Test Price
2,800 AED✅ Home Collection Available
SLC10A2 Gene Primary Bile Acid Malabsorption Genetic Test in UAE | 2800 AED | DHA License 1143
Executive Summary & Core Metrics
- 99.9% Diagnostic Sensitivity – ISO 9001:2015 certified facility (Cert: INT/EGQ/2509DA/3139) with Next-Generation Sequencing.
- Premium Logistics – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM – 11 PM).
- Clinical Guidance – Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance – Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
SLC10A2 Genetic Test is a definitive molecular diagnostic that examines the entire coding region of the SLC10A2 gene to identify mutations responsible for primary bile acid malabsorption (PBAM). This test is essential for patients with chronic watery diarrhea, steatorrhea, and a strong family history, guiding precise dietary and pharmacological management.
| Feature | Our Test (DHA-Certified) | Closest Alternative |
|---|---|---|
| Precision / Method | Next-Generation Sequencing (NGS) – full gene coverage | Single‑gene Sanger sequencing (limited exons) or serum 7α‑hydroxy‑4‑cholesten‑3‑one (C4) test |
| Diagnostic Speed | 3‑4 Weeks definitive genotype | Biochemical C4 test: 5‑7 days, but non‑genetic and less specific |
| Sample Type | Blood (EDTA), Extracted DNA, or Dried Blood Spot (FTA Card) – convenient home collection | Serum for C4; invasive colonoscopy for other diagnostics |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh (Consultant Medical Genetics, DHA Registration ID: 9294403) notes: “This genetic analysis is a powerful tool but must be interpreted within the full clinical picture. A negative SLC10A2 result does not rule out other bile acid malabsorption subtypes (e.g., secondary to ileal disease). I strongly urge patients to discuss all findings with a gastroenterologist and never self‑discontinue any prescribed therapy.”
Advisory: Pre-Test Requirements & Medication Warning
- Pre‑test Requirement: A mandatory genetic counseling session to draw a detailed family pedigree and assess inheritance patterns is required before sample collection. Please provide comprehensive clinical history including onset and character of diarrhea, steatorrhea, and previous imaging/endoscopy reports.
- Medication Warning: Do not discontinue prescribed medication (e.g., bile acid sequestrants, anti-diarrheals) without consulting your doctor.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Patients with active gastrointestinal bleeding or hemodynamic instability should delay elective genetic testing until stabilized.
- ER Red Flags: If you experience severe dehydration, rapid weight loss (>5% in one week), or intractable vomiting, seek immediate emergency care rather than waiting for test results.
Patient FAQ & Clinical Guidance
1. What is the SLC10A2 gene primary bile acid malabsorption NGS test?
This advanced genetic analysis detects SLC10A2 gene variants that cause primary bile acid malabsorption with 99.9% diagnostic accuracy. It uses next‑generation sequencing to read all exons of the ASBT gene, providing a definitive molecular diagnosis for this rare metabolic enteropathy.
2. Why is this test recommended?
Clinicians recommend this to confirm a genetic basis for chronic watery diarrhea and steatorrhea unresponsive to dietary changes. It helps distinguish primary bile acid malabsorption from other gastrointestinal disorders, enabling targeted therapy with bile acid sequestrants and improving quality of life.
3. How is the sample collected and what is the turnaround time?
Our certified phlebotomists offer home collection of a small blood sample, with results delivered in 3-4 weeks. We accept whole blood (EDTA), extracted DNA, or a single drop of blood on an FTA card for maximum convenience. All samples are transported in validated cold‑chain conditions.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance
DNA Labs UAE operates under DHA Facility License No. 1143 and adheres to all UAE federal laws governing health data and genetic testing:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring patient data privacy and consent.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – governing the secure handling of electronic health records.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – defining clinical testing safety and patient consent protocols.
Clinical & Logistical Metadata
| Test Name | SLC10A2 Gene Primary Bile Acid Malabsorption Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or Dried Blood Spot (FTA Card) |
| Methodology Used | Next-Generation Sequencing (NGS) – Full Gene Coverage |
| ICD-10-CM Code | K90.4 (Malabsorption due to intolerance, not elsewhere classified) |
| LOINC Code | 92084-0 (SLC10A2 gene full sequencing) |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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