Test Price
2,800 AED✅ Home Collection Available
SLC27A4 Gene Ichthyosis Prematurity Syndrome Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين SLC27A4 لمتلازمة السماك والولادة المبكرة في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary – ملخص تنفيذي
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation by DHA-licensed specialists.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
يُعد هذا الاختبار الجيني المتقدم بتقنية التسلسل من الجيل التالي (NGS) لجين SLC27A4 المعيار الذهبي لتشخيص متلازمة السماك والولادة المبكرة (IPS). نضمن الدقة العالية والالتزام الكامل بقوانين دولة الإمارات العربية المتحدة، بما في ذلك المرسوم بقانون اتحادي رقم 41 لسنة 2024 (المادة 87) وقانون البيانات الشخصية (PDPL). يوفر الاختبار توجيهاً سريرياً بعد الفحص وخدمة سحب منزلي متميزة لضمان تجربة آمنة ومريحة.
Comprehensive Overview
The SLC27A4 NGS test uses Next-Generation Sequencing to analyze the entire coding region of the SLC27A4 gene, providing a definitive molecular diagnosis for Ichthyosis Prematurity Syndrome (IPS), a rare autosomal recessive disorder characterized by premature birth, thick caseous desquamating skin, and neonatal respiratory distress. Early identification through this test enables targeted dermatological and neonatal management, genetic counselling, and informed family planning.
| Feature | Our ISO-Certified NGS Test | Standard Hospital PCR Panel |
|---|---|---|
| Methodology | Full gene sequencing via NGS (Illumina platform) | Targeted mutation detection (PCR/fragment analysis) |
| Detection Rate | >99.9% of nucleotide variants | ~70–80% (limited to known hotspots) |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Sample Requirement | 2–3 mL whole blood (EDTA) / extracted DNA / FTA card | Whole blood or buccal swab |
| Price in UAE | 2800 AED | 1500–2000 AED |
Clinical Expertise & Safety Protocol
“As a clinical geneticist, I remind every family that a genetic diagnosis of Ichthyosis Prematurity Syndrome is not an end but a pathway to proactive care. This test provides the molecular clarity needed to tailor neonatal support, skin barrier therapy, and long-term surveillance; however, results must always be interpreted in the context of a thorough clinical examination and detailed family history.”
— Dr. PRABHAKAR REDDY, DHA License No: 61713011, Consultant Geneticist
⚠️ Medication Warning: Do not discontinue prescribed medication without consulting your doctor. Genetic test results do not replace ongoing clinical management.
⚠️ Exclusion Criteria & Emergency Red Flags
- This test is not suitable for somatic mutation analysis or tumor profiling; it is intended for germline (constitutional) DNA only.
- Patients who have received a bone marrow transplant in the past 3 months may have mixed chimerism that interferes with germline testing – please inform our phlebotomist.
- Seek immediate medical attention (ER) if your newborn exhibits: severe blistering, leathery skin, respiratory distress, dehydration, or signs of sepsis. These could signal acute complications of Ichthyosis Prematurity Syndrome.
Pre‑Test Requirements & Genetic Counselling
A detailed clinical history of the proband is required. A pre‑test genetic counselling session (available via teleconsultation) is mandatory to draw a pedigree chart of family members affected by or carriers of the SLC27A4‑related Ichthyosis Prematurity Syndrome. Any anticoagulant use, recent transfusions, or pregnancy status must be disclosed.
UAE Regulatory Compliance
This service strictly adheres to Federal Decree‑Law No. 41 of 2024 (Art. 87) on medical advertising, the 2026 CDS Law (Minors) requiring guardian consent for genetic testing, and the UAE Personal Data Protection Law (PDPL). Our laboratory holds ISO 9001:2015 Certification (Cert: INT/EGQ/2509DA/3139) and operates under DHA‑licensed facility No. 9834453.
Frequently Asked Questions
What is the SLC27A4 genetic test and why is it used?
The SLC27A4 NGS test diagnoses Ichthyosis Prematurity Syndrome, enabling early intervention and family risk assessment. This comprehensive analysis identifies pathogenic variants in the SLC27A4 gene, which encodes a fatty acid transporter essential for skin barrier and lung surfactant metabolism. Results guide dermatological care, neonatal intensive monitoring, and reproductive planning for couples at risk.
How is the sample collected and when will I receive the report?
A hospital‑grade phlebotomist visits your home for a painless 2‑3 mL blood draw (EDTA) between 8 AM and 11 PM. Alternatively, a dried blood spot on an FTA card or previously extracted DNA can be submitted. After cold‑chain transport to our ISO‑certified lab, the NGS run and expert interpretation are completed within 3 to 4 weeks. You will receive a comprehensive, DHA‑compliant report and a complimentary telephonic clinical guidance session.
Is this test suitable for prenatal diagnosis or carrier screening?
Yes, the SLC27A4 NGS test is validated for both carrier screening of at‑risk couples and prenatal diagnosis via amniocytes or chorionic villi. After a genetic counselling session, the test can detect heterozygous mutations in parents and confirm homozygous or compound heterozygous status in the fetus. Informed consent and pre‑ counselling are mandatory under CDS Law 2026 for minors and prenatal contexts.
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