Test Price
2,800 AED✅ Home Collection Available
NHS Gene Cataract, X‑linked Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل الجين NHS لإعتام عدسة العين المرتبط بالكروموسوم X بتقنية التسلسل الجيني من الجيل التالي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary – ملخص تنفيذي
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited NGS processing.
Premium Logistics: ISO Certified Cold‑Chain Home Collection by trained phlebotomists, 8 AM – 11 PM UAE‑wide.
Clinical Guidance: Post‑test telephonic genetic counselling session with result interpretation.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
ضمان الدقة: حساسية تشخيصية بنسبة 99.9% عبر معالجة معتمدة وفق معيار ISO 9001:2015. الخدمات اللوجستية: سحب منزلي بسلسلة تبريد معتمدة على مستوى الإمارات. الإرشاد السريري: جلسة استشارة وراثية هاتفية بعد النتيجة. التأمين: تحقق مباشر من الموافقة عبر واتساب.
Comprehensive NGS‑Based NHS Gene Analysis for X‑Linked Cataract
This next‑generation sequencing (NGS) test screens the entire coding region of the NHS gene to confirm or exclude pathogenic variants associated with Nance‑Horan syndrome—an X‑linked disorder characterized by congenital cataract, dental anomalies, and intellectual disability. يقوم هذا الفحص بتسلسل الجين NHS كاملاً لتأكيد أو استبعاد الطفرات المسببة لمتلازمة نانس‑هوران.
| Feature | Our Test (DHA/MOHAP Standard) | Closest Alternative (Sanger / WES) |
|---|---|---|
| Precision | 99.9% sensitivity for single‑nucleotide, indel, copy‑number changes | ~95% sensitivity; may miss deep intronic or mosaic variants |
| Method | Targeted NGS (Illumina® platform) with complete gene coverage | Sanger sequencing (single‑exon) or whole‑exome with gap risk |
| Turnaround | 3–4 weeks from sample receipt | 6–12 weeks (WES); 4–6 weeks (Sanger) |
Physician Insight & Safety Protocol
“As a clinician, I emphasize that a genetic result alone does not define a patient’s future. An NHS variant must be interpreted alongside a full ophthalmic and systemic evaluation. I encourage families to use this test as a compass, not a verdict, and to discuss all findings with their treating ophthalmologist and genetic counsellor.” – Dr. Prabhakar Reddy, DHA Licence No. 61713011.
⚠️ Medication Warning: Do not discontinue any prescribed medication or eye drops without explicit instruction from your consultant. Genetic testing does not replace ongoing clinical care.
Exclusion Criteria & Emergency Red Flags
- Inability to provide a clinical history or three‑generation pedigree chart.
- Severe haemolysis, clotted specimen, or insufficient DNA yield.
- Active anticoagulation above therapeutic range – sample collection deferred.
- Patient unwilling to attend mandatory pre‑test genetic counselling session.
🔴 If you experience sudden vision loss, intense eye pain, flashes of light, or severe headache after sample collection, seek emergency ophthalmologic care immediately.
Patient FAQ & Clinical Guidance
How accurate is the NHS gene test for diagnosing Nance‑Horan syndrome?
Snippet: With 99.9% analytical sensitivity, our NGS test reliably identifies single‑nucleotide variants and copy‑number changes across all coding exons of the NHS gene.
بدقة تصل إلى 99.9%، يحدد الاختبار الطفرات النقطية والتغيرات في عدد النسخ عبر جميع الإكسونات المشفرة لجين NHS.
What sample type is required and how is the home collection performed?
Snippet: We accept whole blood, extracted DNA, or a single drop dried on an FTA card, collected at your home between 8 AM and 11 PM.
يُقبل الدم الكامل أو الحمض النووي المستخلص أو نقطة دم على بطاقة FTA، ويتم السحب المنزلي بين 8 صباحاً و11 مساءً.
How should I interpret my results and what are the next steps?
Snippet: A positive result confirms the X‑linked NHS variant, guiding cascade testing in maternal relatives and early cataract management from infancy.
النتيجة الإيجابية تؤكد الطفرة المرتبطة بالكروموسوم X، مما يستدعي فحص الأقارب من جهة الأم والتدخل المبكر لإعتام عدسة العين.
Pre‑Test Information
A complete clinical history including age at cataract onset, extra‑ocular features, and a three‑generation pedigree must be submitted prior to sample collection. A mandatory pre‑test genetic counselling session will be scheduled to review the’s scope, possible outcomes, and implications for at‑risk family members. Fasting is not required, but patients on anticoagulants must inform the phlebotomist during home collection.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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