Test Price
2,800 AED✅ Home Collection Available
POGZ Gene Sequencing (Mental Retardation, Autosomal Dominant Type 37) Test in UAE | 2,800 AED | 2026 DHA Guidelines
تحليل جين POGZ لتحديد التخلف العقلي الوراثي السائد الجسدي النمط 37 (MRD37) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: Hospital-Grade Home Collection by DHA-Licensed Phlebotomists (8 AM–11 PM) with ISO-Certified Cold-Chain Transport.
Clinical Guidance: Complimentary Post-Test Telephonic Clinical Interpretation by a Senior Genetic Counselor.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731 (within 1 hour).
ملخص تنفيذي: اختبار تسلسل الجين POGZ بتقنية NGS دقيق بنسبة 99.9% وبتكلفة 2800 درهم يشمل استشارة وراثية وسحب منزلي معتمد، مضمون وفقاً لمرسوم القانون الاتحادي رقم 41 لسنة 2024 المادة 87 وقانون حماية البيانات الشخصية في الإمارات.
Clinical Overview & Diagnostic Superiority
The POGZ gene sequencing test detects pathogenic variants causing autosomal dominant mental retardation type 37 (MRD37), a neurodevelopmental disorder marked by intellectual disability, speech delay, and behavioral abnormalities. يستخدم هذا التحليل تقنية التسلسل الجيني من الجيل التالي (NGS) بدقة عالية لتأكيد التشخيص وتوجيه الرعاية الصحية للأطفال والبالغين وفقاً لإرشادات هيئة الصحة بدبي لعام 2026.
| Feature | Our Test (POGZ Gene Sequencing) | Closest Alternative (Whole Exome Trio) |
|---|---|---|
| Methodology | Targeted NGS with 150x mean depth & Sanger confirmation | Whole Exome Sequencing (average 100x), may miss deep intronic regions |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Clinical Scope | Definitive MRD37 diagnosis, parental variant testing | Broad screen, but incidental findings and VUS may delay diagnosis |
| Price | 2,800 AED | 4,500 – 6,000 AED |
| UAE Regulatory Status | DHA/MOHAP Licensed, ISO 9001:2015 | Varies by provider |
Physician Insight & Safety Protocol
Dr. PRABHAKAR REDDY, M.D., DHA License 61713011 — Consultant Neurologist & Clinical Geneticist
“As a clinician, I know that a genetic result alone does not define a child’s future—it must be interpreted alongside developmental milestones, family history, and neurological examination. This test offers families long-awaited answers and unlocks tailored early interventions, but it should never replace compassionate clinical judgement. Please share the report with your treating physician before altering any care plan.”
Medication Warning:
Do not discontinue any prescribed medication, including anticonvulsants, antipsychotics, or stimulants, without consulting your doctor. Genetic testing does not provide immediate therapeutic guidance and must be integrated into your overall care.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Recent blood transfusion (within 4 weeks) may compromise DNA integrity; reschedule accordingly.
- Exclusion: Patients on high‑dose anticoagulants (e.g., warfarin, enoxaparin) require alternative collection (FTA card) to avoid hematoma risk.
- ER Red Flag: If the patient experiences acute suicidal ideation, uncontrolled seizures, or psychotic episodes, proceed immediately to the nearest emergency department—genetic testing does not manage urgent safety concerns.
Patient FAQ & Clinical Guidance
What is the POGZ gene and how does it cause mental retardation?
The POGZ gene encodes a zinc finger protein essential for chromatin remodeling and neuronal development, and pathogenic variants lead to autosomal dominant intellectual disability type 37 (MRD37) characterized by global developmental delay, speech impairment, and distinctive facial features. جين POGZ يشفّر بروتيناً حيوياً لإعادة تشكيل الكروماتين وتطور الخلايا العصبية، وتؤدي طفراته إلى إعاقة ذهنية سائدة جسدية من النمط 37 مع تأخر في النطق وملامح وجهية مميزة.
How is the test performed and what sample is needed?
A certified phlebotomist collects a whole blood sample (or a single drop on an FTA card) during a home visit between 8 AM and 11 PM; DNA is then extracted and sequenced using high‑coverage NGS to detect POGZ mutations with 99.9% sensitivity. يقوم فني معتمد بسحب عينة دم كاملة (أو قطرة واحدة على بطاقة FTA) خلال زيارة منزلية صباحية أو مسائية، ثم يُستخلص الحمض النووي ويُسلسل بتقنية NGS للكشف عن طفرات POGZ بدقة 99.9%.
What do the results mean for my child’s future management?
A definitive genetic diagnosis clarifies prognosis, guides speech/occupational/behavioral therapies, enables informed family planning, and may open access to clinical trials; a board‑certified genetic counselor will explain the implications and next steps in a dedicated post‑test session. يُوضح التشخيص الجيني المؤكد مسار المرض ويُوجه العلاجات التأهيلية والتخطيط الأسري، ويُقدم مستشار وراثي معتمد شرحاً مفصلاً للنتائج والخطوات التالية.
Pre‑ Information & Logistical Note: A genetic counseling session to construct a family pedigree is mandatory. No special dietary restrictions; if on anticoagulants, inform the phlebotomy team to use an FTA card. Sample options: whole blood, extracted DNA, or one drop of blood on an FTA card. Transport is ISO‑certified cold‑chain.
Legal & Regulatory Compliance: This service strictly adheres to Federal Decree‑Law No. 41 of 2024 (Art. 87) on genetic testing consent, the 2026 CDS Law for minors (parental consent required), and the UAE Personal Data Protection Law (PDPL). All data is encrypted and stored in UAE‑sovereign cloud servers.
Facility License: 9834453 | ISO 9001:2015 Certification: INT/EGQ/2509DA/3139 | Support/WhatsApp: +971 54 548 8731.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians