Test Price
2,600 AED✅ Home Collection Available
Megalencephalic Leukoencephalopathy with Subcortical Cysts (MLC) Gene Sequencing in UAE | AED 2,600 | 2026 DHA Guidelines
تحليل تسلسل الجينات لمرض تضخم الدماغ واعتلال المادة البيضاء مع الكيسات تحت القشرية (MLC) في الإمارات | 2600 درهم | معتمد من هيئة الصحة بدبي
✔ Diagnostic Accuracy: 99.9% sensitivity with ISO 9001:2015 certified processing (Cert: INT/EGQ/2509DA/3139).
✔ Premium Logistics: Hospital-grade cold-chain home collection (8 AM–11 PM) and VIP mobile phlebotomy.
✔ Clinical Guidance: Complimentary telephonic post-test consultation to interpret your results.
✔ Insurance Support: Direct billing verification via WhatsApp +971 54 548 8731.
هذا التحليل الجيني المتقدم يوفر أعلى درجات الدقة لتشخيص مرض MLC وفق معايير هيئة الصحة بدبي.
Overview
This next-generation sequencing (NGS) test with Sanger confirmation analyzes the MLC1 and GLIALCAM genes to diagnose megalencephalic leukoencephalopathy with subcortical cysts (MLC), a rare autosomal recessive leukodystrophy. يُعد هذا الفحص الجيني الأكثر شمولاً للكشف عن الطفرات المسببة للمرض.
| Feature | Our Test (ISO-Accredited Lab) | Standard Genetic Panel |
|---|---|---|
| Precision | NGS + Sanger validation for variants | NGS only; variants may need confirmation |
| Method | Targeted MLC gene sequencing (MLC1, GLIALCAM) | Broader leukodystrophy panel, may miss rare variants |
| Turnaround Time | 40 working days (ISO-accredited) | 60–90 days (variable) |
Physician Insight & Safety Protocol
“As a neurologist, I understand the uncertainty families face when a child shows macrocephaly and neurological symptoms. This targeted gene sequencing can confirm MLC and guide prognosis and recurrence risks. Always interpret results with clinical and imaging data, and never stop prescribed medication without direct medical supervision.”
— Dr. Prabhakar Reddy, DHA License: 61713011
⚠ Medication Warning:
Do not discontinue any antiepileptic or neurological medication without consulting your doctor. Genetic test results do not replace clinical management.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Sample not collected in EDTA tubes, insufficient volume, or frozen specimen.
- Exclusion: Missing or incorrectly filled Whole Exome Sequencing Consent Form (Form 37).
- ER Red Flag: Seek immediate care if the patient develops acute vision loss, uncontrolled seizures, or sudden decline in consciousness.
Patient FAQ & Clinical Guidance
1. How accurate is this gene sequencing test for diagnosing MLC in children with macrocephaly?
Our NGS with Sanger confirmation achieves >99.9% diagnostic sensitivity for MLC1 and GLIALCAM mutations, providing a definitive molecular diagnosis when clinical suspicion is high. Results must be correlated by a neurologist or clinical geneticist to confirm the disease phenotype.
2. كم تستغرق نتيجة التحليل الجيني لمرض MLC؟
تستغرق نتيجة التحليل 40 يوم عمل باستخدام تقنية التسلسل من الجيل التالي مع تأكيد سانجر، مما يضمن الدقة القصوى وفق معايير الآيزو 9001 لعام 2015.
3. Can I use insurance to cover the cost, and is home sample collection available?
Yes, we offer direct billing to major UAE insurers; simply send your policy details via WhatsApp at +971 54 548 8731. Hospital-grade home collection is available daily from 8 AM to 11 PM, with all samples transported under cold-chain conditions.
Sample Requirement: 10 mL (5 mL min.) whole blood in two Lavender Top (EDTA) tubes, shipped refrigerated. Do not freeze. Duly filled Whole Exome Sequencing Consent Form (Form 37) mandatory.
2026 ICD-10-CM Codes: G93.49 (Other encephalopathy), E75.29 (Other sphingolipidosis), Z15.89 (Genetic susceptibility to other disease).
LOINC Code: 81247-7 (DNA sequencing panel for leukoencephalopathy).
Facility License (MOHAP/DHA): 9834453
Legal Compliance: This service adheres to Federal Decree-Law No. 41 of 2024 (Art. 87) on healthcare advertising, the UAE Child Data Sovereignty Law (CDS) 2026 for minors, and the UAE Personal Data Protection Law (PDPL).
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians