Test Price
2,800 AED✅ Home Collection Available
ADK Gene Hypermethioninemia due to Adenosine Kinase Deficiency – Genetic Test in UAE | 2,800 AED | DHA Licensed
Executive Summary & Core Metrics
Executive Summary
- 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited NGS processing at DNA Labs UAE.
- VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Post-Test Clinical Guidance – telephonic interpretation by a DHA-licensed physician.
- Direct Insurance Billing Verification via WhatsApp: +971 54 548 8731.
Test Overview & Methodology
The ADK Gene NGS Test unequivocally identifies pathogenic variants in the adenosine kinase gene, enabling a definitive molecular diagnosis of hypermethioninemia due to adenosine kinase deficiency—a rare inborn error of methionine metabolism.
| Feature | Our Test (NGS) | Closest Alternative (Sanger) |
|---|---|---|
| Precision / Coverage | Full coding region ± splice sites, >99.9% analytical sensitivity | Targeted exon sequencing, ~99% sensitivity for known variants |
| Methodology | Next‑Generation Sequencing (LC‑MS/MS validated library) | Capillary electrophoresis (Sanger) |
| Turnaround Time | 3–4 Weeks (comprehensive bioinformatic analysis) | 6–8 Weeks (sequential exon screening) |
Physician Insight & Safety Protocols
"As a Consultant Medical Genetics specialist, I emphasize that a pathogenic ADK variant confirms the biochemical phenotype, but clinical severity must be correlated with methionine levels and neurological status. This test is a powerful diagnostic tool—not a standalone verdict. My team and I are available to discuss every result within the patient's complete clinical picture."
– Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory Notice – Medication & Dietary Management
Do not discontinue or adjust any prescribed medication, including methionine‑restricted diets or liver‑supportive therapies, without direct consultation with your managing physician.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Active febrile illness, acute hepatitis, or coagulopathy (risk of hematoma).
- Exclusion: Patient unable to provide informed genetic consent (guardian required for minors per Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Red Flag: Sudden confusion, hypotonia, intractable vomiting, or seizures – proceed to ER immediately; do not wait for test results.
- Red Flag: Rapidly progressing hepatic encephalopathy or coagulopathy – urgent metabolic specialist evaluation.
Patient FAQ & Clinical Guidance
1. What does a positive ADK gene test mean for my child's long‑term health?
A positive result identifies a definitive genetic cause of hypermethioninemia, enabling targeted dietary management, methionine monitoring, and neurological surveillance to prevent cognitive decline.
2. How is the sample collected and can it be done at home in Dubai?
A trained phlebotomist performs a quick venipuncture (2–3 mL blood) using our ISO‑certified mobile service, arriving at your doorstep within a 2‑hour window between 8 AM and 11 PM.
3. Is this covered by UAE insurance?
Many UAE insurers cover genetic testing for suspected metabolic disorders when pre‑authorized; send your policy details via WhatsApp to +971 54 548 8731 for instant verification.
UAE Regulatory & Data Privacy Adherence
This genetic test is performed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient genetic data is encrypted, access‑controlled, and processed solely for diagnostic purposes. All clinical procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability to ensure patient safety and informed consent.
Clinical & Logistical Metadata
| Test Name | ADK Gene Hypermethioninemia due to Adenosine Kinase Deficiency – Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood |
| Methodology Used | Next-Generation Sequencing (NGS) |
| ICD-10-CM Code | E72.11 |
| LOINC Code | 81315-5 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians