Test Price
2,800 AED✅ Home Collection Available
CD96 Gene C Syndrome NGS Test in UAE | AED 2800 | 2026 DHA Guidelines
تحليل الجين CD96 لمتلازمة سي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary & Clinical Promise
يُستخدم تقنية التسلسل الجيني من الجيل التالي (NGS) للكشف عن الطفرات المسببة لمتلازمة "سي" (تثلث الرأس-أوبتز) بدقة تشخيصية تصل إلى 99.9%، مع خدمة السحب المنزلي وفق بروتوكولات النقل المبرد المعتمدة، وإرشاد سريري لاحق يشمل تفسير النتائج.
Comprehensive CD96 Gene Analysis for C Syndrome (Opitz Trigonocephaly)
This test sequences the entire coding region of the CD96 gene using Next‑Generation Sequencing (NGS) to identify pathogenic variants responsible for autosomal dominant C syndrome, a rare dysmorphology condition characterised by trigonocephaly, radial defects, and intellectual disability. Early molecular confirmation empowers paediatric management and genetic counselling.
| Feature | Our CD96 NGS Test (ISO) | Sanger Sequencing Only (Alternative) |
|---|---|---|
| Methodology | Targeted NGS (Illumina) + Sanger confirmation | Single‑gene Sanger sequencing |
| Coverage / Sensitivity | >99.9% for SNVs & indels, 100x depth | ~99% for targeted exons, limited to known regions |
| Turnaround Time | 3–4 weeks from sample receipt | 5–8 weeks typical |
| Bioinformatics | ACMG classification, 2026 variant databases | Manual review only |
| Price | AED 2800 (insurance eligible) | Often higher, limited coverage |
Physician Insight & Safety Protocol
“Dr. Prabhakar Reddy, DHA License 61713011: A positive CD96 variant provides a definitive molecular diagnosis for C syndrome, but it must be correlated with clinical findings such as trigonocephaly and radial ray anomalies. I urge families to review results in conjunction with a paediatric geneticist and a detailed pedigree analysis, as variant interpretation evolves over time.”
🛑 Exclusion Criteria & Emergency Red Flags
- No blood draw if patient has a known severe coagulopathy or active infection at the phlebotomy site.
- For minors (UAE CDS Law 2026), collection requires advance written parental/guardian consent and a paediatric genetic counselling session.
- If the patient exhibits acute respiratory distress, uncontrolled seizures, or severe dehydration on the appointment day, seek emergency care immediately – defer the test until stabilised.
- Our mobile team will not collect if standard cold‑chain conditions cannot be maintained (ambient temperature >35°C outside validated transport containers).
Patient FAQ & Clinical Guidance
1. How accurate is the CD96 NGS test for diagnosing C syndrome?
Our NGS test achieves 99.9% diagnostic sensitivity by sequencing all CD96 coding exons with deep 100x coverage, confirmed by Sanger sequencing for any detected pathogenic variant. The test detects single‑nucleotide variants and small insertions/deletions, but rare deep intronic or large rearrangements may require complementary assays. A negative result reduces the likelihood of C syndrome substantially, though clinical correlation remains essential.
2. كيف يتم جمع عينة فحص الجين CD96؟
نقوم بجمع عينة من الدم الكامل أو بقعة دم مجففة على بطاقة FTA في منزلك عبر فريق تمريض متنقل معتمد، مع نقل مبرد وفق معايير ISO 9001. يُطلب حضور أحد الوالدين لمن هم دون 18 عاماً وتقديم تاريخ سريري موجز وجلسة استشارة وراثية قبل السحب لضمان بناء شجرة العائلة بدقة.
3. Is pre‑test genetic counselling mandatory and how does it work?
UAE Federal Decree‑Law No. 41 of 2024 (Art. 87) and 2026 CDS Law mandate pre‑ counselling, including a three‑generation pedigree chart, to ensure informed consent and privacy protection. A DHA‑certified genetic counsellor will conduct a secure telehealth session, explain autosomal dominant inheritance of C syndrome, and discuss possible implications for the family. This session is included in the AED 2800 package and scheduled before sample collection.
This service complies with UAE Federal Decree‑Law No. 41 of 2024 (Art. 87), CDS Law 2026 (Minors), and UAE PDPL (Data Privacy). Laboratory facility licensed by DHA (License No. 9834453) and certified ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139). All genetic testing requires physician referral and informed consent. Price AED 2800 includes NGS analysis, counselling, and home collection within UAE.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians