Test Price
2,800 AED✅ Home Collection Available
MAN2B1 Gene Alpha-Mannosidosis Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Executive Summary – Core Diagnostic Metrics
- ✓Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited processing (Cert: INT/EGQ/2509DA/3139).
- ⁕Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Daily, 8 AM to 11 PM).
- 🩺Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation with genetic counseling.
- 📄Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The MAN2B1 Gene NGS test identifies pathogenic variants linked to Alpha-Mannosidosis, a rare lysosomal storage disorder. This NGS genetic test offers full-gene coverage with rapid 3–4 week turnaround, ensuring clinical actionability for UAE families. The methodology employs high-depth next-generation sequencing to detect single nucleotide variants, insertions, deletions, and copy number variations across the entire MAN2B1 coding region.
| Feature | Our Test – MAN2B1 NGS | Closest Alternative – Targeted Mutation Panel |
|---|---|---|
| Precision | High-depth NGS, >99.9% sensitivity | Limited to known hotspots |
| Method | NGS (Next Generation Sequencing) | Sanger sequencing / MLPA |
| Speed | 3–4 weeks | 4–6 weeks (fragmented) |
Physician Insight & Safety Protocols
“As a Consultant in Medical Genetics, I emphasize that this test must always be interpreted within the full clinical context, including enzymatic assays and family history. A genetic finding is never a standalone diagnosis, and carrier results require empathetic counseling. Patients should continue all prescribed medical care while awaiting results.” – Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
Critical Advisory
Do not discontinue prescribed medication without consulting your doctor. Genetic test results must always be reviewed by your treating physician. This test is not a substitute for emergency medical care.
Exclusion Criteria & Emergency Red Flags
Exclusion Criteria: This test is not appropriate as a sole diagnostic tool without prior genetic counseling. Patients with acute febrile illness may require rescheduling of sample collection to ensure result accuracy.
🚨 Seek immediate medical attention if you experience: respiratory distress, severe neurological deterioration, loss of consciousness, or signs of metabolic crisis (vomiting, dehydration).
Patient FAQ & Clinical Guidance
1. What is this test used for?
This genetic test detects pathogenic variants in the MAN2B1 gene causing Alpha-Mannosidosis, a rare lysosomal storage disorder. It aids in diagnosis, carrier detection, and reproductive risk assessment by sequencing the entire coding region of the gene to identify variants, deletions, or duplications. Results must be interpreted alongside enzymatic assays and clinical findings by a qualified genetics professional.
2. How is the sample collected, and can it be done at home?
A small peripheral blood sample is collected by a DHA-licensed phlebotomist during a scheduled home visit between 8 AM and 11 PM. The sample is transported via an ISO-certified temperature-controlled cold chain to preserve integrity. This ensures no degradation and reliable results with a 3–4 week turnaround for the genetic analysis.
3. What do the results mean, and who interprets them?
Results report pathogenic, likely pathogenic, or variants of uncertain significance in the MAN2B1 gene. A Consultant Medical Genetics or metabolic specialist interprets the findings in the context of your personal and family medical history. Our post-test telephonic guidance connects you directly with a genetics counselor to discuss implications and next diagnostic steps.
UAE Regulatory & Data Privacy Adherence
Data Protection & Compliance: This diagnostic service complies with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring secure handling of all patient health information.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – governing the safe use of health data and telemedicine.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – overseeing clinical testing safety and informed patient consent.
All genetic data is encrypted, anonymized for analysis, and stored in UAE-based servers under strict access controls. DHA Facility License No. 1143 ensures full regulatory compliance.
Clinical & Logistical Metadata
| Test Name | MAN2B1 Gene Alpha-Mannosidosis Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA tube) or DNA from FTA card |
| Methodology Used | Next Generation Sequencing (NGS) – full-gene coverage |
| ICD-10-CM Code | E77.1 (Defects in glycoprotein degradation) |
| LOINC Code | 51954-0 (MAN2B1 gene mutation analysis in Blood or Tissue by Molecular genetics method) |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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