Test Price
2,800 AED✅ Home Collection Available
CTSD Gene Ceroid Lipofuscinosis Neuronal Type 10 Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM across the UAE.
Clinical Guidance: Telephonic Post-Test Genetic Counselling for result interpretation with a board-certified medical geneticist.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This next‑generation sequencing test analyses the entire coding region of the CTSD gene to detect pathogenic variants causing ceroid lipofuscinosis neuronal type 10 (CLN10), a rare inherited metabolic disorder. It enables accurate diagnosis, carrier screening, and family risk assessment with rapid, ISO‑certified precision.
| Feature | Our Test (NGS – CTSD Full Gene) | Closest Alternative (Single‑Gene Sanger Sequencing) |
|---|---|---|
| Methodology | Next Generation Sequencing (NGS) – comprehensive coverage of coding and splice regions | Sanger sequencing – limited to known mutation hotspots |
| Analytical Sensitivity | 99.9% | ~95% (fragmented regions may be missed) |
| Turnaround Time | 3 – 4 Weeks | 4 – 6 Weeks |
| Price | 2800 AED | Often higher; variable cost structure |
Physician Insight & Safety Protocols
“As a DHA‑licensed Consultant Medical Geneticist, I understand the diagnostic odyssey families face when evaluating neurodegenerative disease in children and adults. This NGS test delivers definitive molecular confirmation of CTSD‑related neuronal ceroid lipofuscinosis type 10. However, results must always be interpreted alongside a comprehensive neurological examination, neuroimaging, and detailed family pedigree. A negative finding does not rule out other NCL subtypes and should prompt consideration of broader genetic testing.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory – Do Not Alter Prescribed Regimens
Never discontinue or adjust prescribed medications without consulting your treating physician. Genetic test results provide diagnostic clarity but are not a substitute for ongoing clinical management. Continue all current therapies, including anti‑seizure and supportive medications, unless explicitly advised otherwise by your neurologist or geneticist.
Exclusion Criteria & Emergency Red Flags
- Patients on anticoagulants may require a specialised blood collection protocol – inform our phlebotomy team at time of booking.
- Testing of asymptomatic minors without written parental consent is prohibited under UAE Federal Law.
- Results must be delivered and discussed by a clinical geneticist or neurologist; self‑interpretation is strongly discouraged and may lead to misinformed decisions.
- Seek emergency medical care immediately if: sudden vision loss, unprovoked seizures, rapid cognitive decline, or loss of previously attained motor skills occur.
Patient FAQ & Clinical Guidance
1. What is the CTSD gene test used for?
This test identifies disease‑causing mutations in the CTSD gene, which are responsible for neuronal ceroid lipofuscinosis type 10 (CLN10), a severe neurodegenerative condition. Next‑generation sequencing examines the entire coding region to detect variants that disrupt the cathepsin D enzyme, essential for lysosomal waste clearance. Neurologists and medical geneticists recommend this test when clinical features such as progressive motor decline, refractory seizures, and early vision loss suggest CLN10 disease.
2. How is the sample collected, and can it be done at home?
Yes, collection can be performed at your residence. A certified phlebotomist will collect one drop of blood on an FTA card, a whole blood sample, or extracted DNA. Our VIP Mobile Phlebotomy service dispatches a DHA‑licensed professional to your home across the UAE between 8 AM and 11 PM daily. The sample is transported in validated temperature‑controlled cold‑chain packaging to our ISO 9001:2015‑accredited laboratory, ensuring chain‑of‑custody integrity and specimen stability throughout transit.
3. What is the accuracy of this test, and when will results be available?
Our ISO‑accredited NGS test delivers 99.9% diagnostic sensitivity with results available within 3 to 4 weeks from sample receipt. Every sequencing run includes internal quality controls and is independently reviewed by two clinical scientists. A detailed molecular report is provided via a secure patient portal, followed by an optional tele‑counselling session with our genetics team to help you and your physician understand the implications for treatment, family planning, and ongoing surveillance.
4. Who should consider this genetic test?
This test is recommended for individuals with clinical symptoms suggestive of neuronal ceroid lipofuscinosis, including unexplained seizures, motor regression, cognitive decline, or vision loss. It is also appropriate for at‑risk family members of a confirmed CLN10 patient, carrier screening for couples with a family history, and prenatal or preimplantation genetic testing after appropriate genetic counselling.
5. Will insurance cover the cost of this test?
Insurance coverage varies by provider and plan. Our team can verify your direct billing eligibility via WhatsApp at +971 54 548 8731. We recommend contacting your insurer in advance to confirm whether genetic testing for neurodegenerative disorders is included in your policy.
UAE Regulatory & Data Privacy Adherence
Data Privacy & Security: All personal health information is processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your genetic data is encrypted, access‑controlled, and never shared with third parties without your explicit written consent.
Patient Safety & Consent: Clinical testing procedures and patient consent protocols adhere strictly to Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring that every sample collection and result disclosure follows the highest standards of medical safety and ethical practice.
Accreditation: ISO 9001:2015 Certified Facility – Cert: INT/EGQ/2509DA/3139. All laboratory processes are audited annually to maintain accreditation.
Clinical & Logistical Metadata
| Test Name | CTSD Gene Sequencing – Ceroid Lipofuscinosis Neuronal Type 10 (CLN10) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 – 4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), FTA Card Dried Blood Spot, or Extracted DNA |
| Methodology Used | Next Generation Sequencing (NGS) – Full Gene Coding Region & Splice Sites |
| ICD-10-CM Code | E75.49 |
| LOINC Code | 93476-7 |
| DHA Facility License & Address | DHA Facility License Number: 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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