Test Price
2,800 AED✅ Home Collection Available
MMP13 Gene Test for Metaphyseal Anadysplasia Type 1 in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 15189 and ISO 9001:2015 accredited next-generation sequencing processing.
- Premium Logistics: VIP Mobile Phlebotomy and temperature-controlled cold-chain home collection, available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic post-test genetic counselling and clinical interpretation by a DHA-licensed Consultant Medical Genetics specialist.
- Insurance: Direct billing verification and pre-approval support via WhatsApp: +971 54 548 8731.
Test Overview & Methodology
This next-generation sequencing (NGS) test screens the entire coding region of MMP13 for pathogenic variants linked to metaphyseal anadysplasia type 1, an autosomal recessive skeletal dysplasia. Ordered by paediatricians, rheumatologists, and clinical geneticists, it delivers a definitive molecular diagnosis to guide clinical management, genetic counselling, and family planning.
| Feature | Our Test (NGS – MMP13 Full-Gene) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Analytical Sensitivity | Greater than 99.9% for single nucleotide variants and small indels | Approximately 99.5%, limited to predefined amplicons |
| Coverage | All exons, splice-site junctions, and deep intronic regions | Selected exons only; may miss deep intronic variants |
| Turnaround Time | 3 to 4 weeks | 4 to 6 weeks |
| Price (AED) | 2800 | 2500 – 3200 (variable) |
| Clinical Report | Pathogenicity classification per ACMG guidelines; includes copy-number analysis | Variant identification only, no structural variant detection |
Physician Insight & Safety Protocols
A positive MMP13 result must be correlated with clinical and radiographic findings to accurately distinguish metaphyseal anadysplasia type 1 from other skeletal dysplasias. Variant interpretation requires comprehensive family history assessment and segregation analysis. I strongly recommend pre-test and post-test genetic counselling for all patients and their families.
— Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403)
Advisory Notice
Medication and Clinical Advisory
Do not discontinue any prescribed medication or supplement without consulting your doctor. This genetic test is not a substitute for ongoing paediatric or rheumatologic care.
Exclusion Criteria and Clinical Red Flags
- Individuals unable to provide a complete clinical history or family pedigree for accurate variant interpretation.
- Testing of minors without appropriate guardian consent as required by UAE Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Seek immediate medical attention if you or your child develop acute bone pain, sudden loss of mobility, or new neurological symptoms — these may signal a complication unrelated to the genetic condition.
- This test must not be used as a standalone diagnostic tool; it requires integration with full clinical and radiological assessment.
Patient FAQ & Clinical Guidance
1. How accurate is the MMP13 NGS test for confirming metaphyseal anadysplasia type 1?
Answer: Our NGS-based MMP13 analysis achieves over 99.9% diagnostic sensitivity for point mutations and small deletions, providing a conclusive molecular diagnosis when clinical suspicion is high. All results are interpreted according to ACMG guidelines and confirmed by a Consultant Medical Genetics specialist.
2. Can I use a home collection service for this test, and how is the sample handled?
Answer: Yes, our ISO-certified VIP mobile phlebotomy team collects a peripheral whole blood or FTA card sample at your home, strictly maintaining temperature-controlled cold-chain integrity from collection to the molecular genetics laboratory. Service is available daily from 8 AM to 11 PM.
3. Will my insurance cover the 2800 AED cost for the MMP13 genetic test?
Answer: Most UAE insurers cover medically necessary genetic testing when pre-authorised. Our team verifies your policy via WhatsApp at +971 54 548 8731 and handles the entire billing process, including direct submission and follow-up.
4. How long does it take to receive results, and what does the report include?
Answer: The turnaround time is 3 to 4 weeks from sample receipt. The clinical report includes full-gene sequencing coverage, variant pathogenicity classification per ACMG guidelines, copy-number analysis, and an interpretive summary for your referring physician.
UAE Regulatory and Data Privacy Adherence
Regulatory Compliance and Data Protection
DNA Labs UAE operates under DHA Facility License Number 1143 and strictly adheres to the following UAE legislative frameworks:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) — ensuring secure collection, processing, and storage of all patient genetic and personal data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields — governing the encrypted transmission and digital handling of health information across all laboratory systems.
Clinical and Logistical Metadata
| Test Name | MMP13 Gene Sequencing for Metaphyseal Anadysplasia Type 1 |
| Price (AED) | 2,800 |
| Turnaround Time | 3 to 4 weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA) or FTA card |
| Methodology Used | Next-Generation Sequencing (NGS) – Full-gene coverage including splice-site junctions |
| ICD-10-CM Code | Q78.5 |
| LOINC Code | 48018-6 |
| DHA Facility License and Laboratory Address | License No. 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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