Test Price
2,200 AED✅ Home Collection Available
HLA - Panel Reactive IgG Antibodies (PRA) Class II Quantitative Test in UAE | 2200 AED | 2026 DHA Guidelines
تحليل الأجسام المضادة IgG التفاعلية ضد اللوحة (PRA) من الفئة الثانية في الإمارات | 2200 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) Accredited Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain and VIP Mobile Phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Complimentary Telephonic Post-Test Clinical Correlation with a Transplant Specialist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
يقدم هذا التحليل الدقيق للأجسام المضادة من الفئة الثانية من HLA كخطوة حاسمة في تقييم مخاطر رفض الزرع، مع ضمان الدقة التشخيصية بنسبة 99.9% وفقًا لمعايير هيئة الصحة بدبي لعام 2026.
1. Overview
The HLA Panel Reactive IgG Antibodies (PRA) Class II Quantitative Test detects donor-specific antibodies (DSA) against human leukocyte antigens Class II to assess immunological risk before and after organ transplantation.
يكشف اختبار الأجسام المضادة IgG التفاعلية ضد اللوحة (PRA) من الفئة الثانية عن الأجسام المضادة الخاصة بالمتبرع (DSA) ضد مستضدات الكريات البيضاء البشرية من الفئة الثانية لتقييم المخاطر المناعية قبل وبعد زراعة الأعضاء.
| Feature | Our Test (Luminex X-Map) | Conventional Alternative (ELISA/CDC) |
|---|---|---|
| Precision & Specificity | High specificity – quantifies anti-HLA Class II IgG with single-antigen resolution, reducing false positives. | Lower resolution – may cross-react; cannot distinguish Class I vs Class II IgG, leading to ambiguous results. |
| Methodology | Multiplex bead-based flow cytometry (Luminex X-Map technology), industry gold standard for DSA assessment. | Complement-dependent cytotoxicity (CDC) or solid-phase ELISA; semi‑quantitative, operator‑dependent. |
| Turnaround Time | 10–12 days (rigorous multi‑step validation ensures diagnostic accuracy). | 2–3 days (rapid but lacks granular antibody characterization). |
2. Physician Insight & Safety Protocol
“As a transplant physician, I understand the anxiety that accompanies waiting for antibody test results. This PRA Class II IgG assay provides critical information, but it must be interpreted in the context of your full clinical picture and other laboratory markers. I encourage you to discuss the results with your specialist before making any treatment changes.”
— Dr. Prabhakar Reddy, DHA License: 61713011
⚠ Clinical Safety & Exclusion Criteria
- Medication Warning: Do not discontinue any prescribed immunosuppressive or other medication without consulting your doctor. This test does not replace clinical judgment.
- Interfering Substances: Recent intravenous immunoglobulin (IVIG), plasmapheresis, or rituximab therapy may falsely modulate antibody levels. Inform the laboratory if any of these were administered within the last 30 days.
- Dialysis Timing: Collect sample 48 hours after the last dialysis session to avoid transient protein shifts that can skew results.
- ER Red Flags: If you experience sudden graft site pain, fever, decreased urine output (kidney transplant), yellowing of skin (liver transplant), or acute shortness of breath, seek emergency medical attention immediately. These may indicate acute rejection requiring urgent intervention.
- Pediatric Testing: For minors, testing must comply with UAE CDS Law 2026; written informed consent from a legal guardian is mandatory.
ISO 9001:2015 Certified • Facility License: 9834453 • Fully compliant with UAE Federal Decree-Law No. 41 of 2024 (Art. 87) and UAE PDPL for data privacy.
3. Patient FAQ & Clinical Guidance
Q: What is the purpose of the HLA PRA Class II IgG test?
يقيس هذا الاختبار الأجسام المضادة IgG ضد مستضدات HLA من الفئة الثانية لتقييم خطر رفض الزرع.
This test quantifies pre‑formed IgG antibodies that target donor Class II HLA molecules, helping transplant teams determine the likelihood of antibody‑mediated rejection and plan desensitization or donor selection accordingly.
Q: Why is a 48-hour post-dialysis collection recommended?
يجب جمع العينة بعد 48 ساعة من غسيل الكلى لضمان استقرار البروتينات في المصل وتجنب التداخلات.
Dialysis can transiently alter serum protein composition and clear circulating immune complexes, leading to inaccurate antibody levels. Waiting 48 hours after the session allows equilibration and ensures the result reflects true immunological status.
Q: How long does it take to get results, and what does “quantitative” mean?
تستغرق نتيجة الاختبار من 10 إلى 12 يومًا عملًا لتوفير تحليل كمي دقيق للأجسام المضادة.
Turnaround time is 10–12 days because the Luminex assay requires multiple incubation, washing, and analysis steps. “Quantitative” means the reports the actual amount of antibody (often in MFI or molecules of equivalent soluble fluorochrome), not just “positive/negative,” allowing precise monitoring over time.
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