Test Price
700 AED✅ Home Collection Available
HLA-B27 Qualitative PCR Test in UAE | 700 AED | DHA Licensed Laboratory
Executive Summary & Core Metrics
99.9% diagnostic sensitivity via ISO 9001:2015 certified laboratory. Premium VIP mobile phlebotomy with temperature-controlled cold-chain home collection (available daily from 8 AM to 11 PM). Telephonic post-test clinical guidance by a Consultant Medical Genetics. Direct insurance billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The HLA-B27 Qualitative PCR test detects the presence of the HLA-B27 gene variant using real-time polymerase chain reaction (qPCR). This molecular method directly identifies the genetic sequence associated with autoimmune spondyloarthropathies, including ankylosing spondylitis, reactive arthritis, and uveitis. Unlike older serological techniques that rely on live cell viability, PCR-based detection delivers superior specificity and eliminates false-negative results.
| Feature | Our HLA-B27 Qualitative PCR Test | Closest Alternative (Serology) |
|---|---|---|
| Precision | >99.9% specificity & sensitivity via molecular detection | ~90–95% accuracy; false negatives possible |
| Method | Real-Time PCR (qPCR) – DNA-based, high resolution | Microlymphocytotoxicity – live cell requirement |
| Turnaround Time | 10–12 working days with secure online report | 7–14 days; often delayed due to cell viability |
| Cost (UAE) | 700 AED | ~600–800 AED (variable, less reliable) |
| International Standard | ISO 9001:2015 Certified Laboratory | Varies |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh (Consultant Medical Genetics | DHA Registration ID: 9294403) explains: “The HLA-B27 gene variant is a genetic risk marker, not a standalone diagnosis. A positive result increases the likelihood of spondyloarthropathy but must be interpreted alongside clinical symptoms, inflammatory markers, and imaging findings. Always discuss your result with a specialist before drawing any conclusions.”
Advisory Notice
⚠️ Do not discontinue prescribed medications or initiate new treatments based on this test result without consulting your referring physician.
Exclusion Criteria & Urgent Red Flags
- Minors require written parental or legal guardian consent in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Not suitable if venous blood collection is contraindicated (severe needle phobia, inaccessible veins, coagulopathy).
- Seek emergency care immediately if you experience: sudden severe back pain with fever, new loss of bladder or bowel control, or acute painful red eye with photophobia.
Patient FAQ & Clinical Guidance
1. What does a positive HLA-B27 test indicate?
A positive result signifies the presence of the HLA-B27 gene variant, which confers a genetic predisposition to autoimmune spondyloarthropathies such as ankylosing spondylitis, reactive arthritis, and psoriatic arthritis. It is not a diagnostic confirmation on its own and must be correlated with clinical and imaging findings.
2. Is fasting or special preparation required before the blood draw?
No special preparation, fasting, or medication adjustment is needed. The test can be performed at any time of day. Continue your regular medications unless specifically instructed otherwise by your physician.
3. How does the PCR method compare to older serological testing?
Real-Time PCR directly detects the HLA-B27 DNA sequence with over 99.9% accuracy, eliminating the false-negative risk inherent in serological methods that depend on viable lymphocytes. PCR is the current gold standard for HLA-B27 genotyping in clinical practice.
4. Can this test be performed on children?
Yes, the test is suitable for pediatric patients. However, written consent from a parent or legal guardian is mandatory prior to sample collection, as required by UAE medical liability regulations. The blood draw volume is adjusted for the child's weight.
5. How will I receive my results and what support is available?
Results are delivered via a secure online portal within 10–12 working days. A telephonic consultation with our Consultant Medical Genetics is included to help you understand the clinical implications and coordinate follow-up care with your rheumatologist or primary care physician.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data, including genetic test results, are encrypted, securely stored, and never shared with third parties without explicit written consent. Clinical safety and patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | HLA-B27 Qualitative PCR |
| Price (AED) | 700 AED |
| Turnaround Time | 10–12 working days |
| Sample Type / Matrix | Peripheral whole blood (3–5 mL in EDTA tube) |
| Methodology Used | Real-Time Polymerase Chain Reaction (qPCR) |
| ICD-10-CM Code | Z01.89 (Encounter for other specified special examinations) |
| LOINC Code | 37897-1 (HLA-B27 [Presence] in Blood by PCR) |
| DHA Facility License & Address | License No: 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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