Test Price
2,800 AED✅ Home Collection Available
HESX1 Gene Sequencing for Septo‑Optic Dysplasia – Genetic Test in UAE
Executive Summary & Core Metrics
Executive Summary: Targeted sequencing of the HESX1 gene for definitive diagnosis of septo‑optic dysplasia (SOD) and associated pituitary hormone deficiencies, compliant with DHA regulatory standards and delivered with integrated genetic counselling.
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO‑accredited NGS with orthogonal confirmation.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (daily 8 AM – 11 PM).
- Clinical Guidance: Telephonic pre‑ and post‑test genetic counselling to interpret results and coordinate endocrine / ophthalmologic follow‑up.
- Insurance: Direct billing verification & pre‑approval assistance via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This targeted Next‑Generation Sequencing (NGS) assay analyses the complete coding region and flanking intronic boundaries (±20 bp) of the HESX1 gene. It provides definitive molecular confirmation of septo‑optic dysplasia, enabling precise endocrine management, vision surveillance, and recurrence risk counselling for affected families.
| Test Feature | Our HESX1 NGS Test | Closest Alternative (WES/WGS) |
|---|---|---|
| Methodology | Focused NGS with 100% coverage of HESX1 coding exons ±20 bp flanking introns | Whole‑Exome/Genome Sequencing; may yield incidental findings |
| Turnaround Time | 21–28 working days (3–4 weeks) | 8–12 weeks |
| Clinical Utility | Definitive confirmation of SOD; targeted endocrine & vision management | Broad screening, lower specificity for HESX1 |
Physician Insight & Safety Protocols
“The HESX1 gene test provides a molecular anchor for diagnosing septo‑optic dysplasia, but its full clinical value emerges when integrated with MRI, ophthalmologic assessment, and endocrine profiling. A single genetic result seldom dictates management alone; we interpret it collaboratively with your specialist to ensure a safe, individualised care pathway.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Important: Do not discontinue any prescribed medication, especially corticosteroids or growth hormone, without consulting your attending physician. Abrupt withdrawal may trigger a life‑threatening adrenal crisis. Always consult your specialist before making any changes to your child’s medication regimen.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Acute febrile illness / active infection; inability to provide informed consent (legal guardian must sign); pregnancy is not a contraindication for infant testing.
- ER Red Flags: Sudden vision loss, new‑onset seizures, severe headache, vomiting, lethargy, or signs of adrenal insufficiency (hypotension, shock) – seek emergency care immediately and alert the genetic team.
Patient FAQ & Clinical Guidance
1. What is the HESX1 gene test used for?
The HESX1 gene test diagnoses septo‑optic dysplasia, a rare developmental disorder affecting the brain midline, eyes, and pituitary gland. It confirms the genetic cause, guides hormone replacement therapy, and helps predict recurrence risk in families.
2. How is the sample collected, and is home collection available?
A certified phlebotomist collects a small blood sample at your home, ensuring zero‑contact cold‑chain transport. Extracted DNA from a previous lab can also be used, provided it meets quality criteria. Our VIP mobile service operates daily 8 AM – 11 PM.
3. What is the turnaround time and cost, and does insurance cover it?
Results are reported within 3–4 weeks at a fixed price of 2,800 AED, which includes pre‑test genetic counselling and post‑test interpretation. Many UAE insurers cover the test when a physician cites medical necessity; we verify your policy directly via WhatsApp and assist with prior approval.
UAE Regulatory & Data Privacy Adherence
- Data Protection: All patient genomic and personal data are processed in compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and stored under strict encryption on UAE‑based servers.
- Health Information Governance: Our operations adhere to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, ensuring secure handling of electronic health records.
- Medical Liability & Patient Consent: Informed consent and clinical safety protocols follow Federal Decree‑Law No. 4 of 2016 on Medical Liability.
- Accreditations: ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139); fully DHA‑licensed facility (License No. 1143).
Clinical & Logistical Metadata
| Test Name | HESX1 Gene Sequencing for Septo‑Optic Dysplasia – Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 21–28 working days (3–4 weeks) |
| Sample Type / Matrix | Peripheral venous whole blood |
| Methodology Used | Targeted Next‑Generation Sequencing (NGS) with orthogonal confirmation |
| ICD-10-CM Code | Q04.4 |
| LOINC Code | 81326-7 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians