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Test Price

2,800 AED

✅ Home Collection Available

DUOXA2 Gene Thyroid Dyshormonogenesis Type 5 Genetic Test in UAE | 2800 AED | DHA Licensed

Executive Summary & Core Metrics

Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM, all Emirates).
Clinical Guidance: Complimentary Telephonic Post-Test Clinical Guidance for result interpretation with a senior molecular geneticist.
Insurance & Payment: Direct Billing Verification & Fast Track Approval via WhatsApp +971 54 548 8731.

Test Overview & Methodology

This advanced Genetic Test fully sequences the DUOXA2 gene to identify pathogenic variants responsible for thyroid dyshormonogenesis type 5, a congenital form of hypothyroidism. It delivers a definitive molecular diagnosis, enabling prompt, personalized endocrine management and accurate genetic counselling.

Feature Our Test (DUOXA2 NGS) Closest Alternative (Sanger Sequencing)
Precision 99.9% analytic sensitivity & specificity; full gene coverage including intron-exon boundaries >95% per amplicon; often misses large deletions or deep intronic variants
Method Next Generation Sequencing (NGS) with clinical-grade bioinformatics Capillary electrophoresis-based single‑gene Sanger sequencing
Speed 3 to 4 Weeks 6–8 Weeks (typical gene-by-gene approach)

Physician Insight & Safety Protocols

Lina Osama Zaki Quteineh (DHA Registration ID: 9294403, Consultant Medical Genetics): “I understand the deep concern families feel when awaiting genetic results for a newborn’s thyroid health. This DUOXA2 analysis provides a precise molecular roadmap, but must always be correlated with newborn screening TSH levels, clinical signs, and thyroid ultrasound findings. Maintain all prescribed levothyroxine or other recommended therapies during the testing period.”

Advisory Notice

🚨 Medication Warning

Do not discontinue prescribed thyroid hormone replacement or any other medication without consulting your doctor.

Safety Exclusion & Emergency Red Flags

  • Exclusion Criteria: Inadequate sample volume, gross hemolysis, or improper cold-chain transport; samples not collected following aseptic technique will be rejected.
  • Emergency Red Flags: If the patient (especially an infant) exhibits extreme lethargy, hypothermia, respiratory distress, or feeding intolerance, seek immediate emergency medical attention – do not wait for test results.
  • Pediatric Consent: Testing of minors requires written informed consent from a legal guardian, in full alignment with UAE health regulations including Federal Decree-Law No. 4 of 2016 on Medical Liability.

Patient FAQ & Clinical Guidance

1. What is the DUOXA2 gene test?

This uses Next Generation Sequencing to detect mutations in the DUOXA2 gene that cause thyroid dyshormonogenesis type 5, a treatable form of congenital hypothyroidism.

2. Why would I need this test?

It identifies the genetic cause of congenital hypothyroidism, guiding early treatment and preventing developmental complications. It is often recommended for newborns with abnormal TSH screening or a family history of thyroid dyshormonogenesis.

3. How is the sample collected?

A certified home‑visit phlebotomist collects either a small blood sample in a special tube or a simple finger‑prick drop on an FTA card, maintaining strict cold‑chain from your doorstep to our ISO‑accredited lab.

UAE Regulatory & Data Privacy Adherence

This test is performed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is processed in-country with zero third-party sharing. Clinical safety and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE is DHA-licensed (facility license: 1143) and ISO 9001:2015 certified.

Clinical & Logistical Metadata

Test Name DUOXA2 Gene Thyroid Dyshormonogenesis Type 5 Genetic Test
Price (AED) 2,800 AED
Turnaround Time 3 to 4 Weeks
Sample Type / Matrix Peripheral Blood (Venipuncture or Finger-prick on FTA Card)
Methodology Used Next Generation Sequencing (NGS)
ICD-10-CM Code E03.0 (Congenital hypothyroidism with diffuse goiter)
LOINC Code 90037-0
DHA Facility License & Laboratory Address License: 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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