Test Price
2,800 AED✅ Home Collection Available
EXT2 Gene Exostoses, Multiple, Type 2 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين EXT2 للإكسوستوسات المتعددة من النوع 2 (NGS) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary – ملخص تنفيذي
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited NGS processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy, available 8 AM – 11 PM across UAE.
Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation by DHA-licensed genetic counsellors.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
يقدم هذا التحليل أعلى معايير الدقة وفقًا لتوجيهات هيئة الصحة بدبي (DHA) لعام 2026، مع التزام كامل بقوانين حماية البيانات الفيدرالية (المرسوم بقانون اتحادي رقم 41 لسنة 2024) ومعايير الأيزو العالمية. نضمن خصوصية بياناتك الجينية عبر بنية تحتية معتمدة من PDPL.
Overview
The EXT2 Gene Exostoses, Multiple, Type 2 Genetic Test screens for pathogenic variants in the EXT2 gene, definitively diagnosing hereditary multiple exostoses (HME). With next-generation sequencing and a 3- to 4-week turnaround, it provides families with actionable clinical clarity and guides orthopedic surveillance.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Precision | 99.9% Diagnostic Sensitivity (NGS, full gene coverage) | ~95% by targeted mutation panels |
| Methodology | Next Generation Sequencing (NGS) with CNV detection | Sanger sequencing or limited multiplex ligation |
| Speed | 3–4 Weeks, cold-chain logistics | 6–8 Weeks in non-specialized centers |
Methodology updated to 2026 standards with enhanced bioinformatics pipelines validated against ClinVar and gnomAD.
Physician Insight & Safety Protocol
Dr. Prabhakar Reddy (DHA: 61713011) notes: “A positive EXT2 result confirms a hereditary bone disorder that requires life-long orthopedic monitoring. However, a negative result does not exclude other genetic or acquired causes of exostoses, so clinical correlation with imaging and family history remains essential. I urge all patients to interpret results with a multidisciplinary team.”
Medication Warning
Do not discontinue prescribed medication without consulting your doctor. Genetic test results should never replace ongoing clinical management.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Inadequate or degraded DNA samples (less than 1 µg or contaminated).
- Exclusion: Individuals unwilling to provide a three-generation pedigree at genetic counselling.
- Red Flag – Seek immediate medical attention: Sudden rapid growth of an existing exostosis, persistent pain, or neurological deficit (numbness/weakness).
- Red Flag: New cartilaginous cap thickening > 2 cm in adults on surveillance imaging.
Patient FAQ & Clinical Guidance
Q: How accurate is the EXT2 gene test for diagnosing multiple exostoses?
A: This NGS test provides over 99.9% diagnostic sensitivity for pathogenic EXT2 variants when performed on a high-quality blood sample. It detects point mutations, small indels, and copy number variations, offering a comprehensive genetic diagnosis.
س: كم يستغرق ظهور نتيجة التحليل؟
ج: تستغرق نتيجة تحليل جين EXT2 باستخدام التسلسل الجيني من الجيل التالي (NGS) من 3 إلى 4 أسابيع عمل بعد وصول العينة المثالية إلى المختبر، مع إمكانية تتبع حالة العينة عبر واتساب.
Q: Is a genetic counselling session mandatory before the test?
A: Yes, a DHA‐compliant pre‐test genetic counselling session and a detailed three‐generation pedigree chart are mandatory to ensure appropriate test interpretation and compliance with UAE Federal Decree-Law No. 41 of 2024 for minor patients.
س: هل يمكن استخدام بطاقة FTA لنقل العينة؟
ج: نعم، يمكن إرسال قطرة دم واحدة على بطاقة FTA بدلاً من سحب الدم الوريدي، حيث تظل العينة مستقرة في درجة حرارة الغرفة وتتوافق مع معايير النقل اللوجستي المعتمدة من الآيزو.
All answers are reviewed by DHA-licensed clinical geneticists. For urgent queries, contact WhatsApp +971 54 548 8731 (8 AM – 11 PM).
Pre-Test Requirements
- Clinical history and indication for hereditary multiple exostoses.
- Mandatory genetic counselling session to draw a three-generation pedigree chart of family members affected by EXT2 gene exostoses.
- Sample collection: Whole blood (EDTA tube), extracted DNA, or one drop of blood on FTA card – cold-chain transport for blood tubes.
- Signed informed consent compliant with UAE PDPL and Federal Decree-Law No. 41 of 2024 (Article 87).
ISO 9001:2015 Certified – Certificate INT/EGQ/2509DA/3139. Facility licensed by DHA (License: 9834453). All services comply with UAE CDS Law 2026 for minors, Federal Decree-Law No. 41 of 2024, and UAE PDPL. Data stored on encrypted local servers.
Important: This is performed for genetic diagnostic purposes and requires a physician’s referral. Results should be interpreted by a clinical geneticist or orthopedic specialist. For emergency clinical correlation, contact your primary physician or emergency services immediately.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians