Test Price
2,800 AED✅ Home Collection Available
NLGN3 Gene Autism Susceptibility, X-Linked Type 1 Genetic Test in UAE
Executive Summary & Core Metrics
This NLGN3 next‑generation sequencing test delivers 99.9% diagnostic sensitivity for variants linked to X‑linked autism susceptibility, processed in an ISO 9001:2015 certified facility. Service includes VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM, telephonic post‑test genetic counselling, and direct insurance billing verification via WhatsApp (+971 54 548 8731).
Test Overview & Methodology
The NLGN3 gene test screens for pathogenic variants in the neuroligin 3 gene, implicated in X‑linked autism spectrum disorder. Using targeted next‑generation sequencing (NGS), the complete coding region of the NLGN3 gene is analysed with high analytical precision, providing definitive molecular insight for affected individuals and family planning.
| Parameter | Our NLGN3 NGS Test | Whole Exome Sequencing (Alternative) |
|---|---|---|
| Precision | >99.9% analytical sensitivity for NLGN3 | High, but broader scope; incidental findings possible |
| Method | Targeted NGS (single‑gene focus) | Shotgun NGS across whole exome |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh (Consultant Medical Genetics, DHA Registration ID: 9294403) states: "Targeted sequencing of NLGN3 provides high-resolution detection of variants that confer susceptibility to X-linked autism spectrum disorder. However, a genetic finding must never be interpreted in isolation. Comprehensive developmental, neurological, and behavioural assessments are essential to establish a clinical diagnosis. Pre-test and post-test genetic counselling are strongly recommended for all individuals and families undergoing this evaluation."
Clinical Advisory
Do not discontinue any prescribed medications without consulting your treating physician. No medication adjustments are required before undergoing this genetic test unless explicitly directed by your doctor.
Patient Exclusion Criteria & Safety Precautions
- Exclusion Criteria: Acute febrile illness, recent blood transfusion (within 4 weeks), or known haematological malignancy that may compromise DNA quality.
- Emergency Red Flags: If the patient experiences sudden seizure, loss of consciousness, or rapid behavioural regression, seek immediate emergency care — do not wait for test results.
- Paediatric Consent: Genetic testing of minors requires documented parental or legal guardian consent in compliance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What is the NLGN3 gene test and how is it performed?
The NLGN3 gene test uses advanced next‑generation sequencing to detect mutations associated with X‑linked autism susceptibility. A sample of whole blood, extracted DNA, or a dried blood spot on an FTA card is collected and sent to our accredited laboratory. The complete coding region of the NLGN3 gene is sequenced, and variants are interpreted by clinical molecular geneticists following DHA guidelines.
2. How long does it take to receive results and what does a positive result indicate?
Results are typically available within 3 to 4 weeks from sample receipt at our ISO‑certified laboratory. A positive result indicates the presence of a pathogenic or likely pathogenic variant in NLGN3, which may confirm a genetic predisposition to X‑linked autism spectrum disorder. However, clinical correlation is essential; the test alone does not diagnose autism, and findings should be reviewed with a genetic counsellor and neurologist.
3. Is this test covered by health insurance in the UAE?
Many UAE health insurance plans cover genetic testing when medically necessary and pre‑authorised by a neurologist or clinical geneticist. We offer direct billing verification via WhatsApp (+971 54 548 8731). Our team liaises with insurers to confirm coverage before testing. For self‑pay patients, the price is 2,800 AED, with flexible payment options available.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access‑controlled, and processed exclusively within the UAE jurisdiction. Patient consent is documented prior to testing, and results are shared only with authorised healthcare providers.
Clinical & Logistical Metadata
| Test Name | NLGN3 Gene Autism Susceptibility, X-Linked Type 1 Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood, Extracted DNA, or Dried Blood Spot (FTA Card) — VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM |
| Methodology Used | Targeted Next-Generation Sequencing (NGS) |
| ICD-10-CM Code | Z13.89, F84.0 |
| LOINC Code | 96981-1 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians