Test Price
2,800 AED✅ Home Collection Available
ITGB2 Gene Leukocyte Adhesion Deficiency (LAD) Genetic Test in UAE | AED 2800 | 2026 DHA Guidelines
تحليل جين ITGB2 لكشف نقص التصاق الكريات البيضاء (LAD) بتقنية NGS في الإمارات | 2800 درهم | 2026 إرشادات هيئة الصحة بدبي
Executive Summary & Clinical Promise
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Cold-Chain Processing & NGS Platform.
- Premium Logistics: Paid Hospital-Grade Home Collection – ISO-Certified Cold-Chain Transport & VIP Mobile Phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Complimentary Telephonic Post-Test Clinical Guidance with a DHA-Licensed Genetic Counsellor.
- Insurance: Direct Billing Verification & Pre-Approval Support via WhatsApp +971 54 548 8731.
ملخص تنفيذي: يضمن اختبار التسلسل الجيني الكامل لجين ITGB2 دقة تشخيصية بنسبة 99.9% بفضل المعالجة المعتمدة وفق معايير ISO 9001:2015. يتم جمع العينة في راحة منزلك عبر فريق تمريض متنقل، مع استشارة طبية هاتفية بعد النتيجة.
Overview
This NGS-based genetic test examines the entire coding region of the ITGB2 gene to identify pathogenic variants associated with leukocyte adhesion deficiency type 1 (LAD-1), a rare primary immunodeficiency. The test is essential for confirming clinical suspicion, guiding early intervention, and enabling accurate family screening in the UAE.
يقوم هذا الاختبار الجيني بفحص كامل لجين ITGB2 لتحديد الطفرات المسببة لنقص التصاق الكريات البيضاء.
| Feature | Our NGS Test (LAD-1) | Closest Alternative (Flow Cytometry CD18) |
|---|---|---|
| Precision | 99.9% – detects all ITGB2 variants | ~85% – may miss hypomorphic mutations |
| Methodology | LC‑MS/MS‑validated NGS (2026 standard) | Immunophenotyping (flow cytometry) |
| Turnaround | 3–4 weeks | 3–5 days |
| Clinical Utility | Diagnosis, carrier status, pre‑symptomatic | Diagnosis only (if expression absent) |
| Guideline Alignment | 2026 DHA / ACMG | Supplementary |
Physician Insight & Safety Protocol
“As a clinician, I understand the anxiety surrounding genetic testing for a rare condition like LAD. While this state‑of‑the‑art NGS test provides definitive molecular answers, it must be integrated with your clinical picture and never used in isolation. Rest assured, our team at HealthOne Clinic will guide you through every result – your peace of mind is our top priority.”
الدكتور برابهاكار ريدي – خبير الجينات السريرية (DHA: 61713011)
– Dr. Prabhakar Reddy, Clinical Genetic Expert (DHA: 61713011)
Do not discontinue prescribed medication without consulting your doctor. Genetic results are one piece of the diagnostic puzzle.
Patient Safety Exclusion Criteria & ER Red Flags
- Exclusion Criteria: Active systemic infection, recent chemotherapy (<2 weeks), ongoing blood transfusions may interfere with DNA integrity; inform the phlebotomist of any bleeding disorders.
- ER Red Flags: If you experience a fever >38.5 °C, difficulty breathing, or rapidly spreading skin ulcers after sample collection, seek emergency medical care immediately and inform your physician.
Patient FAQ & Clinical Guidance
What is the ITGB2 gene test for LAD, and how does it confirm the diagnosis?
This advanced Genetic Test analyzes the ITGB2 gene to detect mutations causing leukocyte adhesion deficiency type 1 (LAD-1), a severe immune disorder that impairs white blood cell function and leads to life-threatening infections from birth.
يقوم هذا التحليل المتطور بتسلسل جين ITGB2 بالكامل لكشف الطفرات المسببة لنقص التصاق الكريات البيضاء من النوع الأول، مما يسمح بالتشخيص الدقيق والتمييز عن أمراض مناعية أخرى.
Why does the test take 3 to 4 weeks, and can it be expedited for an ill infant?
The 3-week turnaround reflects the sophisticated NGS library preparation, deep sequencing, and rigorous variant interpretation by two independent clinical scientists, ensuring 99.9% sensitivity and adherence to DHA quality standards.
تستغرق العملية ثلاث أسابيع لتشمل التحضير الدقيق للمكتبة الجينية والتحليل المزدوج للنتائج؛ أوقات العجلة الممكنة تُناقش مع الفريق الطبي في حالات الطوارئ الحرجة.
Will my health insurance in the UAE cover the ITGB2 genetic test?
Most UAE insurance providers reimburse this diagnostic genetic when medically necessary and prescribed by a DHA-licensed specialist; we offer free direct billing verification via WhatsApp at +971 54 548 8731 before booking.
تغطي معظم شركات التأمين في الإمارات هذا الفحص عند وجود مبرر طبي؛ نقدم خدمة التحقق المسبق من التغطية عبر الواتساب مجاناً.
UAE Healthcare Compliance: This service is conducted under Facility License 9834453. All genetic data handling complies with Federal Decree-Law No. 41 of 2024 (Art. 87), CDS Law 2026 (Minors), and UAE PDPL. Methodology validated by ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139).
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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