Test Price
2,800 AED✅ Home Collection Available
PRPS1 Gene Phosphoribosylpyrophosphate Synthetase Superactivity Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Trusted Accuracy & Seamless Care
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation by a Consultant Medical Genetics.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
At a Glance
Price: 2,800 AED
Turnaround: 3–4 Weeks
Sample: Whole Blood / Extracted DNA / FTA Card
Method: Next-Generation Sequencing (NGS)
Test Overview & Methodology
The PRPS1 NGS test analyzes the entire coding region of the PRPS1 gene using next-generation sequencing to detect pathogenic variants that cause phosphoribosylpyrophosphate synthetase superactivity, a rare inborn error of purine metabolism. Pathogenic variants are classified according to ACMG guidelines and correlated with biochemical and clinical findings to guide diagnosis, monitoring, and family planning.
| Feature | Our ISO-Certified NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Method | NGS with full gene coverage & advanced bioinformatics | Sanger sequencing of selected exons only |
| Diagnostic Sensitivity | 99.9% | Up to 95% (misses deep intronic/rare variants) |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
| Price (AED) | 2,800 | Often comparable or higher with add‑ons |
| Home Collection | Included (8 AM – 11 PM) | Not standard |
Physician Insight & Safety Protocols
“The PRPS1 NGS test provides critical molecular evidence for phosphoribosylpyrophosphate synthetase superactivity. However, genetic results must be interpreted in conjunction with uric acid levels, enzyme activity assays, and a complete clinical evaluation. A positive result does not automatically dictate therapy; always engage your treating physician for a holistic management plan.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Reg. No. 9294403
Advisory: Pre-Test Requirements & Medication Caution
⚠ Important Safety Notice
Do not discontinue any prescribed medication or alter your treatment plan without first consulting your doctor.
- Pre-Test Requirement: A pre-test genetic counselling session and pedigree chart documentation are mandatory prior to sample collection.
- Sample Types Accepted: Whole Blood, Extracted DNA, or One Drop of Blood on FTA Card; all samples are processed under validated cold‑chain protocols.
- Post-Test Guidance: A telephonic interpretation session with a genetic specialist is included to explain results and next steps.
Exclusion: Emergency Protocols & Contraindications
🚑 Emergency Red Flags
Seek urgent medical care if you experience sudden severe joint pain with swelling (possible acute gouty arthritis), unexplained neurological symptoms (seizures, hypotonia), hearing loss, or signs of metabolic crisis. Call 998 for immediate assistance.
- Exclusion Criteria: This test is not intended for acute emergency diagnosis or for individuals without clinical indication; it is not a substitute for immediate inpatient evaluation.
- Contraindications: Patients with known bleeding disorders or who are unable to provide informed consent should consult their physician before scheduling.
Patient FAQ & Clinical Guidance
1. What does the PRPS1 gene test detect, and what conditions are linked to it?
This NGS test identifies pathogenic variants in the PRPS1 gene causing phosphoribosylpyrophosphate synthetase superactivity, a rare disorder that leads to purine overproduction, hyperuricemia, gout, neurodevelopmental abnormalities, and sensorineural hearing loss. It helps confirm a clinical suspicion and guides long‑term monitoring and family planning. Pathogenic mutations are interpreted according to ACMG guidelines and correlated with biochemical findings.
2. Is a blood sample required, and is home collection truly available across the UAE?
Yes, we accept whole blood, extracted DNA, or a dried blood spot on an FTA card. Home collection is performed by DHA‑licensed mobile phlebotomists daily from 8 AM to 11 PM, covering all Emirates with ISO‑certified cold‑chain transport. The service maintains specimen integrity and eliminates the need to travel to a laboratory.
3. How long until I receive my results, and what does the 2,800 AED price cover?
Results are delivered within 3 to 4 weeks. The comprehensive 2,800 AED fee includes pre‑test genetic counselling, professional sample collection, NGS sequencing, bioinformatics analysis, a detailed clinical report, and a post‑test telephonic interpretation session with a genetic specialist. Direct insurance billing can be verified via WhatsApp at +971 54 548 8731.
4. Will my genetic data be kept private?
Yes. Your genetic information is protected under UAE Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. We store and transmit all data using encrypted, DHA‑compliant systems and never share your results without your explicit consent.
UAE Regulatory & Data Privacy Adherence
Your safety and privacy are governed by the highest UAE standards:
- Data Protection: Compliant with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 concerning the Use of ICT in Health Fields.
- Medical Liability: All clinical procedures adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability, ensuring patient consent and safety.
- Licensing: Operated under DHA Facility License No. 1143. Laboratory certified ISO 9001:2015 (Certificate INT/EGQ/2509DA/3139).
- Corporate Identity: DNA Labs UAE – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | PRPS1 Gene (Phosphoribosylpyrophosphate Synthetase Superactivity) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood, Extracted DNA, or FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) |
| ICD-10-CM Code | E79.8 |
| LOINC Code | 81318-5 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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