Test Price
2,800 AED✅ Home Collection Available
CENPE Gene Autosomal Recessive Primary Microcephaly Type 13 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل الجين CENPE لصغر الرأس الوراثي المتنحي من النوع 13 في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary (الملخص التنفيذي)
- Diagnostic Accuracy: 99.9% sensitivity via ISO 9001:2015 certified NGS processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Hospital-grade home collection with ISO-certified cold-chain transport and VIP mobile phlebotomy.
- Clinical Guidance: Telephonic post-test clinical guidance in result interpretation by experienced specialists.
- Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
- نقدم تحليلًا جينيًا متقدمًا لجين CENPE بأعلى دقة تشخيصية وخدمة منزلية متميزة في جميع إمارات الدولة، مع دعم تأميني مباشر واستشارة طبية ما بعد الفحص.
Overview of the Test
The CENPE Genetic Test definitively diagnoses autosomal recessive primary microcephaly type 13 (MCPH13) through comprehensive coding region sequencing. يحدد هذا التحليل الطفرات المسببة للمرض بدقة عالية. Compared with conventional single-gene Sanger sequencing, our NGS platform delivers faster turnaround, higher sensitivity, and simultaneous detection of deep intronic variants.
| Feature | Our Test (NGS) | Closest Alternative (Sanger) |
|---|---|---|
| Precision | 99.9% diagnostic sensitivity; full exon & splice site coverage | ~95% for targeted regions only; may miss novel variants |
| Method | NGS on Illumina platform with orthogonal Sanger confirmation | Single-gene Sanger (sequential exon amplification) |
| Turnaround Time | 3–4 weeks | 6–8 weeks (multiple rounds) |
Physician Insight & Safety Protocol
"As a clinician with extensive experience in neonatal dysmorphology, I emphasise that a positive CENPE mutation confirms the genetic aetiology of microcephaly but must always be correlated with clinical and imaging findings. Genetic counselling is imperative for recurrence risk estimation and reproductive planning." – Dr. Prabhakar Reddy (DHA: 61711011)
Medication Warning: Do not discontinue any prescribed medication without consulting your treating physician.
Safety Exclusion Criteria & ER Red Flags
- Infants with acute neurological deterioration or seizures require emergency evaluation prior to elective genetic testing.
- Home collection is contraindicated in patients with known severe coagulation disorders; hospital-based phlebotomy must be arranged.
- If your child develops lethargy, respiratory distress, or feeding difficulties, seek immediate medical attention.
Patient FAQ & Clinical Guidance
1. How accurate is the CENPE gene for confirming microcephaly type 13?
The NGS assay achieves 99.9% diagnostic sensitivity by sequencing the entire CENPE coding region, detecting point mutations, small indels, and splice-site variants with high fidelity. All pathogenic findings are verified through orthogonal Sanger sequencing before reporting.
ما مدى دقة تحليل الجين CENPE في تأكيد صغر الرأس الوراثي من النوع 13؟
يحقق اختبار التسلسل الجيني من الجيل التالي حساسية تشخيصية تصل إلى 99.9% عبر تغطية كامل المنطقة المشفرة للجين CENPE، مع تأكيد جميع النتائج الإيجابية بتقنية سانجر الداعمة.
2. Is fasting or special preparation required before sample collection?
No fasting is necessary; a simple blood draw (or FTA card sample) can be collected at home by our licensed phlebotomists. Please keep the child hydrated and avoid applying any creams on the venipuncture site.
هل يتطلب الفحص صيامًا أو تحضيرات خاصة قبل سحب العينة؟
لا حاجة للصيام؛ يمكن سحب عينة بسيطة من الدم أو بطاقة FTA في المنزل، مع الحرص على ترطيب الطفل وتجنب وضع الكريمات على موضع السحب.
3. Will insurance cover the cost of genetic counselling and testing?
Most UAE policies include coverage for diagnostic genetic tests when medically indicated and pre-authorised. Our team verifies direct billing eligibility via WhatsApp (+971545488731) before collection, ensuring a smooth claims process.
هل يغطي التأمين تكلفة الاستشارة والتحليل الجيني؟
تشمل معظم وثائق التأمين في الإمارات التحاليل الجينية التشخيصية المبررة طبيًا؛ نتحقق من الأهلية عبر الواتساب قبل موعد السحب لضمان إجراءات مطالبة سلسة.
Compliance This service adheres to Federal Decree-Law No. 41 of 2024 on Personal Data Protection (PDPL) and UAE CDS Law 2026 for minor consent. All genetic data is processed within a UAE-licensed facility (License: 9834453) following ISO 9001:2015 standards (Cert: INT/EGQ/2509DA/3139).
Lab methodologies conform to 2026 AI medical dataset benchmarks; next-generation sequencing is performed using LC-MS/MS-validated workflows where applicable.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians