Test Price
3,500 AED✅ Home Collection Available
HLA Single Antigen Bead Assay for Class I IgG Antibodies (DSA-SAB Class I) in UAE | 3500 AED | DHA Licensed
Executive Summary & Core Metrics
The HLA Single Antigen Bead Assay for Class I IgG antibodies (DSA-SAB Class I) is a high-resolution diagnostic tool for detecting donor-specific antibodies directed against HLA-A, -B, and -C antigens. This assay is essential for immunological risk stratification before kidney transplantation, post-transplant surveillance for antibody-mediated rejection, and guiding tailored immunosuppressive therapy. Processed under ISO-accredited protocols with Luminex xMAP technology, it delivers 99.9% diagnostic sensitivity. For insurance coverage verification, contact WhatsApp: +971545488731.
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM – 11 PM).
Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731
Test Overview & Methodology
The HLA Single Antigen Bead Assay for Class I IgG antibodies (DSA-SAB Class I) detects donor-specific antibodies directed against HLA-A, -B, and -C antigens. It is an indispensable tool in kidney transplantation for pre-transplant immunological risk assessment, post-transplant monitoring of antibody-mediated rejection, and guiding immunosuppressive therapy adjustments.
| Feature | Our Test (DSA-SAB Class I) | Closest Alternative (CDC Crossmatch) |
|---|---|---|
| Methodology | Luminex xMAP® technology (multiplex bead-based) | Complement-dependent cytotoxicity (CDC) |
| Sensitivity | 99.9% (single antigen resolution) | ~70-80% (cell-based, limited resolution) |
| Turnaround Time | 10-12 days | 2-3 hours (but not quantitative) |
| Clinical Value | Pre-transplant risk, post-transplant DSA monitoring, virtual crossmatch | Basic histocompatibility, not donor-specific |
Physician Insight & Safety Protocols
Dr. Ajay Singh (General Practitioner, DHA Registration ID: 36234132) states: "The DSA-SAB Class I assay provides a precise immunological fingerprint essential for evaluating transplant recipients. Positive findings must always be correlated with graft function and biopsy results. A negative result does not eliminate all forms of immune injury. Our clinical team is dedicated to guiding you with evidence-based, compassionate care throughout your transplant journey."
Medication Safety Advisory
Important Clinical Instruction
Never discontinue prescribed immunosuppressive medications without consulting your transplant physician. Abrupt changes may trigger acute rejection and compromise graft survival.
Exclusion Criteria & Emergency Red Flags
- Active systemic infection or acute febrile illness – postpone test until full recovery.
- Recent vaccination (especially live-attenuated vaccines) within 2-4 weeks.
- Severe hemodilution or unlabeled sample – recollection mandatory.
- Emergency symptoms: sudden pain over graft site, fever >38.5°C, anuria, or dyspnea – seek emergency medical care immediately.
Patient FAQ & Clinical Guidance
1. What is the purpose of this test?
Direct Answer: This test detects donor-specific IgG antibodies to assess immunological risk before or after solid organ transplantation. The single antigen bead technology identifies precisely which HLA Class I molecules are targeted, enabling accurate risk stratification and tailored immunosuppression.
2. How is the sample collected?
Direct Answer: A dedicated VIP mobile phlebotomy service collects blood under strict temperature-controlled cold-chain protocols at your home between 8 AM and 11 PM. A certified professional draws 2 mL serum (minimum 1 mL) in a serum separator tube; the specimen is refrigerated during transport to our ISO-accredited laboratory.
3. What do positive results indicate?
Direct Answer: Positive donor-specific antibodies indicate potential risk for antibody-mediated rejection, requiring urgent nephrologist consultation. The report includes mean fluorescence intensity (MFI) values, which must be interpreted in conjunction with clinical status and biopsy findings by your transplant team. Positive results do not automatically mean rejection is occurring but warrant immediate clinical correlation.
4. Are there any preparation requirements?
Direct Answer: No fasting is required. Continue all prescribed medications unless specifically instructed otherwise by your physician. Please provide a brief clinical history including transplant date, current immunosuppression regimen, and prior DSA status when booking the appointment.
UAE Regulatory & Data Privacy Adherence
Legal Compliance Framework
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – all patient data encrypted and processed within DHA-audited secure infrastructure.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – governs electronic health data exchange and telemedicine support.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – establishes patient consent, diagnostic accuracy, and clinical safety standards.
- ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139) – laboratory quality management system.
- DHA standard nomenclature used; all results validated and authorized by a consultant clinical immunologist.
Clinical & Logistical Metadata
| Test Name | HLA Single Antigen Bead Assay for Class I IgG Antibodies (DSA-SAB Class I) |
| Price (AED) | 3,500 AED |
| Turnaround Time | 10-12 business days |
| Sample Type / Matrix | Serum (peripheral blood) – 2 mL in SST, minimum 1 mL. VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM – 11 PM. |
| Methodology Used | Luminex xMAP® – Multiplex Bead-Based Assay with single antigen bead resolution |
| ICD-10-CM Code | Z94.0 (Kidney transplant status), Z76.82 (Awaiting organ transplant status), T86.11 (Kidney transplant rejection) |
| LOINC Code | 77073-3 – HLA class I IgG Ab [Presence] in Serum by Bead-based assay |
| DHA Facility License & Address | DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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