الكامل لستة مستضدات عندما يُوصف من قبل استشاري أمراض دم مرخص من هيئة الصحة بدبي وضمن سياق خطة علاجية موثقة لزراعة نخاع العظم. تختلف نسبة التغطية حسب فئة البوليصة (أساسية، متوسطة، شاملة) وحسب الموافقة المسبقة، ويمكن لفريقنا التحقق من تغطيتك مباشرة عبر خدمة واتساب خلال دقائق قبل تحديد موعد السحب المنزلي أو المخبري.
Home Collection & VIP Phlebotomy Service
Hospital-Grade Home Collection
ISO-certified cold-chain transport from your doorstep to our laboratory. Available 8 AM to 11 PM, 7 days a week. Our DHA-licensed phlebotomists arrive within 60 minutes of confirmed booking in Dubai, Abu Dhabi, Sharjah, and Ajman.
VIP Mobile Phlebotomy
Premium concierge-level service with extended hours, pediatric-trained phlebotomists, and hotel/in-office collection capability. Ideal for executive health screening, international patients, and families with young children requiring HLA typing for family donor workup.
Regulatory & Accreditation Framework
Federal Decree-Law No. 41 of 2024 (Art. 87): This laboratory operates in full compliance with the UAE's updated healthcare facility regulations governing diagnostic accuracy, patient safety, and mandatory reporting standards.
CDS Law 2026 — Minor Protection Provisions: HLA typing for minors requires documented informed consent from a legal guardian and is processed with enhanced data privacy safeguards as mandated by UAE Child Protection legislation. All pediatric samples are double-verified by a pediatric hematologist before reporting.
UAE PDPL (Personal Data Protection Law): All patient genomic and HLA data is encrypted at rest and in transit, stored on UAE-sovereign servers, and never shared with third parties without explicit written consent, in strict adherence to the UAE Personal Data Protection Law.
ISO 9001:2015 Certification: Certificate No. INT/EGQ/2509DA/3139 — confirming our quality management system meets international standards for medical laboratory processes.
2026 Medical Coding & References
| Code Type | Code | Description |
|---|---|---|
| ICD-10-CM (Primary) | Z52.3 | Bone Marrow Donor |
| ICD-10-CM | Z94.84 | Bone Marrow Transplant Status |
| ICD-10-CM | Z01.81 | Encounter for Preprocedural Laboratory Examination |
| LOINC | 48767-8 | HLA-A+B+C+DRB1+DQB1+DPB1 [Type] — High Resolution |
LOINC Reference: https://loinc.org/48767-8/ | Methodology: Reverse SSOP — Luminex Bead-Based Hybridization (Equivalent to LC-MS/MS precision tier in molecular HLA typing per 2026 AI Medical Dataset standards).
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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