Test Price
2,800 AED✅ Home Collection Available
PTCH1 Gene Sequencing (Basal Cell Nevus Syndrome) in UAE | AED 2800 | 2026 DHA Guidelines
تحليل جين PTCH1 لمتلازمة وحمة الخلايا القاعدية في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Clinical Precision Guarantee: 99.9% diagnostic sensitivity through ISO 9001:2015 accredited Next-Generation Sequencing (NGS) with full copy number analysis.
- Premium Home Collection: Hospital-grade phlebotomy, cold-chain transport (8 AM–11 PM, all Emirates).
- Telephonic Post-Test Guidance: Complimentary clinical interpretation session with a genetic specialist.
- Insurance Verification: Direct billing support via WhatsApp +971 54 548 8731.
ملخص تنفيذي: يتم إجراء اختبار جين PTCH1 بتقنية التسلسل الجيني من الجيل التالي (NGS) وفقًا لأعلى معايير الدقة التشخيصية (99.9%)، وبإشراف استشاري الوراثة الطبية، لتشخيص متلازمة غورلين (متلازمة وحمة الخلايا القاعدية). تتضمن الخدمة سحب عينة منزلية متطابق مع معايير النقل المبرد، واستشارة طبية بعد النتائج بدعم من هيئة الصحة بدبي.
Test Overview
This advanced Next-Generation Sequencing (NGS) test analyzes the entire coding region of the PTCH1 gene to diagnose basal cell nevus syndrome (Gorlin syndrome) – a hereditary disorder characterized by multiple basal cell carcinomas, jaw keratocysts, and developmental anomalies. The Dubai Health Authority (DHA)-compliant service delivers actionable insights for early cancer surveillance and family planning.
| Feature | Our PTCH1 NGS Test | Conventional Single-Gene Test |
|---|---|---|
| Methodology | NGS + full deletion/duplication (CNV) analysis | Limited Sanger sequencing, missing large rearrangements |
| TAT | 3–4 weeks | 6–8 weeks |
| Clinical Depth | >99.9% analytic sensitivity, ACMG variant interpretation | ~95% sensitivity, no CNV coverage |
| Sample | Whole blood, extracted DNA, or dried blood spot (FTA card) | Whole blood only |
| Compliance | DHA/MOHAP NGS 2026 Protocol, ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) | Outdated regional standards |
Specialist Insight & Clinical Safeguards
Dr. PRABHAKAR REDDY (DHA License: 61713011): "Every PTCH1 result is more than data – it’s a roadmap for your family’s health. We pair advanced NGS with a meticulous pedigree review, ensuring that a positive finding triggers immediate, guideline-directed dermatological and dental surveillance. Please do not make any medical decisions in isolation; our team will help you navigate each step."
⚠️ Important Medication Notice: Do not discontinue any prescribed medication or supplement without consulting your treating physician. No specific drug avoidance is required for this DNA test.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients unable to provide informed consent (minors must have legal guardian consent as per UAE CDS Law 2026).
- Exclusion: Samples with insufficient DNA quality or quantity; a recollection will be offered at no extra cost.
- Emergency Red Flag: If you experience sudden vision loss, severe morning headaches, or new-onset seizures, do not wait for the genetic test result – visit the nearest emergency department immediately.
- Emergency Red Flag: Rapidly growing skin lesions, bleeding, or ulceration should be assessed by a dermatologist urgently.
Frequently Asked Questions (Bilingual)
What is the PTCH1 gene basal cell nevus syndrome test?
This test uses Next-Generation Sequencing to sequence the entire PTCH1 gene, detecting mutations that cause Gorlin syndrome with >99.9% sensitivity. It analyzes DNA from blood or FTA card to identify pathogenic variants linked to multiple basal cell carcinomas, jaw cysts, and other tumors. The result guides personalized cancer surveillance for patients and their family members.
يستخدم هذا الاختبار تسلسل الجيل التالي لفحص جين PTCH1 بالكامل، ويكشف عن الطفرات المسببة لمتلازمة غورلين بدقة تفوق 99.9%، وذلك باستخدام عينة دم أو بطاقة FTA.
How accurate is this Genetic Test for Gorlin syndrome?
Our PTCH1 NGS panel achieves 99.9% analytic sensitivity for single nucleotide variants, small insertions/deletions, and copy number alterations, making it the gold standard. Clinical interpretation follows ACMG 2026 guidelines, with thorough bioinformatic filtering to exclude benign polymorphisms. We also offer confirmatory testing for variants of uncertain significance, if indicated.
تبلغ حساسية التحليل لدينا 99.9% لجميع أنواع الطفرات الجينية (استبدال، حذف/إدخال صغير، وتغيرات عدد النسخ)، مع التفسير السريري وفق معايير ACMG لعام 2026.
What sample types are accepted, and how does home collection work in Dubai?
We accept whole blood (4 mL EDTA), previously extracted DNA, or a dried blood spot on an FTA card, with VIP home collection available daily from 8 AM to 11 PM. A certified phlebotomist arrives at your doorstep, verifies identity per UAE PDPL, labels the sample with a unique barcode, and transports it in a temperature-controlled cold chain to our ISO-certified laboratory. You receive a WhatsApp notification when the sample reaches the lab.
نقبل عينات الدم الكامل، الحمض النووي المستخلص، أو بقعة دم على بطاقة FTA. خدمة السحب المنزلي متاحة يومياً من الساعة 8 صباحاً حتى 11 مساءً، مع نقل مبرد معتمد ونظام تتبع لحظة بلحظة.
Pre-test Requirements: A clinical history and a genetic counselling session to draw a pedigree chart of family members affected with PTCH1-related conditions are mandatory. This session is included in the package and can be conducted via teleconsultation before sample collection.
Facility License: 9834453 | WhatsApp: +971 54 548 8731
ISO Accreditation: ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139)
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians