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Test Price

2,800 AED

✅ Home Collection Available

LPIN2 Gene (Majeed Syndrome) Genetic Test in UAE | 2800 AED

Executive Summary & Core Metrics

Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO‑accredited Next‑Generation Sequencing.

Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).

Clinical Guidance: Complimentary Telephonic Post‑Test Genetic Counselling for result interpretation.

Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

This Next‑Generation Sequencing (NGS) test analyzes the entire LPIN2 gene to identify pathogenic mutations causing Majeed syndrome – a rare autoinflammatory disorder affecting bone (chronic recurrent multifocal osteomyelitis), skin (inflammatory dermatosis), and blood (congenital dyserythropoietic anemia).

Feature Our Test (NGS) Closest Alternative (Single‑Gene Sanger)
Precision Full‑gene coverage, detects SNVs, indels, and CNVs with >99.9% analytical sensitivity Limited to known point mutations; misses large deletions/duplications
Methodology Next‑Generation Sequencing (Illumina platform) with bioinformatic validation Sanger sequencing of individual exons
Turnaround Time 3–4 weeks 4–6 weeks (often with sequential testing)

Physician Insight & Safety Protocols

“This molecular diagnosis provides definitive confirmation of Majeed syndrome; however, interpretation must be integrated with clinical findings, imaging, and laboratory markers. I strongly recommend pre‑ and post‑test genetic counselling to help families understand the autosomal recessive inheritance and reproductive options. Our multidisciplinary team is here to support you at every step.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Advisory & Safety Protocols

⚠ Medication Safety Notice

Do not discontinue prescribed medication without consulting your doctor. Some treatments may affect symptom presentation; always inform your genetic counselor of current medications.

Exclusion Criteria & Red Flags

  • Exclusion Criteria: Insufficient or degraded DNA sample; collection on expired FTA card; active hemolysis interfering with extraction.
  • Exclusion Criteria: Inability to provide informed consent (for minors, legal guardian consent mandatory under UAE Federal Decree-Law No. 4 of 2016 on Medical Liability).
  • Red Flags for Urgent Care: Sudden severe bone pain, high fever (>39°C), pallor with dizziness, or any acute worsening of anemia – seek immediate medical attention.

Patient FAQ & Clinical Guidance

1. What is Majeed syndrome and how does this test help?

Answer: Majeed syndrome is a rare autoinflammatory disorder caused by LPIN2 mutations. This NGS test confirms the genetic diagnosis by sequencing the entire gene, allowing precise identification of pathogenic variants, carrier screening for family members, and informed management planning.

2. What sample types are accepted for this test?

Answer: We accept whole blood (EDTA), extracted DNA, or a single drop of blood on an FTA card. For convenience, our VIP mobile phlebotomy service collects blood at your home under cold‑chain protocols.

3. How long do results take, and what support is provided?

Answer: Turnaround time is 3–4 weeks. You will receive a complimentary telephonic post‑test genetic counselling session to explain the findings, implications for family planning, and potential therapies.

UAE Regulatory & Data Privacy Adherence

This service complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is securely processed and stored in compliance with UAE healthcare data privacy standards. Our laboratory is ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).

Clinical & Logistical Metadata

Test Name LPIN2 Gene (Majeed Syndrome) Sequencing
Price (AED) 2,800
Turnaround Time 3–4 weeks
Sample Type / Matrix Whole blood (EDTA) or extracted DNA
Methodology Used Next-Generation Sequencing (Illumina)
ICD-10-CM Code M86.3
LOINC Code 92708-8
DHA Facility License & Address License #1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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