Test Price
2,200 AED✅ Home Collection Available
HLA – Panel Reactive IgG Antibodies (PRA) Class II Quantitative Test in UAE | 2200 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Complimentary Telephonic Post-Test Clinical Correlation with a General Practitioner.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The HLA Panel Reactive IgG Antibodies (PRA) Class II Quantitative Test detects donor-specific antibodies (DSA) against human leukocyte antigens Class II to assess immunological risk before and after organ transplantation. Using multiplex bead-based flow cytometry (Luminex X-Map technology), the assay delivers high-specificity quantification of anti-HLA Class II IgG with single-antigen resolution, reducing false positives and providing precise MFI values for clinical monitoring.
| Feature | Our Test (Luminex X-Map) | Conventional Alternative (ELISA/CDC) |
|---|---|---|
| Precision & Specificity | High specificity – quantifies anti-HLA Class II IgG with single-antigen resolution, reducing false positives. | Lower resolution – may cross-react; cannot distinguish Class I vs Class II IgG, leading to ambiguous results. |
| Methodology | Multiplex bead-based flow cytometry (Luminex X-Map technology), industry gold standard for DSA assessment. | Complement-dependent cytotoxicity (CDC) or solid-phase ELISA; semi‑quantitative, operator‑dependent. |
| Turnaround Time | 10–12 days (rigorous multi‑step validation ensures diagnostic accuracy). | 2–3 days (rapid but lacks granular antibody characterization). |
Physician Insight & Safety Protocols
“As a general practitioner with experience in pre-transplant assessment, I recognise that the HLA PRA Class II IgG assay provides valuable information for evaluating immunological risk. However, laboratory results must always be interpreted in conjunction with full clinical history and current medications. Please do not alter any treatment without consulting your transplant specialist.”
— Dr. Ajay Singh, DHA Registration ID: 36234132
Clinical Safety Advisory
⚠ Important Safety Information
- Medication Warning: Do not discontinue any prescribed immunosuppressive or other medication without consulting your doctor. This test does not replace clinical judgment.
- Interfering Substances: Recent intravenous immunoglobulin (IVIG), plasmapheresis, or rituximab therapy may falsely modulate antibody levels. Inform the laboratory if any of these were administered within the last 30 days.
- Dialysis Timing: Collect sample 48 hours after the last dialysis session to avoid transient protein shifts that can skew results.
- ER Red Flags: If you experience sudden graft site pain, fever, decreased urine output (kidney transplant), yellowing of skin (liver transplant), or acute shortness of breath, seek emergency medical attention immediately. These may indicate acute rejection requiring urgent intervention.
Exclusion Criteria
⚠ Conditions That May Affect Test Validity
- Recent blood transfusion (within 14 days) may cause false positive results.
- Severe haemolysis or lipaemia in the sample may interfere with the assay.
- Pediatric testing: Written informed consent from a legal guardian is mandatory per Federal Decree-Law No. 4 of 2016 on Medical Liability.
ISO 9001:2015 Certified • Facility License: 1143 • Fully compliant with UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
Patient FAQ & Clinical Guidance
1. What is the purpose of the HLA PRA Class II IgG test?
This test quantifies pre‑formed IgG antibodies that target donor Class II HLA molecules, helping transplant teams determine the likelihood of antibody‑mediated rejection and plan desensitization or donor selection accordingly.
2. Why is a 48-hour post-dialysis collection recommended?
Dialysis can transiently alter serum protein composition and clear circulating immune complexes, leading to inaccurate antibody levels. Waiting 48 hours after the session allows equilibration and ensures the result reflects true immunological status.
3. How long does it take to get results, and what does “quantitative” mean?
Turnaround time is 10–12 days because the Luminex assay requires multiple incubation, washing, and analysis steps. “Quantitative” means the report gives the actual amount of antibody (often in MFI or molecules of equivalent soluble fluorochrome), not just “positive/negative,” allowing precise monitoring over time.
4. Can I have the test done at home?
Yes, blood can be collected at your home via our VIP Mobile Phlebotomy service. A certified phlebotomist will visit your residence between 8 AM and 11 PM. The sample is then transported under temperature‑controlled cold chain to our Dubai Healthcare City laboratory.
UAE Regulatory & Data Privacy Adherence
Data Protection & Compliance: DNA Labs UAE operates under DHA Facility License No. 1143. All clinical data are processed in strict adherence to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your personal health information is encrypted, access‑controlled, and never shared without your explicit consent.
Clinical & Logistical Metadata
| Test Name | HLA – Panel Reactive IgG Antibodies (PRA) Class II Quantitative Test |
| Price (AED) | 2,200 AED |
| Turnaround Time | 10–12 business days |
| Sample Type / Matrix | Blood (Serum) |
| Methodology Used | Luminex X-Map bead-based flow cytometry |
| ICD-10-CM Code | Z94.9 |
| LOINC Code | 97262-7 |
| DHA Facility License & Laboratory Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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