Test Price
4,800 AED✅ Home Collection Available
Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel | 4,800 AED | Clinical Genetics Test
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
- Clinical Guidance: Post-Test Telephonic Consultation for Result Interpretation.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This advanced NGS-based gene panel examines nuclear and mitochondrial DNA to identify pathogenic variants associated with Leigh syndrome and mitochondrial encephalopathy. It enables precise diagnosis, carrier screening, and informed clinical decision-making for at-risk families.
| Feature | Our Test (NGS Panel) | Closest Alternative (Whole Exome Sequencing) |
|---|---|---|
| Precision | >99.9% Analytical Sensitivity for targeted genes | ~95% for mitochondrial variants; incidental findings risk |
| Methodology | Targeted NGS with deep exon coverage | Whole Exome Sequencing |
| Turnaround Time | 4–6 weeks | 8–12 weeks |
| Sample Types | Amniotic fluid, CVS, peripheral blood | Blood, tissue (limited prenatal) |
Physician Insight & Safety Protocols
“This gene panel provides precise molecular insights into Leigh syndrome and mitochondrial encephalopathy, yet results must be integrated with clinical history, metabolic workup, and neuroimaging. I strongly advise families to discuss findings with a specialized paediatric neurologist or clinical geneticist. Never adjust or discontinue prescribed therapies based solely on genetic results without direct consultation with your treating physician.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA: 9294403)
Clinical Safety Advisory
Safety Warnings
- Exclusion: Patients with active bleeding disorders or haemodynamic instability must not undergo blood draw without medical supervision.
- Exclusion: Invasive prenatal sampling (amniocentesis/CVS) must be performed by an obstetric specialist within a hospital setting; home collection is strictly unavailable for these procedures.
- ER Red Flags: If the patient experiences acute neurological decline, seizures, respiratory distress, or metabolic crisis, seek emergency care immediately—do not delay for genetic results.
- Genetic test results are not a substitute for urgent clinical evaluation.
Patient Exclusion Criteria
Who Should Not Take This Test
- Patients with an active bleeding disorder or haemodynamic instability unless under direct hospital supervision.
- Prenatal genetic testing without prior genetic counselling and obstetric clearance.
- Individuals with a recent blood transfusion (within 2 weeks) may experience altered results; consult your physician.
Patient FAQ & Clinical Guidance
1. What sample is required for the Leigh Syndrome gene panel?
Summary: Accepted samples include amniotic fluid, chorionic villi (CVS), or peripheral blood, depending on clinical indication and patient age.
All sample collections occur strictly within a hospital setting. For blood draws, a standard venipuncture is performed by trained phlebotomists in DHA‑licensed facilities. Amniocentesis and CVS are conducted by obstetric specialists.
2. How long does it take to get the results?
Summary: Results are typically available within 4 to 6 weeks due to the complexity of NGS and bioinformatic analysis.
Turnaround time depends on sample type and volume; we prioritise quality and accuracy. You will receive an SMS notification when the report is ready, followed by a telephonic consultation if requested.
3. Is a doctor's prescription required for this test?
Summary: A valid doctor’s prescription is mandatory; exceptions apply for pre‑surgical workup, pregnancy management, or travel clearance.
Under UAE regulations, a prescription from a licensed physician (General Practitioner, Paediatrician, Neurologist, or Geneticist) must accompany the request. Exceptions are verified on a case‑by‑case basis.
UAE Regulatory & Data Privacy Adherence
This test complies with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent follow the provisions of Federal Decree‑Law No. 4 of 2016 on Medical Liability. The laboratory operates under DHA/MOHAP standards and is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel |
| Price (AED) | 4,800 |
| Turnaround Time | 4 to 6 weeks |
| Sample Type / Matrix | Amniotic fluid, Chorionic villus sampling (CVS), Peripheral blood – Hospital extraction only |
| Methodology Used | Targeted NGS panel with deep exon coverage including mitochondrial and nuclear genes |
| ICD-10-CM Code | G31.82 (Leigh syndrome), G31.81 (Mitochondrial encephalopathy) |
| LOINC Code | 94050-9 (Mitochondrial DNA full panel) |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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