Test Price
2,800 AED✅ Home Collection Available
SLC27A4 Gene NGS Test for Ichthyosis Prematurity Syndrome (IPS) – 2800 AED – DNA Labs UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation by DHA-licensed specialist.
- Direct Billing Verification: Available via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The SLC27A4 NGS test uses Next-Generation Sequencing to analyze the entire coding region of the SLC27A4 gene, providing a definitive molecular diagnosis for Ichthyosis Prematurity Syndrome (IPS), a rare autosomal recessive disorder characterized by premature birth, thick caseous desquamating skin, and neonatal respiratory distress. Early identification through this test enables targeted dermatological and neonatal management, genetic counselling, and informed family planning.
| Feature | Our ISO-Certified NGS Test | Standard Hospital PCR Panel |
|---|---|---|
| Methodology | Full gene sequencing via NGS (Illumina platform) | Targeted mutation detection (PCR/fragment analysis) |
| Detection Rate | >99.9% of nucleotide variants | ~70–80% (limited to known hotspots) |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Sample Requirement | 2–3 mL whole blood (EDTA) / extracted DNA / FTA card | Whole blood or buccal swab |
| Price in UAE | 2800 AED | 1500–2000 AED |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics specialist, I emphasize that a molecular diagnosis of Ichthyosis Prematurity Syndrome through SLC27A4 sequencing provides the foundation for personalized neonatal care, skin barrier therapy, and family counselling. Results must always be correlated with clinical findings and a detailed pedigree analysis to ensure accurate genetic counseling.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
⚠️ Medication Advisory
Do not discontinue or adjust any prescribed medication without consulting your treating physician. Genetic test results complement, not replace, ongoing clinical management and medication regimens.
⚠️ Exclusion Criteria & Emergency Red Flags
- This test is designed exclusively for germline (constitutional) DNA analysis; it is not valid for somatic mutation profiling or tumor diagnostics.
- Patients who have undergone a bone marrow transplant within the past three months may exhibit mixed chimerism that compromises germline testing accuracy – please inform our phlebotomist prior to collection.
- Seek immediate emergency care if the newborn displays severe blistering, leathery skin, respiratory distress, dehydration, or signs of sepsis. These symptoms may indicate acute complications of Ichthyosis Prematurity Syndrome requiring urgent intervention.
Patient FAQ & Clinical Guidance
1. What is the SLC27A4 genetic test and why is it performed?
This NGS test identifies pathogenic variants in the SLC27A4 gene that cause Ichthyosis Prematurity Syndrome (IPS). It is used to confirm a clinical diagnosis, guide neonatal dermatologic and respiratory management, and provide risk assessment for family planning. The test covers the entire coding region and splice sites for comprehensive mutation detection.
2. How is the sample collected and what is the turnaround time?
A certified phlebotomist will visit your home for a 2–3 mL blood draw (EDTA) between 8 AM and 11 PM, seven days a week. Alternatively, you may submit an FTA card dried blood spot or previously extracted DNA. The sample is transported via temperature-controlled cold chain to our ISO 9001:2015 accredited laboratory. Results are reported within 3 to 4 weeks, accompanied by a telephonic consultation with a DHA-licensed genetics specialist.
3. Can this test be used for carrier screening or prenatal diagnosis?
Yes, the SLC27A4 NGS test is validated for carrier screening in at-risk couples and for prenatal diagnosis using amniocytes or chorionic villi samples. A pre-test genetic counselling session is mandatory to discuss implications, risks, and consent. The test detects heterozygous carrier status in parents and confirms homozygous or compound heterozygous mutations in the fetus, enabling informed reproductive choices.
UAE Regulatory & Data Privacy Adherence
Compliance with UAE Law
This genetic testing service operates in full compliance with the Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data is encrypted and handled with strict confidentiality. Clinical safety and patient consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Our laboratory is DHA-licensed under Facility No. 1143 and is an ISO 9001:2015 certified facility (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | SLC27A4 Gene NGS Test for Ichthyosis Prematurity Syndrome (IPS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole blood (EDTA), extracted DNA, or FTA card |
| Methodology Used | Next-Generation Sequencing (NGS) – Full gene sequencing |
| ICD-10-CM Code | Q80.3 |
| LOINC Code | 90225-7 |
| DHA Facility License & Laboratory Address | DHA Facility License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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